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Conditions: Cancer, Chronic Stress, Autonomic Dysfunction
Interventions: Hight intensity interval training, Cyclic Hyperventilation with Retention; Behavioral
Lead sponsor: University of Northern Colorado; Other
Eligibility: 18 Years to 50 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Greeley, Colorado

Conditions: Sleep Disordered Breathing (SDB), Sleep Apnea
Interventions: SSAM, Polysomnography, EnsoSleep; Device · Diagnostic Test
Lead sponsor: Pathway Medtech, LLC.; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 3
States / cities: Burlingame, California • Irvine, California • La Jolla, California

Conditions: Diabetes Complications, Diabetic Neuropathies
Interventions: Muscle power, balance perturbation, aerobic exercise; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 55 Years to 80 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions: HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention; Other · Behavioral
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 148 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Obesity, Pre-hypertension, Hypertension
Interventions: Resistance exercise training, Hypocaloric diet, Resistance exercise training & diet; Other
Lead sponsor: Florida State University; Other
Eligibility: 40 Years to 65 Years · Female only
Enrollment: 41 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Schizophrenia
Interventions: I-CAT Therapy; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Female Sexual Arousal Disorder
Interventions: HRV Biofeedback, Autogenic Training; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Multiple Sclerosis, Fatigue
Interventions: 4-week Relaxation Training, 4-week Behavioral Activation, 4-week Cognitive Therapy; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Obesity
Interventions: Unloaded-Whole Body Vibration (WBVT), Loaded-Whole Body Vibration (WBVT); Other
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 25 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Persistent Post-concussive Symptoms, Post Traumatic Headache
Interventions: SPINEPASS Physical Therapy, Standard Physical Therapy; Other
Lead sponsor: The University of Queensland; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Vascular Health, Autonomic Function
Interventions: Endurance Exercise; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 18 Years to 35 Years
Enrollment: 91 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Posttraumatic Stress Disorder, Pseudopheochromocytoma, Healthy Volunteers, Neurocardiogenic Syncope, Postural Tachycardia Syndrome
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 2 Years and older
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2021
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Type 2 Diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus in Obese
Interventions: Aerobic exercise training; Other
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 40 Years to 70 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Pelvic Pain
Interventions: Pain Neuroscience Education, Lumbopelvic and Hip Therapeutic Exercise, Extrapelvic Manual Therapy, Extrapelvic Dry Needling, Deep Paced Diaphragmatic Breathing Training, Chronic Pelvic Pain Education, Intravaginal and intrarectal pelvic floor physical therapy; Other
Lead sponsor: Baylor University; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 2
States / cities: San Antonio, Texas • Waco, Texas

Conditions: Obesity, Pre-hypertension, Hypertension
Interventions: Whole Body Vibration Training, Hypocaloric diet, Whole body vibration training & diet; Other
Lead sponsor: Florida State University; Other
Eligibility: 45 Years to 65 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Premature Birth, Obstetric Labor, Premature
Interventions: Welch Emotional Connection Screen for Neonatal Intensive Care Unit, NICU WECS Training; Behavioral · Other
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 193 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Ridgewood, New Jersey

Conditions: Dysautonomia, Anxiety, Depression
Interventions: Transdiagnostic Group-Based Treatment; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 13 Years to 18 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Traumatic Brain Injury
Interventions: OSC-; Behavioral
Lead sponsor: Brigham Young University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Provo, Utah

Conditions: Concussion, Mild
Interventions: Targeted Multidomain, Behavioral Management; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 49 Years
Enrollment: 169 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania • Fairfax, Virginia

Conditions: Stress, Stress, Psychological, Stress, Physiological, Anxiety, Mental Well Being, Happiness, Resilience
Interventions: SKY; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 21 Years to 99 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: San Diego, California

Conditions: Alcohol Use Disorder
Interventions: Cervical transcutaneous vagus nerve stimulation (active comparator), Cervical transcutaneous vagus nerve stimulation (sham comparator); Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: San Diego, California

Conditions: Irritable Bowel Syndrome (IBS)
Interventions: CBT/ Hypnotherapy, Routine Management; Behavioral · Drug
Lead sponsor: Seton Healthcare Family; Other
Eligibility: 8 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Pulmonary Disease, Autonomic Dysfunction, COPD
Interventions: Meditative Movement taught via DVD; Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: Not listed
Enrollment: 220 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Lebanon, New Hampshire

Conditions: Spinal Cord Injury
Interventions: Epidural Stimulator; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years to 65 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Rochester, Minnesota

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Can You Breathe Your Way To Better Health?

Detection of Sleep Stages and Arousals Using Neural Network Classifiers

Enhance Balance and Mobility in People With Type 2 Diabetic Peripheral Neuropathy

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

Low-intensity Resistance Exercise and Diet on Arterial Function and Blood Pressure

Integrated Coping and Awareness Training

Heart Rate Variability Biofeedback for Female Sexual Arousal Disorder

Prospective Case Series to Refine Standalone Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue

Whole Body Vibration and External Load Exercise Training on Cardiovascular and Autonomic Function in Obese Individuals

SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.

Vascular and Neuro-inflammatory Effects of Endurance Exercise Training in African Americans

Clinical Autonomic Disorders: A Training Protocol

Heart Rate Variability-Guided Exercise Training in Type 2 Diabetes

Conservative Care for Pelvic Pain (C2P2) in Women Service Members

Diet and Whole-body Vibration Training on Cardiovascular and Autonomic Function

Welch Emotional Connection Screen (WECS) in the NICU

Implementation of Transdx Group for POTS

Heart Rate Variability Biofeedback Following Traumatic Brain Injury

Targeted Multidomain (T-MD) Interventions for Complex Mild Traumatic Brain Injury (mTBI)

The Effect of SKY Breath Meditation on Health and Well-being

Non-invasive Vagal Nerve Stimulation as Novel Treatment to Improve Functional Outcomes in Veterans With Alcohol Use Disorder

Collaborative Cognitive Behavioral Therapy / Hypnotherapy for Treatment of Pediatric Functional Gastrointestinal Disease

Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants

Spinal Cord Injury Epidural Stimulation