- Conditions
- Hypertension
- Interventions
- Eplerenone 100 mg daily, Chlorthalidone 25 mg daily, Potassium Placebo, Potassium Chloride
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
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Showing 1–7
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- Conditions
- Heart Failure
- Interventions
- Finerenone (BAY94-8862), Placebo, Inspra (eplerenone)
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,066 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 10
- States / cities
- Birmingham, Alabama • La Jolla, California • Los Angeles, California + 6 more
- Conditions
- Myocardial Remodeling
- Interventions
- Eplerenone, Lactose Tablet
- Drug
- Lead sponsor
- Creighton University
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Central Serous Chorioretinopathy
- Interventions
- 25mg Eplerenone, Placebo
- Drug
- Lead sponsor
- Wills Eye
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 10
- States / cities
- Cherry Hill, New Jersey • Marlton, New Jersey • Mays Landing, New Jersey + 7 more
- Conditions
- Duchenne Muscular Dystrophy
- Interventions
- eplerenone, placebo
- Drug
- Lead sponsor
- Subha Raman
- Other
- Eligibility
- 7 Years and older · Male only
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Cincinnati, Ohio • Columbus, Ohio
- Conditions
- Diastolic Heart Failure
- Interventions
- Eplerenone
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2007
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Metabolic Syndrome, Hypertension, Overweight and Obesity
- Interventions
- Eplerenone, Chlorthalidone with potassium chloride
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2025
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts