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Conditions: Breast Cancer
Interventions: Radiation Therapy; Radiation
Lead sponsor: GenesisCare USA; Other
Eligibility: 50 Years to 100 Years · Female only
Timeline: 2021 – 2024
U.S. locations: 1
States / cities: Stuart, Florida

Conditions: Breast Cancer
Interventions: Brachytherapy APBI, 3D-CRT (photon) APBI, Proton APBI; Radiation
Lead sponsor: Mayo Clinic; Other
Eligibility: 50 Years and older · Female only
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 3
States / cities: Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota

Conditions: Breast Carcinoma, Breast Cancer, Stage 0 Breast Cancer, Stage I Breast Cancer
Interventions: External Beam Accelerated Partial Breast Irradiation; Radiation
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 50 Years and older · Female only
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2029
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Breast Cancer
Interventions: Phase II - Preoperative Radiation followed by Lumpectomy.; Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older · Female only
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2018
U.S. locations: 3
States / cities: Baltimore, Maryland • Columbia, Maryland • Glen Burnie, Maryland

Conditions: Breast Cancer, Breast Cancer Female, Breast Adenocarcinoma
Interventions: Standard of Care Schedule Variation: SABR, Breast-conserving Surgery; Other · Procedure
Lead sponsor: H. Lee Moffitt Cancer Center and Research Institute; Other
Eligibility: 50 Years and older · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Breast Cancer
Interventions: brachytherapy; Radiation
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 151 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2013
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Breast Cancer, Long-term Effects Secondary to Cancer Therapy in Adults, Skin Reactions Secondary to Radiation Therapy
Interventions: adjuvant therapy, conventional surgery, 3-dimensional conformal radiation therapy, brachytherapy, intracavitary balloon brachytherapy, proton beam radiation therapy; Procedure · Radiation
Lead sponsor: Abramson Cancer Center at Penn Medicine; Other
Eligibility: 18 Years to 120 Years · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Infected Seroma After Surgical Procedure
Interventions: Penrose drain placement; Device
Lead sponsor: Michigan State University; Other
Eligibility: 45 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Lansing, Michigan

Conditions: Breast Cancer
Interventions: accelerated partial breast irradiation - 3D-conformal planning, accelerated partial breast irradiation - IMRT planning; Radiation
Lead sponsor: Rocky Mountain Cancer Centers; Other
Eligibility: 40 Years and older
Enrollment: 660 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2028
U.S. locations: 5
States / cities: Aurora, Colorado • Boulder, Colorado • Lakewood, Colorado + 2 more

Conditions: Breast Cancer
Interventions: 5 Fraction Stereotactic Body Radiation Therapy; Radiation
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2028
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Ductal Carcinoma in Situ, Invasive Ductal Carcinoma of Female Breast
Interventions: stereotactic body radiation therapy; Radiation
Lead sponsor: RPCR, Inc.; Other
Eligibility: 50 Years to 100 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2027
U.S. locations: 2
States / cities: Stuart, Florida • Tampa, Florida

Conditions: Breast Cancer
Interventions: 4D Conformal Image-Guided Partial Breast RT; Radiation
Lead sponsor: Yale University; Other
Eligibility: 50 Years and older · Female only
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Invasive Breast Cancer Early Stages, Ductal Carcinoma In Situ, DCIS
Interventions: VENUS SHELL™ immobilization device; Device
Lead sponsor: HeroSupport SA; Industry
Eligibility: 40 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Breast Cancer, Carcinoma, Lumpectomy, Ductal Carcinoma in Situ
Interventions: Electronic Brachytherapy, Intracavitary accelerated partial breast irradiation; Radiation
Lead sponsor: Xoft, Inc.; Industry
Eligibility: 50 Years and older · Female only
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 8
States / cities: Tuscaloosa, Alabama • Montebello, California • Orange Park, Florida + 5 more

Conditions: Breast Cancer, DCIS, LCIS
Interventions: MRIdian Radiation Treatment Unit; Radiation
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 40 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2031
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Breast Cancer
Interventions: Accelerated Partial Breast Irradiation, AlignRT; Radiation · Device
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 40 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Breast Cancer
Interventions: Breast Brachytherapy with Mammosite RTS, Intensity Modulated Radiotherapy; Radiation
Lead sponsor: Rocky Mountain Cancer Centers; Other
Eligibility: 40 Years and older
Enrollment: 291 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2024
U.S. locations: 6
States / cities: Aurora, Colorado • Boulder, Colorado • Denver, Colorado + 3 more

Conditions: Breast Cancer
Interventions: 3-dimensional conformal accelerated partial breast irradiation, brachytherapy, whole breast irradiation, MammoSite or other single-entry intracavitary device; Radiation
Lead sponsor: NSABP Foundation Inc; Network
Eligibility: 18 Years and older · Female only
Enrollment: 4,216 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2018
U.S. locations: 374
States / cities: Birmingham, Alabama • Peoria, Arizona • Phoenix, Arizona + 295 more

Conditions: Breast Cancer
Interventions: Contura catheter; Device
Lead sponsor: Cancer Center of Irvine; Other
Eligibility: 18 Years and older · Female only
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Irvine, California

Conditions: Breast Cancer
Interventions: CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI); Radiation
Lead sponsor: Georgetown University; Other
Eligibility: 50 Years to 99 Years · Female only
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Breast Cancer, Quality of Life
Interventions: Accelerated Partial Breast Irradiation (APBI), tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene; Radiation · Drug
Lead sponsor: UNC Lineberger Comprehensive Cancer Center; Other
Eligibility: 65 Years and older · Female only
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2032
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Breast Cancer, DCIS, Invasive Ductal Carcinoma
Interventions: CK Stereotactic Accelerated Partial Breast Irradiation; Radiation
Lead sponsor: Georgetown University; Other
Eligibility: 50 Years to 99 Years · Female only
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Breast Cancer
Interventions: Accelerated partial breast irradiation; Device
Lead sponsor: Cancer Center of Irvine; Other
Eligibility: 50 Years and older · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Irvine, California

Conditions: Invasive Ductal Breast Carcinoma, Invasive Ductal Carcinoma, Breast, DCIS, DCIS Grade 1, DCIS Grade 2, Breast Cancer
Interventions: Accelerated Partial Breast Irradiation; Radiation
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 45 Years and older · Female only
Enrollment: 280 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2027
U.S. locations: 9
States / cities: Norwalk, Connecticut • Miami, Florida • Basking Ridge, New Jersey + 6 more

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Registry for Accelerated Partial Breast Irradiation With (SBRT) or (IMRT)

A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca

Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Preoperative Accelerated Partial Breast Irradiation (APBI) for Women With Stage I and Select IIA Breast Cancer

Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer

Evaluation of Accelerated Partial Breast Brachytherapy

Partial Breast Radiation Therapy in Treating Women Undergoing Breast Conservation Therapy for Early-Stage Breast Cancer

Drain Placement for Seroma Prevention After Mammosite/SAVI Catheter Removal

Intensity Modulated Radiotherapy (IMRT) vs. 3D-conformal Accelerated Partial Breast Irradiation (APBI) for Early Stage Breast Cancer After Lumpectomy

RAD 1802: Pilot Trial of Five Fraction Stereotactic Body Radiotherapy for Early Stage Breast Cancer Patients Eligible for Post-Operative Accelerated Partial Breast Irradiation (APBI)

Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT)

4D Image-Guided Partial Breast Radiation in Stage 0 and l Breast Cancer

Personalized Prone Immobilization for Accelerated Partial Breast Radiotherapy

Electronic Xoft Intersociety Brachytherapy Trial: Electronic Brachytherapy (EBT) For Treatment of Early Stage Breast Cancer

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

Preoperative Accelerated Partial Breast Irradiation for Triple Negative Breast Cancer Using Proton Beam Scanning

Accelerated Partial Breast Radiotherapy With Either Mammosite or Intensity Modulated Radiotherapy

Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer

Use of the Contura™ Catheter in Intermediate-Risk, Pathological Stage 0, I, or II (Up to 3.0 cm) Breast Cancer Patients

A Multi-Institutional Registry for CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI)

Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)

Use of the Contura™ Catheter to Deliver Accelerated Partial Breast Irradiation to "Low-risk" Breast Cancer Patients

Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer