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ClinicalTrials.gov public records Last synced Oct 21, 2026, 10:56 AM EDT

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Showing 145–168 of 298 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Acceptance commitment therapy Clear all
Completed Not applicable Interventional Accepts healthy volunteers

The REACH Study: A Novel Values-Based Intervention to Increase Endocrine Therapy Adherence Among Breast Cancer Survivors

NCT03980093
View directory record Official record
Conditions
Breast Cancer
Interventions
Education, Values
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenwood Village, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Open Trial to Improve Retention in Care for Persons With HIV Who Use Substances

NCT05101044
View directory record Official record
Conditions
Substance Use Disorders, Hiv
Interventions
Acceptance-based Behavioral Therapy (ABBT) Intervention
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 21, 2026, 10:56 AM EDT
Recruiting Not applicable Interventional

Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT

NCT06819904
View directory record Official record
Conditions
Concussion, Mild, Mild Traumatic Brain Injury (mTBI), Psychological Health
Interventions
Acceptance and Commitment Therapy Integrated Rehabilitation (ACT), Usual Care Rehabilitation
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 49 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Not listed No phase listed Observational

Biometrics and Self-reported Health Changes in Adults Receiving Behavioral Treatments for Chronic Pain

NCT05812703
View directory record Official record
Conditions
Chronic Pain, Sedentary Time
Interventions
Cognitive Behavioral Therapy, Acceptance and Commitment Therapy (ACT), Moderate to high Intensity Group Exercise
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Facilitating Treatment Entry and Family Planning in Substance-using Neonatal Intensive Care Unit (NICU) Mothers

NCT03165565
View directory record Official record
Conditions
Substance Use Disorders
Interventions
Motivational Interviewing (MI) and Acceptance and Commitment Therapy (ACT), Conventional Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindset Intervention for Nicotine Dependence

NCT03174730
View directory record Official record
Conditions
Psychology, Social, Smoking Cessation, Smoking (Tobacco) Addiction
Interventions
Growth Mindset, SmartQuit
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
398 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Impact of Acceptance and Commitment Therapy on Early Stage Breast Cancer

NCT01164930
View directory record Official record
Conditions
Breast Neoplasms, Survivorship, Stress
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
San Jose State University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2021 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Pilot RCT

NCT04269772
View directory record Official record
Conditions
Bipolar Disorder
Interventions
CARE, Treatment As Usual
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Cranston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Trial of Web-Delivered Acceptance Therapy for Smoking Cessation (WebQuit)

NCT01812278
View directory record Official record
Conditions
Smoking
Interventions
ACT, CBT
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 99 Years
Enrollment
2,637 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 21, 2026, 10:56 AM EDT
Enrolling by invitation Not applicable Interventional

Testing the Efficacy of ACT for Life

NCT04829682
View directory record Official record
Conditions
Suicide
Interventions
ACT for Life, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Battle Creek, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Storytelling Video Intervention for Depressed Primary Care Patients - Pilot Trial

NCT02311725
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
aTAU + sTVi, aTAU + Attention Control Videos
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

Possible Therapy by Phone for Caregivers

NCT04634396
View directory record Official record
Conditions
Anxiety, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
ACT Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

"ACT" for Parents of Children With Autism Spectrum Disorder

NCT02255786
View directory record Official record
Conditions
Stress
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Lexington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Examining the Efficacy of Acceptance and Commitment Therapy (ACT) Microinterventions for Distressed First-Generation College Students

NCT04081662
View directory record Official record
Conditions
Psychological Distress, Self-Assessment, Mood Change
Interventions
compACT Intervention
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 19 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 6, 2021 · Synced Oct 21, 2026, 10:56 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Family-Focused Study to Support Medication for Opioid Use Disorder

NCT07451197
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
Interventions
FamilyCHESS, Standard of Care
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
2
States / cities
Chicago, Illinois • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

Telephone Support for Metastatic Breast Cancer Patients

NCT03998618
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Acceptance and Commitment Therapy, Education/Support
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Treating Anxiety Symptoms With ACT Improve Vascular Inflammation and Function?

NCT02915874
View directory record Official record
Conditions
Anxiety
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
25 Years to 65 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

FlexED: A Digital, Gamified Early Intervention for Eating Disorders

NCT05609409
View directory record Official record
Conditions
Eating Disorders, Body Image
Interventions
FlexED
Behavioral
Lead sponsor
Duke University
Other
Eligibility
15 Years to 25 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Active, not recruiting Not applicable Interventional

Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment

NCT05039554
View directory record Official record
Conditions
Opioid-use Disorder, Chronic Pain
Interventions
Acceptance and commitment therapy, Valera Smartphone Application, Treatment as Usual
Behavioral · Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptive Mobile Interventions to Reduce Cancer Risk Behaviors

NCT07585357
View directory record Official record
Conditions
Smoking Cessation
Interventions
Smartphone-based intervention messages
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 40 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional

The Duluth Model and ACTV for Domestic Violence

NCT03609801
View directory record Official record
Conditions
Domestic Violence
Interventions
ACTV, The Duluth Model
Behavioral
Lead sponsor
Iowa State University
Other
Eligibility
18 Years and older · Male only
Enrollment
799 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Des Moines, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 30, 2024 · Synced Oct 21, 2026, 10:56 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Virtual ACT for Adolescent Stress

NCT04978610
View directory record Official record
Conditions
Chronic Illness
Interventions
Virtual Acceptance Commitment Therapy
Behavioral
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
14 Years to 21 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 21, 2026, 10:56 AM EDT
Completed Not applicable Interventional Results available

One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change

NCT04143243
View directory record Official record
Conditions
Traumatic Brain Injury, Chronic Pain, Post Traumatic Stress Disorder, Depression, Anxiety
Interventions
ACT on Life, Education, Resources, and Support
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 21, 2026, 10:56 AM EDT
Not yet recruiting Not applicable Interventional

Feasibility, Acceptability, and Safety Trial of Brief, Breath Control-Focused Acceptance and Commitment Therapy in Adults With Chronic Cough

NCT07566117
View directory record Official record
Conditions
Chronic Cough
Interventions
Acceptance and Commitment Therapy (ACT)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 10:56 AM EDT