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ClinicalTrials.gov public records Last synced Oct 18, 2026, 11:15 PM EDT

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Showing 145–168 of 190 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: AF Ablation Clear all
Completed Not applicable Interventional Results available

STOP AF First: Cryoballoon Catheter Ablation in an Antiarrhythmic Drug Naive Paroxysmal Atrial Fibrillation

NCT03118518
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Fibrillation New Onset
Interventions
Cryoablation, Antiarrhythmic drug
Device · Drug
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 80 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
24
States / cities
Birmingham, Alabama • Anchorage, Alaska • Newport Beach, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Not listed Phase 2 Interventional

Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI

NCT01959997
View directory record Official record
Conditions
Atrial Fibrillation, Arterial Hypertension
Interventions
Redo PVI, PVI + RDN
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Phase 3 Interventional

Concomitant Treatment of Permanent Atrial Fibrillation

NCT00566787
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Surgical bipolar radiofrequency ablation using the AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
10
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • Grand Rapids, Michigan + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2012 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Phase 4 Interventional Results available

Oral Steroids Before Pulmonary Vein Isolation to Improve Outcomes

NCT01206452
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Prednisone, Placebo, Ablation Procedure
Drug · Other · Procedure
Lead sponsor
Dhanunjaya Lakkireddy, MD, FACC
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 17, 2017 · Synced Oct 18, 2026, 11:15 PM EDT
Active, not recruiting Not applicable Interventional

Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation

NCT04922281
View directory record Official record
Conditions
Atrial Fibrillation, Cardiovascular Diseases, Heart Diseases, Arrhythmias, Cardiac, Pathologic Processes
Interventions
Insertable Cardiac Monitor or external non-invasive LT-ECG patch
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Terminated Not applicable Interventional

Efficacy and Safety Study of the Estech COBRA® Surgical System to Treat Patients With a History of Irregular Heart Beats

NCT01683045
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
The Estech COBRA® Surgical System
Device
Lead sponsor
Endoscopic Technologies, Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
13
States / cities
Mesa, Arizona • Hartford, Connecticut • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 23, 2014 · Synced Oct 18, 2026, 11:15 PM EDT
Active, not recruiting No phase listed Observational

P-wave Duration and Local Potential as Predictors of AF Recurrence Following Pulmonary Vein Isolation

NCT07471308
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Fibrillation Patients Treated With the FARAPULSE™ PFA System, Atrial Fibrillation (Paroxysmal), Pulmonary Vein Isolation
Interventions
AF Recurrence RIsk Assessment post pulmonary vein isolation
Device
Lead sponsor
CathVision ApS
Industry
Eligibility
21 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 18, 2026, 11:15 PM EDT
Recruiting No phase listed Observational

PULSED AF Post-Approval Study

NCT06578104
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
PulseSelect™ PFA system
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
580 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
19
States / cities
Tampa, Florida • Atlanta, Georgia • Chicago, Illinois + 15 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional Results available

Irrigated Ablation System Evaluation for Atrial Fibrillation (AF)

NCT01056328
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
SJM Irrigated Cardiac Ablation System, FDA approved Open Irrigated RF Ablation System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
27
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 22 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional

Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF

NCT02456233
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Conventional AF Ablation with PVI, FIRM-guided ablation plus PVI
Procedure
Lead sponsor
Stanford University
Other
Eligibility
22 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
2
States / cities
San Diego, California • Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional Results available

iPhone Helping Evaluate Atrial Fibrillation Rhythm Through Technology

NCT02731326
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
AliveCor, Behavioral Altering Messaging
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 18, 2026, 11:15 PM EDT
Not listed No phase listed Observational

Dielectric Tissue Imaging in Cavotricuspid Isthmus Ablation

NCT04438395
View directory record Official record
Conditions
Atrial Fibrillation and Flutter
Interventions
Cardiac ablation via catheter
Device
Lead sponsor
EPD Solutions, A Philips Company
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Delayed Enhancement MRI-Guided Ablation vs Conventional Catheter Ablation of Atrial Fibrillation

NCT02529319
View directory record Official record
Conditions
Atrial Fibrillation, Fibrosis
Interventions
MRI-Guided Ablation, Conventional Ablation
Procedure
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
843 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 18, 2026, 11:15 PM EDT
Completed No phase listed Observational

Ten-year Outcomes After AF Ablation

NCT01867099
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Valley Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
445 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2012
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 18, 2026, 11:15 PM EDT
Completed No phase listed Observational

Evaluating the Performance of the KODEX-EPD CRyOballoon Occlusion Feature in Patients With Atrial Fibrillation

NCT04293198
View directory record Official record
Conditions
Atrium; Fibrillation, Ablation
Interventions
KODEX-EPD System, Fluoroscopy with contrast dye
Device
Lead sponsor
EPD Solutions, A Philips Company
Industry
Eligibility
18 Years to 120 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 18, 2026, 11:15 PM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of Pulmonary Vein isOLation And posterioR Wall Ablation wIth pulSed Field Energy in Patients With Paroxysmal and Persistent AF

NCT06099730
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulsed Field Ablation (PFA)
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
6
States / cities
Jonesboro, Arkansas • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 18, 2026, 11:15 PM EDT
Recruiting No phase listed Observational

Clinical and Healthcare Outcomes From Real-World Use in the United States of a Companion AI During AF Ablation

NCT06056271
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
AF Ablation
Device
Lead sponsor
Volta Medical
Industry
Eligibility
21 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Evanston, Illinois • Overland Park, Kansas • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional Results available

Assessing Arrhythmias After Ablation Using Implantable Recorders

NCT01176617
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Reveal XT implantable loop recorder
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 18, 2026, 11:15 PM EDT
Completed Not applicable Interventional Results available

Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study (STOP AF PAS)

NCT01456949
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation (PAF)
Interventions
Medtronic Arctic Front® Cardiac CryoAblation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
32
States / cities
Anchorage, Alaska • Phoenix, Arizona • San Jose, California + 28 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Enrolling by invitation No phase listed Observational

Health eHeart BEAT-AFib - Health eHeart Biomarkers of Early Atrial Transformation in Atrial Fibrillation

NCT04404465
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2040
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 18, 2026, 11:15 PM EDT
Completed No phase listed Observational

DECAAF: Delayed-Enhancement MRI (DE-MRI) Determinant of Successful Radiofrequency Catheter Ablation of Atrial Fibrillation

NCT01150214
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
DE-MRI
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
339 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
5
States / cities
Tampa, Florida • Chicago, Illinois • Columbus, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2017 · Synced Oct 18, 2026, 11:15 PM EDT
Not listed Phase 2 Interventional

Sole-Therapy Treatment of Atrial Fibrillation

NCT00566176
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Surgical Ablation using the AtriCure Bipolar System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
5
States / cities
Tampa, Florida • Cincinnati, Ohio • Oklahoma City, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2013 · Synced Oct 18, 2026, 11:15 PM EDT
Active, not recruiting No phase listed Observational

Real-world Safety and Effectiveness Registry of Catheter Ablation of Paroxysmal Atrial Fibrillation as Initial Control Therapy With the Thermocool SmartTouch SF Catheter (A Sub-study of REAL AF Registry)

NCT07092774
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation (PAF)
Interventions
Ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Birmingham, Alabama • Ventura, California • Jacksonville, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 18, 2026, 11:15 PM EDT
Recruiting No phase listed Observational

Observational Study to Examine the Procedural and Outcomes of AF Ablation Assisted by STAR Apollo™ Mapping System

NCT05826665
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
Persistent AF ablation assisted with the STAR Apollo Mapping System
Other
Lead sponsor
Kansas City Heart Rhythm Research Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
Jonesboro, Arkansas • Sarasota, Florida • Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Oct 18, 2026, 11:15 PM EDT