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ClinicalTrials.gov public records Last synced Oct 20, 2026, 6:03 AM EDT

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Showing 25–48 of 255 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Ablation for atrial fibrillation. Clear all
Terminated Not applicable Interventional

Renal Denervation Therapy in Hypertensive Patients Undergoing A-Fib Ablation

NCT01952743
View directory record Official record
Conditions
Atrial Fibrillation, Hypertension
Interventions
AF ablation with Renal Denervation, AF ablation alone
Procedure
Lead sponsor
Siva Mulpuru
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Phase 3 Interventional

Cryoballoon Ablation of Pulmonary Veins After Failed RF Ablation in Patients With Paroxysmal AF

NCT01611701
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
cryoballoon ablation, Radiofrequency ablation
Procedure
Lead sponsor
Meshalkin Research Institute of Pathology of Circulation
Network
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 5, 2012 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Phase 4 Interventional

Ablation vs Amiodarone for Treatment of AFib in Patients With CHF and an ICD

NCT00729911
View directory record Official record
Conditions
Heart Failure
Interventions
Atrial Fibrillation ablation, Amiodarone
Procedure · Drug
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years and older
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 20, 2026, 6:03 AM EDT
Active, not recruiting No phase listed Observational

REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry

NCT06354777
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Atrial Ablation
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
6
States / cities
Chandler, Arizona • Indianapolis, Indiana • Royal Oak, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL)

NCT03057548
View directory record Official record
Conditions
Atrial Fibrillation Chronic, Persistent Atrial Fibrillation
Interventions
Cryo or Radiofrequency (RF) Ablation only of Pulmonary Veins, Cryo or RF Ablation of Pulmonary Veins plus Ablation of the PLAW
Procedure
Lead sponsor
Arash Aryana, MD
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 20, 2026, 6:03 AM EDT
Completed No phase listed Observational

Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation

NCT00571597
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Not listed
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 85 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2014 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Ablation vs Drug Therapy for Atrial Fibrillation - Pilot Trial

NCT00578617
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmia
Interventions
Rate Control, Ablation Therapy, Rhythm control
Drug · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
10
States / cities
Birminham, Alabama • Los Angeles, California • Maywood, Illinois + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2013 · Synced Oct 20, 2026, 6:03 AM EDT
Terminated Not applicable Interventional

Necessity of Anti-Arrhythmic Medication After Surgical Ablation for Atrial Fibrillation

NCT01416935
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
No Amiodarone
Other
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Jan 20, 2022 · Synced Oct 20, 2026, 6:03 AM EDT
Recruiting Not applicable Interventional

CellFX® Nanosecond Pulsed Field Ablation (nsPFA)™ Cardiac Surgery Clamp System to Treat Atrial Fibrillation

NCT06959121
View directory record Official record
Conditions
Atrial Fibrillation, Maze Procedure, AF, Ablation
Interventions
CellFX® nsPFA™ Cardiac Surgery System
Device
Lead sponsor
Pulse Biosciences, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
St. Helena, California • Orlando, Florida • Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

TactiFlex Paroxysmal Atrial Fibrillation IDE Trial

NCT04356040
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
TactiFlex SE, TactiFlex SE - High Standard Power
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 99 Years
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
30
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 26 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Phase 4 Interventional Results available

DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation

NCT02666742
View directory record Official record
Conditions
Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
Interventions
DOAC, Aspirin
Drug
Lead sponsor
Kansas City Heart Rhythm Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
4
States / cities
Kansas City, Kansas • Overland Park, Kansas • The Bronx, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 22, 2022 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Continued Access Protocol

NCT00889681
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Arctic Front Cardiac Cryoablation System
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
10
States / cities
Phoenix, Arizona • Los Angeles, California • Stanford, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Oct 20, 2026, 6:03 AM EDT
Terminated Not applicable Interventional Results available

CONcomitant eValuation of Epicor Left atRial Therapy for AF

NCT00519194
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Epicor LP Cardiac Ablation System, Surgical ablation of permanent AF
Device · Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
15
States / cities
Fresno, California • Bradenton, Florida • Pensacola, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 20, 2026, 6:03 AM EDT
Not listed Not applicable Interventional

Comparison of Two Pulmonary Vein Ablation Techniques for Persistent AF

NCT03295422
View directory record Official record
Conditions
Chronic Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
RF ablation PVI alone, RF ablation PVI plus LPAW
Procedure
Lead sponsor
Sequoia Hospital
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 20, 2026, 6:03 AM EDT
Completed No phase listed Observational Results available

EnSite Precision Observational Study

NCT03260244
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
cardiac mapping and radiofrequency ablation procedure
Procedure
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,065 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
7
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • Little Rock, Arkansas + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 20, 2026, 6:03 AM EDT
Withdrawn Phase 4 Interventional

Catheter Ablation for Recently Diagnosed Paroxysmal Atrial Fibrillation

NCT01505296
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Antiarrhythmic drug, Catheter ablation
Drug · Procedure
Lead sponsor
Valley Health System
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Ridgewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 20, 2026, 6:03 AM EDT
Completed No phase listed Observational Results available

Comparison of Intracardiac Echocardiography and Transesophageal Echocardiography

NCT02213666
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Flutter
Interventions
Intracardiac Imaging
Device
Lead sponsor
Elad Anter
Other
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Phase 4 Interventional Results available

Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial Fibrillation

NCT03140631
View directory record Official record
Conditions
Atrial Fibrillation, Catheter Ablation
Interventions
Protamine Sulfate
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 23, 2018 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional

One More Magnetic Resonance Imaging

NCT02293070
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Delayed Enhanced Cardiac Magnetic Resonance Imaging, Cryoablation
Other · Procedure
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional

A Study of the TactiFlex SE Catheter and Volt PFA Generator in Subjects With PAF:

NCT06676072
View directory record Official record
Conditions
Atrial Fibrillation (AF), Atrial Arrhythmia, Paroxysmal AF, Drug Refractory Paroxysmal Atrial Fibrillation
Interventions
PFA Ablation catheter
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
29
States / cities
Scottsdale, Arizona • Little Rock, Arkansas • Stanford, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 20, 2026, 6:03 AM EDT
Recruiting No phase listed Observational

Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA

NCT07275151
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary vein isolation ablation
Device
Lead sponsor
CathVision ApS
Industry
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Ypsilanti, Michigan • Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 20, 2026, 6:03 AM EDT
Terminated Not applicable Interventional Results available

Investigational Device Exemption (IDE) Study for the Approval of Closed Loop Stimulation (CLS) and Cardiac Resyncronization Pacing Therapies (CRT) for the Treatment of Atrial Fibrillation (AF) With Ablate and Pace

NCT00356057
View directory record Official record
Conditions
Atrial Fibrillation, Congestive Heart Failure
Interventions
Protos DR/CLS and Stratos LV CRT pacemakers
Device
Lead sponsor
Biotronik, Inc.
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
10
States / cities
Birmingham, Alabama • Lake Charles, Louisiana • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2018 · Synced Oct 20, 2026, 6:03 AM EDT
Active, not recruiting Not applicable Interventional

Pulsed-Field Ablation With/Without Electrogram Mapping

NCT07541989
View directory record Official record
Conditions
Non-paroxysmal Atrial Fibrillation
Interventions
PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates, PFA-based PVI+PWI alone
Procedure
Lead sponsor
Xu Liu
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 20, 2026, 6:03 AM EDT
Completed Not applicable Interventional Results available

Assessing Arrhythmias After Ablation Using Implantable Recorders

NCT01176617
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Reveal XT implantable loop recorder
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 20, 2026, 6:03 AM EDT