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ClinicalTrials.gov public records Last synced Oct 4, 2026, 5:28 PM EDT

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Showing 25–45 of 45 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: ACUVUE Oasys 1-Day Clear all
Withdrawn Not applicable Interventional

A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses

NCT02298400
View directory record Official record
Conditions
Contact Lens Complication
Interventions
Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
Device
Lead sponsor
ORA, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Effect of Scatter on Visual Performance

NCT07443215
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE® OASYS 1-Day Sphere, ACUVUE® OASYS Multifocal
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Results available

Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Toric Contact Lenses

NCT05959200
View directory record Official record
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 29, 2024 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE® OASYS 1-Day for Astigmatism Contact Lenses With Alternative Lidstock

NCT05713552
View directory record Official record
Conditions
Ocular Physiology
Interventions
Acuvue Oasys 1 Day for Astigmatism with Legacy lidstock, Acuvue Oasys 1 Day for Astigmatism with Amcor laminated lidstock
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Daily Disposable Toric Soft Lenses Manufactured With an Alternative Hydration Process

NCT06967129
View directory record Official record
Conditions
Astigmatism
Interventions
Investigational daily disposable, soft, toric lenses manufactured on 4th Generation Technology (4GT) lines with extended mini-stack hydration using propylene glycol (PG) as the hydration solvent., ACUVUE® Oasys 1-Day for Astigmatism (AO1DfA) soft contact lenses manufactured on 3rd Generation Technology (3GT) legacy lines using isopropyl alcohol (IPA) as the hydration solvent.
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
281 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
20
States / cities
Mission Viejo, California • San Diego, California • Jacksonville, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Results available

Product Performance of a New Silicone Hydrogel Contact Lens

NCT04901897
View directory record Official record
Conditions
Myopia
Interventions
kalifilcon A, delefilcon A, senofilcon A
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years to 40 Years
Enrollment
805 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
35
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Azusa, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2021 · Synced Oct 4, 2026, 5:28 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of ACUVUE® OASYS MAX 1-Day Multifocal and DAILIES® AquaComfort Plus® Multifocal

NCT07788521
View directory record Official record
Conditions
Visual Acuity
Interventions
Senofilcon A, Nelfilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
11
States / cities
Longwood, Florida • Roswell, Georgia • St Louis, Missouri + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses

NCT04968925
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Precision 1
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
10
States / cities
Mission Viejo, California • Maitland, Florida • Orange Park, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Approved Contact Lenses

NCT07174596
View directory record Official record
Conditions
Visual Acuity
Interventions
B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
4
States / cities
Roswell, Georgia • New Bremen, Ohio • Salem, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Contact Lenses With UV/HEV-Filter on Visual Function

NCT05601544
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal, ACUVUE OASYS MAX 1-Day Multifocal, ACUVUE OASYS 1-Day for Astigmatism, senofilcon A based contact lens (toric) with new UV/HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Results available

Two Daily Disposable Contact Lenses in Symptomatic Patients

NCT03628599
View directory record Official record
Conditions
Myopia
Interventions
Delefilcon A contact lenses, Senofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Bloomington, Illinois • Pittsburg, Kansas • Powell, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ocular Characteristics in Contact Lens and Spectacle Wear

NCT03913377
View directory record Official record
Conditions
Visual Acuity
Interventions
Spectacles, ACUVUE OASYS®1-Day with HydraLuxe™ Technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 42 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
3
States / cities
Jacksonville, Florida • Longwood, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Role of Glare and Spectral Filtering on Contrast Sensitivity: A Pilot Study

NCT05582304
View directory record Official record
Conditions
Visual Acuity
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Delefilcon A and Senofilcon A Daily Disposable Toric Soft Contact Lenses Over One Week of Wear

NCT06749496
View directory record Official record
Conditions
Astigmatism
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of Spherical Soft Contact Lenses, Toric Soft Contact Lenses and Spectacles in Low Astigmats

NCT05056870
View directory record Official record
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day with HydraLuxe Technology for Astigmatism, ACUVUE Oasys 1-Day with HydraLuxe Technology
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
13
States / cities
Rocklin, California • Longwood, Florida • Maitland, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PAVES Benchmarking Pilot Study of Daily Disposable Contact Lenses

NCT04032457
View directory record Official record
Conditions
Refractive Errors
Interventions
Phase A - olifilcon B with Tangible Coatings, Phase B - etafilcon A with Tangible Coatings
Device
Lead sponsor
Vision Service Plan
Industry
Eligibility
18 Years to 42 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Atlanta, Georgia • Niles, Illinois • Carmel, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Wear Experience With a Daily Disposable Contact Lens

NCT04296877
View directory record Official record
Conditions
Contact Lens
Interventions
Daily Disposable Contact Lens
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Visual Performance of Senofilcon A With and Without a New UV/HEV-filter

NCT05021081
View directory record Official record
Conditions
Visual Performance
Interventions
TRP-200, ACUVUE Oasys 1-Day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients

NCT00799422
View directory record Official record
Conditions
Conjunctival Staining
Interventions
Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2012 · Synced Oct 4, 2026, 5:28 PM EDT
Completed Not applicable Interventional Results available

ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®

NCT02750813
View directory record Official record
Conditions
Refractive Error
Interventions
Delefilcon A contact lenses, Senofilcon A contact lenses
Device
Lead sponsor
Alcon, a Novartis Company
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 4, 2026, 5:28 PM EDT