- Conditions
- Prostate Disease, Malignancy, Benign Prostatic Hyperplasia, Prostate Cancer, Prostate Adenocarcinoma, Anxiety and Fear, Pain
- Interventions
- Self-Administered Nitrous Oxide, Oxygen
- Drug · Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years to 85 Years · Male only
- Enrollment
- 143 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.4% Sevoflurane, 0.2% sevoflurane, Placebo
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1999
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Acute Respiratory Failure
- Interventions
- Sodium Nitrite, Normal Saline
- Drug
- Lead sponsor
- Hope Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 2
- States / cities
- Tampa, Florida • Fort Worth, Texas
- Conditions
- Migraine, Pain
- Interventions
- Nitrous Oxide
- Drug
- Lead sponsor
- Children's Hospitals and Clinics of Minnesota
- Other
- Eligibility
- 8 Years to 18 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2015
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 20% N2O, 30% N2O, 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1993 – 1995
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Labor Pain
- Interventions
- Oculus Quest 2 Virtual Reality Device, Nitrous oxide
- Device · Drug
- Lead sponsor
- Brendan Carvalho
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Nitrous oxide 10% & placebo, Nitrous oxide 20% & placebo, Nitrous oxide 30% & placebo, Nitrous oxide 40% and placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1996 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Dental Anxiety
- Interventions
- Midazolam Hydrochloride 2Mg/mL Syrup, Triazolam 0.125 MG
- Drug
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 7 Years to 17 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Nitrous oxide
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1995 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% N2O, 0.2% isoflurane, 0.4% isoflurane, 100% oxygen
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Depression, Major Depressive Disorder
- Interventions
- Nitrous Oxide, Placebo
- Drug
- Lead sponsor
- Bayside Health
- Government
- Eligibility
- 18 Years and older
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Contraception, Inhalation of Nitrous Oxide
- Interventions
- In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac, Placebo pills, Oxygen, Nitrous Oxide
- Procedure · Drug · Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 21 Years and older · Female only
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 0% N2O and 10% N2O, 0% N2O and 20% N2O, 0% N2O and 30% N2O, 0% N2O and 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1995 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 0% N2O, 10% N2O, 20% N2O, 30% N2O, 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 29 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Dental Anxiety, Pain
- Interventions
- Nitrous Oxide, Midazolam
- Drug
- Lead sponsor
- Children's Hospital Colorado
- Other
- Eligibility
- 3 Years to 8 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.25 g/Kg ethanol, 0.5 g/KG ethanol, 0 g/Kg ethanol
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1997 – 1998
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.35 g/Kg ethanol, 0.7 g/Kg ethanol, 0 g/Kg ethanol
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1997 – 1999
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, Placebo, 0.2% sevoflurane, 0.4% sevoflurane, 0.6% sevoflurane
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 1998
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Rib Fracture, Rib Fracture Multiple
- Interventions
- Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block
- Device · Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 5
- States / cities
- La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more
- Conditions
- Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
- Interventions
- Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
- Drug
- Lead sponsor
- Boston Children's Hospital
- Other
- Eligibility
- 14 Years to 24 Years · Female only
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Acute Myocardial Infarction
- Interventions
- Sodium Nitrite
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 3
- States / cities
- Baltimore, Maryland • Worcester, Massachusetts
- Conditions
- Abortion in First Trimester
- Interventions
- Nitrous oxide administration
- Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 140 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Cardiovascular Abnormalities
- Interventions
- B12-Folic Acid, nitrous oxide, Nitrous oxide (NO) and placebo, Placebo, oxygen nitrogen
- Drug · Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 10% N2O, 20% N2O, 30% N2O, 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois