- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Nitrous oxide 10% & placebo, Nitrous oxide 20% & placebo, Nitrous oxide 30% & placebo, Nitrous oxide 40% and placebo
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1996 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 30
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.4% Sevoflurane, 0.2% sevoflurane, Placebo
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1996 – 1999
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 10% N2O, 20% N2O, 30% N2O, 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- Nitrous oxide
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1995 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Dental Anxiety, Pain
- Interventions
- Nitrous Oxide, Midazolam
- Drug
- Lead sponsor
- Children's Hospital Colorado
- Other
- Eligibility
- 3 Years to 8 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 15 % Nitrous oxide, 0.3 % Sevoflurane, 30% Nitrous oxide, 0.6% Sevoflurane, Placebo
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 39 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1996 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Nitrous Oxide
- Interventions
- Nitrous oxide, IV Sedation
- Drug
- Lead sponsor
- University of Arizona
- Other
- Eligibility
- 18 Years to 99 Years · Female only
- Enrollment
- 3 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, Placebo, 0.2% sevoflurane, 0.4% sevoflurane, 0.6% sevoflurane
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1997 – 1998
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.35 g/Kg ethanol, 0.7 g/Kg ethanol, 0 g/Kg ethanol
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 8 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1997 – 1999
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Labor Pain
- Interventions
- Oculus Quest 2 Virtual Reality Device, Nitrous oxide
- Device · Drug
- Lead sponsor
- Brendan Carvalho
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Pregnancy Termination in Second Trimester
- Interventions
- Nitrous Oxide, IV Saline
- Drug
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 39 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 2
- States / cities
- Denver, Colorado • Albuquerque, New Mexico
- Conditions
- Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain, Urinary Incontinence, Urinary Bladder, Overactive, Urinary Bladder, Neurogenic, Urinary Bladder Neurogenesis, Urinary Incontinence, Urge, Pelvic Floor Disorders
- Interventions
- Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection, Sham Mask
- Drug · Other
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 96 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio
- Conditions
- Headache, Tumor, Seizure Disorder, Neurofibromatoses, Hydrocephalus, Abdominal Neoplasm, Spine Deformity
- Interventions
- propofol, Dexmedetomidine, Glycopyrrolate, Lidocaine 1% Injectable Solution, Nitrous Oxide, Sevoflurane
- Drug
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 12 Months to 60 Months
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Contraception, Inhalation of Nitrous Oxide
- Interventions
- In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac, Placebo pills, Oxygen, Nitrous Oxide
- Procedure · Drug · Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 21 Years and older · Female only
- Enrollment
- 72 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Acute Myocardial Infarction
- Interventions
- Sodium Nitrite
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 3
- States / cities
- Baltimore, Maryland • Worcester, Massachusetts
- Conditions
- Abortion in First Trimester
- Interventions
- Nitrous oxide administration
- Other
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 140 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% N2O, 0.2% isoflurane, 0.4% isoflurane, 100% oxygen
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 32 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 0% N2O, 10% N2O, 20% N2O, 30% N2O, 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 29 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1994 – 1996
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- COVID-19, Acute Respiratory Distress Syndrome, Acute Respiratory Failure
- Interventions
- Sodium Nitrite, Normal Saline
- Drug
- Lead sponsor
- Hope Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 2
- States / cities
- Tampa, Florida • Fort Worth, Texas
- Conditions
- Anxiety, Dental, Dental Decay
- Interventions
- Regimen 1, Regimen #2, Regimen #3
- Combination Product
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 3 Years to 7 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Cardiovascular Abnormalities
- Interventions
- B12-Folic Acid, nitrous oxide, Nitrous oxide (NO) and placebo, Placebo, oxygen nitrogen
- Drug · Other
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Rib Fracture, Rib Fracture Multiple
- Interventions
- Cryoneurolysis, Local anesthetic peripheral nerve block, Sham Cryoneurolysis, Sham peripheral nerve block
- Device · Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 5
- States / cities
- La Jolla, California • Bethesda, Maryland • Boston, Massachusetts + 1 more
- Conditions
- Alcohol-Related Disorders, Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 0% N2O and 10% N2O, 0% N2O and 20% N2O, 0% N2O and 30% N2O, 0% N2O and 40% N2O
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 21 Years to 37 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1995 – 1997
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Opioid-Related Disorders, Substance-Related Disorders
- Interventions
- 30% Nitrous oxide, 0.25 g/Kg ethanol, 0.5 g/KG ethanol, 0 g/Kg ethanol
- Drug · Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- Not listed
- Enrollment
- 11 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 1997 – 1998
- U.S. locations
- 1
- States / cities
- Chicago, Illinois