- Conditions
- Nicotine Addiction
- Interventions
- Nicotine pouch: Low dose, Nicotine pouch: High dose, Low pH, High pH
- Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 21 Years to 35 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
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Showing 1–6
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- Conditions
- Healthy Adult Participants
- Interventions
- 0 mg oral nicotine pouches, 3 mg oral nicotine pouches, 6 mg oral nicotine pouches, cigarette or e-cigarette
- Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
- Interventions
- Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine, Electronic Cigarette with no nicotine, Moist snuff, Sham Smoking, Secondhand cigarette smoke (SHS), Conditioned, filtered air, Sham Moist Snuff
- Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 81 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2021
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Tobacco Dependence
- Interventions
- 0 mg nicotine pouch, 3 mg nicotine pouch, 6 mg nicotine pouch, Smooth nicotine pouch, Wintergreen nicotine pouch
- Other
- Lead sponsor
- Milton S. Hershey Medical Center
- Other
- Eligibility
- 21 Years to 70 Years
- Enrollment
- 375 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 2
- States / cities
- Hershey, Pennsylvania • Houston, Texas
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Interventions
- Product A, Product B, Product C, Product D, Product N
- Other
- Lead sponsor
- RAI Services Company
- Industry
- Eligibility
- 21 Years to 60 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 2
- States / cities
- Raleigh, North Carolina • San Antonio, Texas
- Conditions
- Tobacco Use
- Interventions
- Test Product A, Test Product B, Test Product C, Test Product D, Test Product E, Reference Product F: Subjects' OBMST
- Other
- Lead sponsor
- Altria Client Services LLC
- Industry
- Eligibility
- 22 Years to 65 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 2
- States / cities
- Bentonville, Arkansas • Springfield, Missouri