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ClinicalTrials.gov public records Last synced Nov 4, 2026, 2:56 AM EST

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Showing 1–24 of 948 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Acetaminophen/ Paracetamol Clear all

Conditions: Opioid Use
Interventions: Modification of opioid prescription method; Other
Lead sponsor: John Yanik; Other
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Sarcopenia, Osteoporosis, Aging
Interventions: Resistance training; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years and older · Male only
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2011
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Osteoarthritis
Interventions: Myalgesin™ (celery seed extract, Boswellia serrata extract, Phellodendron extract); Dietary Supplement
Lead sponsor: ProThera, Inc.; Industry
Eligibility: 50 Years and older
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Albany, New York

Conditions: Acute Low Back Pain
Interventions: Combination drug (Acetaminophen + Tramadol), Placebo; Drug
Lead sponsor: Labopharm Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 277 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 18
States / cities: Montgomery, Alabama • Centennial, Colorado • Hialeah, Florida + 14 more

Conditions: Immune Thrombocytopenia
Interventions: Acetaminophen and Diphenhydramine Only Product; Drug
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 1 Month to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Breast Cancer, Postoperative Pain
Interventions: Liposomal bupivacaine, Bupivacaine with epinephrine, Morphine sulfate, Hydrocodone/acetaminophen, Diazepam; Drug
Lead sponsor: Loma Linda University; Other
Eligibility: 18 Years to 99 Years · Female only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Healthy, Obese, Overweight
Interventions: Orforglipron, Simvastatin, Digoxin, Rosuvastatin, Acetaminophen, Midazolam, Sodium Bicarbonate; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 2
States / cities: Daytona Beach, Florida • Dallas, Texas

Conditions: Opioid-Related Disorders, Pain, Acute, Pain, Postoperative
Interventions: GRT7014 - Abuse Deterrend Tablet, Norco 5Mg-325Mg Tablet; Drug
Lead sponsor: Grünenthal GmbH; Industry
Eligibility: 18 Years to 55 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Lenexa, Kansas

Conditions: Pompe Disease
Interventions: Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase, Rapamycin, saline, Rituxan, Diphenhydramine, Acetaminophen, Lidocaine, LMX 4 Topical Cream; Genetic · Drug · Other
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 50 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Pharyngitis
Interventions: Acetylsalicylic Acid (Aspirin, BAY1019036) + placebo, Acetaminophen + placebo, Placebo; Drug
Lead sponsor: Bayer; Industry
Eligibility: 18 Years and older
Enrollment: 177 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Storrs, Connecticut

Conditions: Orthopaedic Trauma, Chronic Opioid Use
Interventions: Ketorolac Injection, Standard of Care (SOC) Multimodal Analgesia; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 70 Years
Enrollment: 458 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Boston, Massachusetts • Nashville, Tennessee

Conditions: Systemic Sclerosis-Associated PAH
Interventions: Rituximab, Placebo, CMRI, prednisone, methylprednisolone, diphenhydramine, acetaminophen; Biological · Other · Diagnostic Test + 1 more
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 75 Years
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 17
States / cities: Stanford, California • Aurora, Colorado • Iowa City, Iowa + 13 more

Conditions: Postoperative Pain, Hysterectomy
Interventions: IV Acetaminophen, IV Placebo 100 mL solution; Drug
Lead sponsor: Mallinckrodt; Industry
Eligibility: 18 Years to 75 Years · Female only
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2007
U.S. locations: 27
States / cities: Birmingham, Alabama • Sheffield, Alabama • Phoenix, Arizona + 21 more

Conditions: Toothache
Interventions: Acetaminophen/Oxycodone (Oral analgesic), Bupivicaine (Injectable local anesthetic); Drug
Lead sponsor: Stony Brook University; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Stony Brook, New York

Conditions: Obesity, Childhood
Interventions: Tylenol; Drug
Lead sponsor: Children's National Research Institute; Other
Eligibility: 10 Years to 18 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Interventions: D-Cycloserine, Placebo (for D-cycloserine); Drug
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Adolescent Idiopathic Scoliosis (AIS)
Interventions: Opioid-Free/Opioid-Avoidant, Opioid-Containing; Drug
Lead sponsor: OrthoCarolina Research Institute, Inc.; Other
Eligibility: 10 Years to 20 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Charlotte, North Carolina

Conditions: Pain
Interventions: Acetaminophen, Placebo Control; Drug
Lead sponsor: McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.; Industry
Eligibility: 16 Years to 50 Years
Enrollment: 540 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Aneurysmal Subarachnoid Hemorrhage, Cerebral Vasospasm
Interventions: Placebos for acetaminophen and N-acetylcysteine, APAP 1 gm every 6 hours and N-acetylcysteine placebo, NAC IV infusion at 0.5 gm hourly and APAP placebo, APAP 1 gm q6 hours, plus NAC IV infusion at 0.5 gm hourly, APAP 1.5 gm q6 hours, plus NAC IV infusion at 0.5 gm hourly; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 20 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Apnea of Prematurity, Retinopathy of Prematurity, Pain
Interventions: sucrose solution; Dietary Supplement
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 5 Weeks and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2005
U.S. locations: 1
States / cities: New York, New York

Conditions: Metastatic Castration-resistant Prostate Cancer, Prostate Cancer, Prostate Neoplasm, Advanced Solid Tumor, Solid Tumor, Non-metastatic Castration-resistant Prostate Cancer
Interventions: M7824, N-803, MVA-BN-Brachyury, FPV-Brachyury, Epacadostat, Acetaminophen, Ibuprofen, Naproxen, Benadryl, EKG, Bone scan, CT chest, abdomen and pelvis, MRI; Biological · Drug · Other + 1 more
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years to 120 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Nail Diseases, Nail Abnormality
Interventions: Hydrocodone 5Mg/Acetaminophen 325Mg Tab, Acetaminophen 1000mg, Ibuprofen 400 mg; Drug
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 95 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Dental Pain
Interventions: Acetaminophen ER, Placebo; Drug
Lead sponsor: McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.; Industry
Eligibility: 17 Years to 45 Years
Enrollment: 403 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Concussion, Mild, Traumatic Brain Injury, Mild
Interventions: Magnesium, Placebo; Dietary Supplement · Drug
Lead sponsor: Corewell Health South; Other
Eligibility: 12 Years to 18 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Saint Joseph, Michigan

Search by objective public record fields.

Does Altering Narcotic Prescription Methods Affect Opioid Distribution Following Select Upper Extremity Surgeries?

Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training

Efficacy of Myalgesin™ to Support Joint Function in Patients With Knee Osteoarthritis

A Two-Arm Study Comparing the Analgesic Efficacy and Safety of Acetaminophen and Tramadol Combination BID Versus Placebo for the Treatment of Acute Low Back Pain

Post IVIG Medication in Children With Immune Thrombocytopenia

Liposomal Bupivacaine in Implant Based Breast Reconstruction

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults

Re-administration of Intramuscular AAV9 in Patients With Late-Onset Pompe Disease

Evaluate the Time of Pain Relief of Fast Acting Aspirin Versus Acetaminophen in Subjects Diagnosed With Sore Throat Pain

Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients

Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)

Efficacy and Safety of Intravenous Acetaminophen Over 48 Hrs for the Treatment of Post-op Pain After Gynecologic Surgery

Percocet vs. Bupivicaine for Toothaches in the ED

Acetaminophen Dosing in Obese Adolescents

Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain

Prospective Opioid-Free AIS Fusion

To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery

Acetaminophen in aSAH to Inhibit Lipid Peroxidation and Cerebral Vasospasm

Use of Sucrose to Relieve Pain During Eye Exams in Infants

Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)

Hydrocodone Compared to Acetaminophen and Ibuprofen for Post-nail Procedure Analgesia

Study of Long-Acting Acetaminophen in Postoperative Dental Pain

Mag Con: Efficacy of Oral Mag. in Acute Concussion in Adolescents