- Conditions
- Cystic Fibrosis
- Interventions
- inhaled 7% hypertonic saline (HS)
- Drug
- Lead sponsor
- CF Therapeutics Development Network Coordinating Center
- Network
- Eligibility
- 12 Months to 30 Months
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2008
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina • Seattle, Washington
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- Conditions
- Cystic Fibrosis
- Interventions
- Absorptive clearance scan, inhaled hypertonic saline (7%), mannitol inhalation powder
- Other · Drug
- Lead sponsor
- Tim Corcoran
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Cystic Fibrosis
- Interventions
- sodium chloride (7%)
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Chapel Hill, North Carolina
- Conditions
- Cystic Fibrosis
- Interventions
- 7% NaCl, Amiloride HCl
- Drug
- Lead sponsor
- University of North Carolina
- Other
- Eligibility
- 14 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2004
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- COPD, Chronic Bronchitis
- Interventions
- tPAD, 7% hypertonic saline (510K approved as a device)
- Device
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Chronic Obstructive Pulmonary Disease, COPD, Chronic Bronchitis
- Interventions
- Inhaled 7% HS (NaCl) home treatment
- Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina