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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Acceptance- and commitment-based behavioral therapy Clear all
Recruiting Not applicable Interventional

Engage Psychosocial Intervention for Cancer Symptoms

NCT06555588
View directory record Official record
Conditions
Advanced Breast Cancer, Advanced Prostate Cancer, Advanced Lung Cancer, Advanced Colorectal Carcinoma, Advanced Colorectal Adenocarcinoma
Interventions
ENGAGE, Supportive Care
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Repetitive Transcranial Magnetic Stimulation and Acceptance and Commitment Therapy

NCT05427201
View directory record Official record
Conditions
Chronic Pain, Depression
Interventions
Repetitive Transcranial Magnetic Stimulation, Acceptance and Commitment Therapy
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Project CARE: An Integrated Treatment Adherence Program for Bipolar Disorder at the Time of Prison Release - Open Trial

NCT03825640
View directory record Official record
Conditions
Bipolar Disorder
Interventions
CARE
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
Cranston, Rhode Island • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Brief Acceptance-Based Retention Intervention for Newly Diagnosed HIV Patients

NCT04201288
View directory record Official record
Conditions
HIV/AIDS
Interventions
Acceptance-Based Behavior Therapy (ABBT), Enhanced-Treatment-as-Usual (ETAU)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 20, 2026, 2:09 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Promoting the Well Being of Caregivers Via Telehealth

NCT05999448
View directory record Official record
Conditions
Caregivers, Parents
Interventions
Acceptance and Commitment Therapy (ACT), Culturally Informed Cognitive Behavioral Therapy (CICBT), Individual, Culturally Informed Cognitive Behavioral Therapy (CICBT), Group, Dialectical Behavioral Therapy (DBT), Durand Sleep Intervention, RUBI Intervention, Naturalistic Communication Intervention (NCI), Self-Guided Resources, Participation Enhancement Intervention (PEI)
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 70 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

iOmit: Reducing Intentional Insulin Misuse in Type 1 Diabetes

NCT02980627
View directory record Official record
Conditions
Type 1 Diabetes Mellitus, Eating Disorders
Interventions
Therapy with Mobile App Enhancement
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

ACT for High-risk Pregnancy

NCT04193514
View directory record Official record
Conditions
Acceptance and Commitment Therapy
Interventions
Acceptance and Commitment Therapy
Other
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Phase 2 Interventional Results available

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

NCT02896712
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Acceptance and Commitment Therapy (ACT), Drug Counseling (DC), Contingency Management (CM), Placebo, Modafinil
Behavioral · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 60 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2023 · Synced Sep 20, 2026, 2:09 PM EDT
Enrolling by invitation Not applicable Interventional

Testing the Efficacy of ACT for Life

NCT04829682
View directory record Official record
Conditions
Suicide
Interventions
ACT for Life, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Battle Creek, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Acceptance and Commitment Therapy for Religious OCD

NCT06647589
View directory record Official record
Conditions
Obsessive-Compulsive Disorder (OCD)
Interventions
Acceptance and Commitment Therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use

NCT06366633
View directory record Official record
Conditions
Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
Interventions
Web-TIRELESS
Behavioral
Lead sponsor
Jafar Bakhshaie
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Increasing Access to Evidence-based Treatment for Chronic Pain and Opioid Use Disorder: Adapting Acceptance and Commitment Therapy for Opioid Treatment Programs

NCT06581276
View directory record Official record
Conditions
Opioid Use, Opioid Use Disorder, Chronic Pain
Interventions
Acceptance and Commitment Therapy (ACT)
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessment of the Predictors and Moderators of Health Behavior Change

NCT03139656
View directory record Official record
Conditions
Health Behaviors
Interventions
Values Clarification, Planning, Combined
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Sep 20, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

The Trans-Led Care Study

NCT06880705
View directory record Official record
Conditions
Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol), Human Immunodeficiency Virus (HIV)
Interventions
The TLC Program
Behavioral
Lead sponsor
Illinois Institute of Technology
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Distress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid Dependence

NCT02602795
View directory record Official record
Conditions
Opiate Dependence, Sexually Transmitted Diseases, HIV
Interventions
Acceptance and Commitment Therapy, Information Motivation Behavioral Model
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 28, 2018 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Acceptance-based Group Intervention for Binge Eating

NCT01757847
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Acceptance and Commitment Therapy (ACT), Brief MOVE-II control group intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2016 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

A Study of a Values-Based Intervention to Promote Weight Loss

NCT03991676
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Values-Based Behavioral Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2019 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Sense2Stop:Mobile Sensor Data to Knowledge

NCT03184389
View directory record Official record
Conditions
Stress, Smoking Cessation, Overeating
Interventions
Prompt to use smartphone apps for stress management
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Acceptability of a Stigma Text Message Intervention for People Who Use Drugs

NCT06281548
View directory record Official record
Conditions
Stigma, Social, Substance Use
Interventions
RESTART
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Portsmouth, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Telephone Acceptance and Commitment Therapy Intervention for Caregivers of Adults With Dementia

NCT04338750
View directory record Official record
Conditions
Anxiety, Anxiety Generalized, Anxiety Disorders and Symptoms, Caregiver Burnout
Interventions
Telephone Acceptance and Commitment Therapy Intervention for Caregivers, minimally-Enhanced Usual Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Sep 20, 2026, 2:09 PM EDT
Terminated Not applicable Interventional

Evaluating the Feasibility of a Stepped-care Approach to Treating Adolescents With Binge and Loss of Control Eating

NCT03404713
View directory record Official record
Conditions
Overweight and Obesity, Pediatric Obesity, Eating, Binge
Interventions
Pathways to Health, Be4U
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
13 Years to 18 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional

Acceptance and Commitment Therapy for Chronic Pain in Integrated Primary Care

NCT04978961
View directory record Official record
Conditions
Chronic Pain
Interventions
Focused Acceptance & Commitment Therapy (FACT), Enhanced Treatment as Usual (ETAU)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 99 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2021 · Synced Sep 20, 2026, 2:09 PM EDT
Recruiting Not applicable Interventional

Training in Evidence-based Treatments in Psycho-Oncology

NCT05674357
View directory record Official record
Conditions
Distress, Emotional, Depression, Anxiety, Fatigue, Pain, Insomnia
Interventions
Individualized Evidence-Based Therapy in Cancer (Patients and Caregivers), Training in Individualized Evidence-Based Therapy in Cancer (Therapists)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 20, 2026, 2:09 PM EDT
Completed Not applicable Interventional Results available

Acceptance and Commitment Therapy for Chronic Pain in Cancer Survivors

NCT03661840
View directory record Official record
Conditions
Chronic Pain
Interventions
Acceptance and Commitment Therapy, Treatment as Usual
Behavioral · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 20, 2026, 2:09 PM EDT