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ClinicalTrials.gov public records Last synced Oct 22, 2026, 8:02 PM EDT

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Showing 361–384 of 443 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ACT Intervention Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

An Aging Healthy Intervention for Older Adults Delivered by Community Health Workers in Senior Centers: A Clinical Trial

NCT07428174
View directory record Official record
Conditions
Healthy Aging
Interventions
aCT CHW intervention
Behavioral
Lead sponsor
George Mason University
Other
Eligibility
60 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Hazard, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Email Nudges on Plan Switching and Healthcare Utilization Among Unemployment Insurance Recipients

NCT05891418
View directory record Official record
Conditions
Health Behavior
Interventions
Two informational emails with plan information, Standard notice of eligibility determination
Behavioral
Lead sponsor
Office of Evaluation Sciences
Federal
Eligibility
0 Years to 74 Years
Enrollment
42,470 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 6, 2023 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional

Reducing Risk of Dementia Through Deprescribing

NCT04270474
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Late Onset
Interventions
Deprescribing of target anticholinergics, Usual Care
Other
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Suspended Not applicable Interventional

Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)

NCT05457790
View directory record Official record
Conditions
Sickle Cell Disease, Sickle Cell Anemia, Insomnia, Sleeplessness, Transient Insomnia, Nonorganic Insomnia, Chronic Insomnia
Interventions
ACT Intervention, Waitlist
Behavioral
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 55 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Helping Poor Smokers Quit

NCT03194958
View directory record Official record
Conditions
Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette, Smoking, Pipe, Smoking (Tobacco) Addiction, Smoking, Tobacco Use, Tobacco Dependence, Tobacco Use Cessation, Tobacco Smoking, Tobacco; Use, Rehabilitation, Nicotine Dependence, Nicotine Use Disorder, Nicotine Dependence, Cigarettes, Nicotine Dependence Tobacco Product
Interventions
Specialized Quitline, Basic Needs Navigator
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
1,944 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 22, 2026, 8:02 PM EDT
Not yet recruiting Not applicable Interventional

Feasibility, Acceptability, and Safety Trial of Brief, Breath Control-Focused Acceptance and Commitment Therapy in Adults With Chronic Cough

NCT07566117
View directory record Official record
Conditions
Chronic Cough
Interventions
Acceptance and Commitment Therapy (ACT)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Terminated Phase 1 Interventional

Ex Vivo-Activated Lymph Node Lymphocytes in Treating Patients With Stage IIIC-IV Melanoma

NCT02327390
View directory record Official record
Conditions
Stage IIIC Skin Melanoma, Stage IV Melanoma
Interventions
lymph node, X-ACT
Procedure · Biological
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 6, 2018 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional Results available

Preventing Persistent Post-Surgical Pain and Dysfunction

NCT03965897
View directory record Official record
Conditions
Pain, Function, Anxiety, Depression, Arthroplasty, Replacement, Knee, Veterans
Interventions
Acceptance and Commitment Therapy (ACT), Attention Control (AC)
Behavioral · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptive Mobile Interventions to Reduce Cancer Risk Behaviors

NCT07585357
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smartphone-based intervention messages
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 40 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional Results available

A Comparison of Three Psychoeducational Group Interventions for Veterans With Tinnitus

NCT02293512
View directory record Official record
Conditions
Tinnitus
Interventions
Coping Effectiveness Training, Cognitive-behavioral therapy, Acceptance and Commitment Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 24, 2018 · Synced Oct 22, 2026, 8:02 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers

NCT06303544
View directory record Official record
Conditions
Child Obesity
Interventions
Wedge 1
Behavioral
Lead sponsor
Alaska Native Tribal Health Consortium
Other
Eligibility
3 Years to 5 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Anchorage, Alaska
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional

Using Emails and Personalized Phone Calls to Increase Affordable Care Act Marketplace Enrollment Among Households Losing Medicaid

NCT05327712
View directory record Official record
Conditions
Health Behavior
Interventions
Control group, Email only, Phone only, Phone and email
Behavioral
Lead sponsor
Office of Evaluation Sciences
Federal
Eligibility
Not listed
Enrollment
2,173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2022 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional

Efficacy of Brief Acceptance and Commitment Therapy (ACT) for Perinatal Anxiety

NCT03837392
View directory record Official record
Conditions
Post Partum Depression, Perinatal Depression, Post Partum Anxiety, Perinatal Anxiety
Interventions
Baseline Assessment (18-26 weeks pregnant), Online Intervention and Phone Coaching Interventions, Follow Up Assessments: 34-36 weeks pregnant and 4-week postpartum, Follow Up Assessments: 8 weeks postpartum
Diagnostic Test · Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional

USC and Bodyport Remote Heart Failure Management Study

NCT04975633
View directory record Official record
Conditions
Heart Failure
Interventions
Bodyport Cardiac Scale
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 26, 2025 · Synced Oct 22, 2026, 8:02 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Blood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act Bold

NCT03821948
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Not listed
Lead sponsor
Exact Sciences Corporation
Industry
Eligibility
40 Years and older
Enrollment
5,131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
40
States / cities
Tempe, Arizona • Chula Vista, California • Huntington Beach, California + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Phase 3 Interventional

Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation

NCT01873352
View directory record Official record
Conditions
Atrial Fibrillation, Hypertension
Interventions
catheter ablation, renal sympathetic denervation
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 75 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Short Hills, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 4, 2019 · Synced Oct 22, 2026, 8:02 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients

NCT02338947
View directory record Official record
Conditions
Frail Elderly, Coronary Artery Disease
Interventions
Off-pump coronary-artery bypass grafting, On-pump coronary-artery bypass grafting
Other
Lead sponsor
University of Sao Paulo General Hospital
Other
Eligibility
60 Years and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Phase 1 Interventional

Reducing Aggression in Children and Adolescent on an Inpatient Unit

NCT01377948
View directory record Official record
Conditions
Anger, Aggression
Interventions
ACT with RAGE-Control
Behavioral
Lead sponsor
Gonzalez-Heydrich, Joseph, M.D.
Individual
Eligibility
8 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2012 · Synced Oct 22, 2026, 8:02 PM EDT
Withdrawn Not applicable Interventional

Culturally Tailored ACT for Black Trauma

NCT06296030
View directory record Official record
Conditions
Stress Disorders, Traumatic, Anxiety, Anxiety Disorders
Interventions
POOF ACT program, Classic ACT program
Behavioral
Lead sponsor
Azusa Pacific University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Azusa, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2024 · Synced Oct 22, 2026, 8:02 PM EDT
Terminated Not applicable Interventional Results available

Medihoney and Santyl for Burn Injuries

NCT02250183
View directory record Official record
Conditions
Burns
Interventions
MEDIHONEY® GEL WITH ACTIVE LEPTOSPERMUM HONEY, Santyl
Device
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 22, 2026, 8:02 PM EDT
Completed No phase listed Observational

Lactation Outcomes Among Survivors of Pediatric Cancer

NCT02399956
View directory record Official record
Conditions
Cancer, Leukemia
Interventions
Survey
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
471 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Oct 22, 2026, 8:02 PM EDT
Active, not recruiting Not applicable Interventional

Pain and Opioids: Integrated Treatment In Veterans

NCT04648228
View directory record Official record
Conditions
Chronic Pain, Opioid-use Disorder, Opioids; Harmful Use
Interventions
ACT+MBRP, Education control
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
21 Years to 75 Years
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
San Francisco, California • Albuquerque, New Mexico • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 22, 2026, 8:02 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Secretome Treatment for Facial Rejuvenation

NCT07227883
View directory record Official record
Conditions
Facial Aging, Rejuvenation, Stem Cell, Stem Cell Banking
Interventions
Autologous Hair Follicle-Derived Secretome, Control Saline
Other
Lead sponsor
Acorn Biolabs Inc.
Industry
Eligibility
30 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Newport Beach, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 22, 2026, 8:02 PM EDT
Completed Not applicable Interventional

A Guided Online ACT Intervention Combined With Psychoeducation for People With Spinal Cord Injury

NCT04670406
View directory record Official record
Conditions
Spinal Cord Injuries, Psychological Distress
Interventions
acceptance and commitment therapy (ACT) combined with psychoeducation
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Oct 22, 2026, 8:02 PM EDT