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ClinicalTrials.gov public records Last synced Oct 10, 2026, 1:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 40 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: 20 ml of ropivacaine 0.5% Clear all
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Efficacy of Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

NCT02712151
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Abdominal Wall Block, Surgical infiltration, Sterile saline, Ropivacaine 0.2%, Ultrasound, Ropivacaine 0.5%
Procedure · Drug · Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
5 Years to 17 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2024 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PENG Block for Arthroscopic Hip Surgery

NCT04508504
View directory record Official record
Conditions
Postoperative Pain, Hip Arthroscopy
Interventions
Preop PENG block, Placebo block, Ropivacaine 0.5% Injectable Solution, Normal Saline
Procedure · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2022 · Synced Oct 10, 2026, 1:01 AM EDT
Recruiting No phase listed Observational

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

NCT04209504
View directory record Official record
Conditions
Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis, Shoulder Disease, Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Repair
Interventions
Ultrasound, Ropivacaine, Bupivacaine, MediPines AGM100 Advanced Respiratory Monitoring System
Diagnostic Test · Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 10, 2026, 1:01 AM EDT
Terminated Not applicable Interventional Results available

Preemptive Femoral & Lateral Femoral Cutaneous Nerve Blocks for THA Acute Pain

NCT01997567
View directory record Official record
Conditions
Internal Derangement of Hip, Acetabular Labrum Tear
Interventions
Ropivacaine, Placebo
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Oak Park, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

Pectoralis Block vs Paravertebral Nerve Blocks for Breast Surgery

NCT04742309
View directory record Official record
Conditions
Breast Surgery
Interventions
Pecs-2 block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Not applicable Interventional

Pain After Laparoscopic Cholecystectomy With Bilateral Tranversus Abdominis Plane (TAP) Block Versus Local Anesthetic Infiltration

NCT01204892
View directory record Official record
Conditions
Postoperative Pain
Interventions
TAP Block, Local infiltration
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 12, 2012 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery

NCT03860974
View directory record Official record
Conditions
Breast Surgery
Interventions
Serratus Plane block (single injection), Paravertebral block (single injection)
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 10, 2026, 1:01 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Effectiveness of Perineural Clonidine as an Adjuvant With Ropivacaine for Popliteal Nerve Block in Patients Undergoing Foot and Ankle Surgery

NCT01986751
View directory record Official record
Conditions
Pain
Interventions
Clonidine, ropivacaine
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 4, 2016 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Femoral Nerve Block Versus Adductor Canal Nerve Block for Peri-Operative Analgesia Following Anterior Cruciate Ligament (ACL) Reconstruction: Evaluation of Post-operative Pain and Strength

NCT03033589
View directory record Official record
Conditions
Pain
Interventions
Marcaine 0.25 % Injectable Solution
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
16 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 10, 2026, 1:01 AM EDT
Withdrawn Not applicable Interventional

Pain Relief Study of Ultrasound Guided Transverse Abdominis Plane(TAP)Block

NCT01217580
View directory record Official record
Conditions
Cesarean Section
Interventions
0.5% ropivacaine, 0.9% sodium chloride
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Regional TAP Block for Bariatric Patients

NCT04051684
View directory record Official record
Conditions
Bariatric Surgery, Transverse Abdominal Plane Regional Blocks
Interventions
Transverse abdominal plane block, Ropivacaine
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Post-Operative Quality of Life Evaluation for Different Anesthesia Techniques for Arthroscopic Shoulder Surgery

NCT01355757
View directory record Official record
Conditions
Rotator Cuff Injury
Interventions
Baxter INFUSOR System, Single Injection of Local Anesthetic
Device · Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2014 · Synced Oct 10, 2026, 1:01 AM EDT
Withdrawn Phase 4 Interventional

Volume vs Concentration: Quadratus Lumborum Blocks With High Volume/Low Concentration or Low Volume/ High Concentration in Nephrectomies

NCT04077398
View directory record Official record
Conditions
Analgesia, Postoperative Pain, Block
Interventions
Ropivacaine 0.5% Injectable Solution
Drug
Lead sponsor
Bruce Ben-David
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 2 Interventional

Stellate Ganglion Block to Augment Trauma-focused Therapy Among Veterans With PTSD

NCT05107752
View directory record Official record
Conditions
PTSD, Trauma and Stressor Related Disorders, Trauma, Psychological, Post Traumatic Stress Disorder
Interventions
Cognitive Processing Therapy (CPT), Stellate Ganglion Block
Behavioral · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 10, 2026, 1:01 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Addition of Clonidine to Ropivacaine in Adductor Canal Block

NCT03057015
View directory record Official record
Conditions
Postoperative Pain
Interventions
Clonidine, Placebo, Ropivacaine, Dexamethasone, Epinephrine
Drug
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

Lumbar Plexus vs Quadratus Lumborum Block in Post-operative Pain Following Total Hip Replacement

NCT03801265
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
Lumbar plexus block, Quadratus lumborum type 3 block, Ropivacaine injection
Procedure · Drug
Lead sponsor
Sharad Khetarpal
Other
Eligibility
18 Years to 90 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2021 · Synced Oct 10, 2026, 1:01 AM EDT
Terminated Not applicable Interventional Results available

Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain

NCT00720330
View directory record Official record
Conditions
Pain, Nausea
Interventions
ropivacaine, Lidocaine/Ketamine, placebo
Drug · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Mayfield Heights, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Oct 10, 2026, 1:01 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Dose Escalation of Dexamethasone to Increase Duration of Transversus Abdominal Plane Block Following Cesarean Section

NCT03098420
View directory record Official record
Conditions
Post Surgical Pain
Interventions
2mg Dexamethasone, 4mg Dexamethasone, Ropivacaine (TAP blocks), Morphine, Bupivacaine Hydrochloride, Normal saline 1ml, Normal saline 0.5ml
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2021 · Synced Oct 10, 2026, 1:01 AM EDT
Completed Phase 4 Interventional Results available

Anterior Cruciate Ligament Pain Study

NCT02604550
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Ropivacaine 0.5%, Percocet 7.5/325, Naprosyn 500 mg
Drug
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Oct 10, 2026, 1:01 AM EDT
Withdrawn Phase 4 Interventional

Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty

NCT02603900
View directory record Official record
Conditions
Acute Pain, Regional Anesthesia Morbidity
Interventions
ropivacaine, bupivacaine, Sham Adductor Canal Catheter, Adductor Canal Catheter
Drug · Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
40 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 10, 2026, 1:01 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Regional Anesthesia Block in Fibula Free Flap Reconstruction

NCT03906838
View directory record Official record
Conditions
Anesthesia, Local, Surgery, Opioid Use, Pain, Postoperative, Head and Neck Neoplasms
Interventions
Ropivacaine injection
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 10, 2026, 1:01 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Ultrasound (US) Guided Supraclavicular Block

NCT00923494
View directory record Official record
Conditions
Analgesia, Pain
Interventions
20 ml of ropivacaine 0.5%, 30 ml of ropivacaine 0.5%, 40 ml of ropivacaine 0.5%
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 64 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2017 · Synced Oct 10, 2026, 1:01 AM EDT
Recruiting Phase 4 Interventional

Comparison of Cryoablation of Pericapsular Nerve Group (PENG) to Fascia Iliaca Catheter in Patients With a Hip Fracture

NCT06278987
View directory record Official record
Conditions
Hip Fractures
Interventions
PENG block and cryoablation, fascia iliaca compartment block
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 10, 2026, 1:01 AM EDT
Terminated Phase 4 Interventional Results available

Continuous Erector Spinae Plane Blocks for Rib Fractures

NCT04558281
View directory record Official record
Conditions
Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
Interventions
Active ropivacaine 0.3% erector spinae plane perineural administration, Placebo erector spinae plane perineural administration
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Oct 10, 2026, 1:01 AM EDT