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ClinicalTrials.gov public records Last synced Oct 16, 2026, 4:14 PM EDT

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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Abstinence from alcohol Clear all
Completed Phase 4 Interventional

Study of Aripiprazole in Subjects With Alcoholism

NCT00082199
View directory record Official record
Conditions
Alcoholism
Interventions
Aripiprazole, Placebo
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
14
States / cities
Farmington, Connecticut • New Haven, Connecticut • Indianapolis, Indiana + 11 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2013 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse

NCT00585780
View directory record Official record
Conditions
Alcohol Dependence
Interventions
Prazosin Tablet, Placebo Tablet
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Oct 16, 2026, 4:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Mapping Brain Glutamate in Humans: Sex Differences in Cigarette Smokers

NCT05279053
View directory record Official record
Conditions
Sex, Cigarette Smoking
Interventions
Abstinence and Smoking
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 45 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Withdrawn Phase 2 Interventional

Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons

NCT01853293
View directory record Official record
Conditions
Alcohol Abuse, Alcohol Dependence, Heavy Drinking Days
Interventions
Kudzu extract, Placebo, Medical Management
Drug · Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
21 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 7, 2015 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional Results available

Financial Incentives, Randomization With Stepped Treatment Trial

NCT03089320
View directory record Official record
Conditions
Unhealthy Alcohol Use
Interventions
Contingency Management Counseling, Addiction Physician Management, Motivational Enhancement Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
7
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Phase 4 Interventional Results available

Sertraline Pharmacotherapy for Alcoholism Subtypes

NCT00368550
View directory record Official record
Conditions
Alcoholism
Interventions
Sertraline, Placebo
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 21, 2011 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional

Chronic Alcohol, Stress Inflammatory Response and Relapse Risk

NCT02193204
View directory record Official record
Conditions
Alcohol Dependence, Depressive Symptomatology
Interventions
Personal Stress Imagery, Neutral Imagery
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional

Adapting Alcohol Behavioral Couple Therapy for Service Members in Post-Deployment

NCT03589521
View directory record Official record
Conditions
Alcohol Abuse
Interventions
ABCT_Military
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Virtual Incentive Treatment for Alcohol

NCT06265506
View directory record Official record
Conditions
Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
Interventions
Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated May 30, 2025 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional

Contingency Management for Alcohol Use Disorder

NCT03701204
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
DynamiCare Rewards
Behavioral
Lead sponsor
DynamiCare Health
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Centerville, Massachusetts • Falmouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Reducing Cardiovascular Risks: The Role of Alcohol Use

NCT07783061
View directory record Official record
Conditions
Alcohol Drinking, Drinking Behavior, At-risk Drinking, Cardiovascular Risk Factor, High Blood Pressure
Interventions
Alcohol Abstinence, Control arm
Behavioral · Other
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
26 Years to 49 Years
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional

fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults

NCT01320748
View directory record Official record
Conditions
Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use, Relapse
Interventions
Dual Processing, Relapse Prevention
Behavioral
Lead sponsor
Inova Health Care Services
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 30, 2018 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional Results available

Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder

NCT03987581
View directory record Official record
Conditions
Alcohol Drinking, Veterans
Interventions
Cognitive Behavioral Therapy (CBT), Mobile Contingency Management (mCM), Long-term incentive
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Not listed Not applicable Interventional

Harm Reduction Talking Circles for American Indians and Alaska Natives With Alcohol Use Disorders

NCT04267692
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
HaRTC
Other
Lead sponsor
Washington State University
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Phase 2Phase 3 Interventional

Integrated Digital Intervention for Alcohol Use Disorder

NCT05748639
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Mobile health application, Medical Management
Other
Lead sponsor
Quit Genius
Industry
Eligibility
18 Years and older
Enrollment
242 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Oct 16, 2026, 4:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Averting NAS Among Opioid-Using Young Women Receiving MAT Using Buprenorphine

NCT04611659
View directory record Official record
Conditions
Opioid-use Disorder, Contraception, Neonatal Abstinence Syndrome
Interventions
Motivational Interviewing and Educational Training (MIET)
Behavioral
Lead sponsor
Meharry Medical College
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Phase 4 Interventional Results available

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

NCT02995915
View directory record Official record
Conditions
Smoking Cessation, Alcohol Drinking
Interventions
Nicotine Replacement Therapy, Bupropion, Cognitive Behavioral Treatment, Mobile Contingency Management, Mobile Monitoring
Other · Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 28, 2021 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Sex Differences in the Response to Abstinence From Alcohol.

NCT03827460
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Abstinence from alcohol, Usual drinking, Intravenous Alcohol
Behavioral · Drug
Lead sponsor
Indiana University
Other
Eligibility
21 Years to 35 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Active, not recruiting Not applicable Interventional

Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support

NCT05473598
View directory record Official record
Conditions
Alcoholism
Interventions
Stand Down app, Peer-Supported Stand Down, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Palo Alto, California • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

NCT05522075
View directory record Official record
Conditions
Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence, Aging, Lifestyle Factors, Vasodilation, Behavioral Problem
Interventions
Exercise Training, Alcohol Abstinence Intervention
Behavioral
Lead sponsor
The University of Texas at Arlington
Other
Eligibility
50 Years to 64 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Post-ablation Alcohol Impacts Arrhythmia Recurrence, Quality of Life and Cognition in AF

NCT05510167
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Study arm
Behavioral
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 85 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional

Intervention Targeting Substance Using Older Adults With HIV

NCT01305629
View directory record Official record
Conditions
HIV, Medication Adherence, Substance Dependence
Interventions
Spiritual Self-Schema Therapy
Behavioral
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
50 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2016 · Synced Oct 16, 2026, 4:14 PM EDT
Recruiting Not applicable Interventional

Reset Challenge: Reducing High-risk Drinking for Cancer Prevention

NCT07591428
View directory record Official record
Conditions
Alcohol Drinking, Heavy Drinking, Binge Drinking
Interventions
30-Day Alcohol Abstinence Challenge
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 120 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 16, 2026, 4:14 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phosphatidylethanol-Based Contingency Management for Housing

NCT04038021
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Phosphatidylethanol-based Contingency Management, Non-Contingent Control
Behavioral
Lead sponsor
Washington State University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 16, 2026, 4:14 PM EDT