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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: 25-OH Vitamin D3 Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

To Study the Nutri-Genomic Response of Vit-D Supplementation in African-Americans

NCT02802449
View directory record Official record
Conditions
Hypovitaminosis D
Interventions
25 Hydroxy- Vitamin D3 [25 (OH) D3], Placebo
Drug
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 70 Years
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D and Muscle Metabolic Function

NCT02221596
View directory record Official record
Conditions
Healthy
Interventions
vitamin D, aerobic training
Dietary Supplement · Other
Lead sponsor
David Travis Thomas
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional

Acute Effect of Systemic Stress on Measured Blood Concentrations of 25 (OH) Vitamin D

NCT02460211
View directory record Official record
Conditions
Cardiovascular Disease, Vitamin D Deficiency
Interventions
Vitamin D3, Placebo
Dietary Supplement
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Sep 27, 2026, 9:45 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Variability of 25-hydroxyvitamin D Response From Crystalline 25-hydroxyvitamin D3

NCT01633658
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
cholecalciferol, 25(OH)D
Dietary Supplement
Lead sponsor
Creighton University
Other
Eligibility
20 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 28, 2013 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Clearance of 25-hydroxyvitamin D in Cystic Fibrosis

NCT03104855
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
d6-25-hydroxyvitamin D3
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Single Wintertime Dose of Vitamin D3 to Prevent Winter Decline in Vitamin D Status in Healthy Adults

NCT01924910
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
250,000 IU cholecalciferol as single, oral dose, Placebo
Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional

A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation

NCT05016310
View directory record Official record
Conditions
Breast, Breast Cancer, Osteoporosis
Interventions
High Dose Vitamin D, Standard of Care Vitamin D
Dietary Supplement
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects

NCT00742235
View directory record Official record
Conditions
Healthy Subjects, Vitamin D Deficiency
Interventions
ergocalciferol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Sep 27, 2026, 9:45 PM EDT
Not listed Phase 2 Interventional

Cholesterol and Antioxidant Treatment in Patients With Smith-Lemli-Opitz Syndrome (SLOS)

NCT01773278
View directory record Official record
Conditions
Smith-Lemli-Opitz Syndrome, Cone-Rod Dystrophy, Hearing Loss
Interventions
Antioxidants, Cholesterol
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Up to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

25-Hydroxyvitamin D Pharmacokinetic Study

NCT03401541
View directory record Official record
Conditions
Vitamin D Deficiency, Fat Malabsorption
Interventions
Calcifediol, Calciferol
Drug
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Sep 27, 2026, 9:45 PM EDT
Terminated Early Phase 1 Interventional

Effects of Vitamin D on Renin Expression in Hypertensive Patients

NCT00585442
View directory record Official record
Conditions
Hypertension, Vitamin D Deficiency
Interventions
calcitriol, Placebo
Drug
Lead sponsor
University of Utah
Other
Eligibility
55 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 2 Interventional

A Phase 2 Study of an Oral Vitamin D Compound (DP001) in Secondary Hyperparathyroidism in Patients on Hemodialysis

NCT01922843
View directory record Official record
Conditions
Hyperparathyroidism, Secondary, Kidney Failure, Chronic
Interventions
DP001 softgel capsules, Placebo
Drug
Lead sponsor
Deltanoid Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
14
States / cities
Phoenix, Arizona • Tucson, Arizona • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Sep 27, 2026, 9:45 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

ALPCO 25(OH) Vitamin D CLIA Kit - Fresh Versus Frozen Serum and Plasma Stability Study

NCT07565064
View directory record Official record
Conditions
Vitamin D Deficiency, Vitamin D Insufficiency, Healthy Volunteers
Interventions
ALPCO 25(OH) Vitamin D CLIA Kit
Device
Lead sponsor
American Laboratory Products Company
Industry
Eligibility
22 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Salem, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D Supplementation in Warfighters

NCT02954549
View directory record Official record
Conditions
Vitamin D Deficiency Disease
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation

NCT04556136
View directory record Official record
Conditions
Hypovitaminosis D
Interventions
Standing Phototherapy Kiosk, D3 Oral supplement
Device · Dietary Supplement
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years to 69 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Vitamin D Levels Following Topical Application of Vitamin D Ointment

NCT02676674
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Dose 1, Dose 2
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 2 Interventional Results available

Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)

NCT02186015
View directory record Official record
Conditions
Adult Women, Metastatic Breast Cancer, Estrogen Receptor Positive
Interventions
Cholecalciferol
Drug
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated May 13, 2021 · Synced Sep 27, 2026, 9:45 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers

Vitamin D Status, Disease Specific and Quality of Life Outcomes in Patients With Cutaneous Lupus

NCT01498406
View directory record Official record
Conditions
Cutaneous Lupus Erythematosus
Interventions
vitamin D
Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2013 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial to Assess Response to Oral Vitamin D3 Supplementation in Obese Individuals

NCT00960037
View directory record Official record
Conditions
Obesity
Interventions
Oral vitamin D3, Placebo equivalent
Dietary Supplement
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2012 · Synced Sep 27, 2026, 9:45 PM EDT
Completed No phase listed Observational

Vitamin D3 Supplementation in Pediatric IBD: Weely vs Daily Dosing Regimens

NCT02256605
View directory record Official record
Conditions
Inflammatory Bowel Disease (IBD)
Interventions
Vitamin D-3
Dietary Supplement
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
5 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile

NCT01688102
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Oral Vitamin D3, Ultraviolet Light
Dietary Supplement · Radiation
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 70 Years
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D Absorbance Study - Clinical Trial of the Absorbance of Nano Liquid D3

NCT04885803
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Softgel Vitamin D3, Nano Liquid Vitamin D3, 25(OH)D Blood Serum Test, Placebo Control
Dietary Supplement · Diagnostic Test · Other
Lead sponsor
Inspired Life Medical, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Le Sueur, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 23, 2021 · Synced Sep 27, 2026, 9:45 PM EDT
Not listed Not applicable Interventional

Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications

NCT04229368
View directory record Official record
Conditions
Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 27, 2026, 9:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

UVB Light and Sunscreen

NCT00818467
View directory record Official record
Conditions
Vitamin D Status
Interventions
Tanning spray, UVB
Other
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 50 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Nov 30, 2009 · Synced Sep 27, 2026, 9:45 PM EDT