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ClinicalTrials.gov public records Last synced Oct 15, 2026, 4:42 PM EDT

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Showing 49–72 of 114 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: 2mA transcranial direct current stimulation Clear all
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study

NCT02512393
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 15, 2026, 4:42 PM EDT
Not listed Not applicable Interventional

Timing of Transcranial Direct Current Stimulation (tDCS) Combined With Speech and Language Therapy (SLT)

NCT03773406
View directory record Official record
Conditions
Aphasia
Interventions
Offline tDCS-before therapy, Sham tDCS, Offline tDCS-after therapy, Online tDCS
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Oct 15, 2026, 4:42 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) and Visual Illusion on Chronic Pain Due to Spinal Cord Injury

NCT01404065
View directory record Official record
Conditions
Chronic Pain, Spinal Cord Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

A Telerehabilitation Program for SCI

NCT04977037
View directory record Official record
Conditions
Incomplete Spinal Cord Injury
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2025 · Synced Oct 15, 2026, 4:42 PM EDT
Withdrawn Not applicable Interventional

Modulating Context Generalization Through Transcranial Direct Current Stimulation

NCT03374605
View directory record Official record
Conditions
Anxiety and Fear
Interventions
active tDCS, sham tDCS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

NCT01539109
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Rehabilitation, Noninvasive brain stimulation: tDCS, Sham tDCS: placebo noninvasive brain stimulation
Behavioral · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Recruiting Not applicable Interventional

Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

NCT07151677
View directory record Official record
Conditions
Aphasia Following Cerebral Infarction, Stroke Ischemic, Fatigue Symptom
Interventions
tDCS (active), Attention-focused sentence comprehension treatment, Sentence comprehension treatment, tDCS (sham)
Device · Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Ann Arbor, Michigan • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 15, 2026, 4:42 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Brain-stimulation on Metamemory Monitoring and Control

NCT03693729
View directory record Official record
Conditions
Healthy
Interventions
HD-tDCS
Device
Lead sponsor
Brooklyn College of the City University of New York
Other
Eligibility
18 Years to 35 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02330315
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Terminated Phase 1Phase 2 Interventional

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety
Interventions
transcranial direct current stimulation using a Soterix mini-CT device
Device
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 28 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2021 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

NCT05521074
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Effects of Transcranial Direct Current Stimulation (tDCS) and Transcranial Ultrasound on Osteoarthritis Pain of the Knee

NCT01404052
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

Maximizing the Impact of Neuroplasticity Using Transcranial Electrical Stimulation Study 2

NCT03896438
View directory record Official record
Conditions
Transcranial Direct Current Stimulation, Schizophrenia, Schizoaffective Disorder
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

Pilot Study of Transcranial Stimulation (tDCS)to Relieve Neuropathic Pain in Cancer Patients

NCT01948050
View directory record Official record
Conditions
Pain
Interventions
non-invasive transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Beth Israel Medical Center
Other
Eligibility
21 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, USA, New York
Source: ClinicalTrials.gov public record
Updated Jul 14, 2014 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

HDtDCS in Logopenic Variant PPA: Effects on Language and Neural Mechanisms

NCT03805659
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
HD-tDCS, Sham
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
45 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Results available

Transcranial Current Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia

NCT01963676
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Auditory Hallucinations
Interventions
tDCS, Sham stimulation
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced Oct 15, 2026, 4:42 PM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Phase 2 Interventional Results available

Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

NCT03826030
View directory record Official record
Conditions
Stroke, Ischemic, Motor Activity, Upper Extremity Paralysis
Interventions
Sham, Low dose tDCS, High dose tDCS, mCIMT
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
14
States / cities
Birmingham, Alabama • Los Angeles, California • Washington D.C., District of Columbia + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2025 · Synced Oct 15, 2026, 4:42 PM EDT
Recruiting Not applicable Interventional

tDCS to Decrease Opioid Relapse (UH3)

NCT06432465
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
active tDCS, sham tDCS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional

Conditioning Neural Circuits to Improve Upper Extremity Function

NCT02611375
View directory record Official record
Conditions
Spinal Cord Injury, Tetraplegia
Interventions
transcranial direct current stimulation, peripheral nerve somatosensory stimulation, sham transcranial direct current stimulation
Other
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 15, 2026, 4:42 PM EDT
Active, not recruiting Not applicable Interventional

Pain Reduction Using NEurostimulation Study

NCT05311956
View directory record Official record
Conditions
End Stage Kidney Disease, Chronic Pain
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
21 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 15, 2026, 4:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment

NCT02596906
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
50 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Oct 15, 2026, 4:42 PM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

NCT06132412
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
transcranial direct current stimulation, physical therapy
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Oct 15, 2026, 4:42 PM EDT
Not listed Not applicable Interventional

Treatment of Tinnitus With Noninvasive Neuromodulation and Listening Therapy

NCT04934371
View directory record Official record
Conditions
Tinnitus, Subjective, Hyperacusis, Hearing Disorders
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham TDCS
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 8, 2024 · Synced Oct 15, 2026, 4:42 PM EDT