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ClinicalTrials.gov public records Last synced Nov 13, 2026, 1:13 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 193–216 of 235 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Active Lighting Intervention Clear all

Conditions: Non-small Cell Lung Cancer Metastatic, Targetable Oncogenes (EGFR, ALK, ROS1)
Interventions: SBRT with protons or photons; Radiation
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Pediatric Obesity, Pediatric Asthma
Interventions: Pro2 - 60% of participant's MIP, Pro2 - 15% of participant's MIP; Device
Lead sponsor: Duke University; Other
Eligibility: 8 Years to 17 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Cognition Improvement, Emotion Regulation
Interventions: Active transcranial photobiomodulation, Active MCT dietary supplementation, Sham photobiomodulation, Sham dietary supplementation; Device · Dietary Supplement
Lead sponsor: Francisco Gonzalez-Lima, PhD; Other
Eligibility: 18 Years to 85 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Epilepsy
Interventions: Photobiomodulation; Other
Lead sponsor: Cynthia Kerson; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: North Miami, Florida • Cincinnati, Ohio • Warren, Ohio + 1 more

Conditions: Obesity
Interventions: Fitbit Charge HR plus weekly phone calls to review physical activity data; Other
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 7 Years to 18 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
Interventions: Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 830 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 47
States / cities: Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 31 more

Conditions: Parkinson Disease
Interventions: Active NIR-PBM (MedX 1116, MCT502), Sham NIR-PBM (MedX 1116, MCT502); Device
Lead sponsor: University of Florida; Other
Eligibility: 62 Years to 89 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Obesity
Interventions: FB Professional LED Red light therapy, Effects of Red Light LED Therapy on Body Contouring; Device
Lead sponsor: Manamed Inc.; Industry
Eligibility: 18 Years to 77 Years
Enrollment: 66 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: New Port Richey, Florida

Conditions: Metabolic Syndrome, Obesity
Interventions: Exercise Intervention; Behavioral
Lead sponsor: Plymouth State University; Other
Eligibility: 18 Years to 39 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2024
U.S. locations: 2
States / cities: Plymouth, New Hampshire

Conditions: Prediabetes
Interventions: Hourly 3-Minute Light Walking Breaks, Hourly Stair-Climbing Exercise Snacks; Behavioral
Lead sponsor: St. Louis University; Other
Eligibility: 18 Years to 69 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Chronic Kidney Diseases, Obesity
Interventions: SLIMM, Standard Resistance Training, Guided Resistance Training, Placebo, Semaglutide; Behavioral · Drug
Lead sponsor: Srinvasan Beddhu; Other
Eligibility: 20 Years and older
Enrollment: 156 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 2
States / cities: Stanford, California • Salt Lake City, Utah

Conditions: Plantar Fascitis
Interventions: Photobiomodulation Therapy (PBMT), Sham-Photobiomodualtion Therapy (Sham-PBMT); Device
Lead sponsor: The Geneva Foundation; Other
Eligibility: 18 Years to 64 Years
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Tacoma, Washington

Conditions: Parkinson Disease, Sleep Disturbance
Interventions: Tailored Lighting Intervention (LIT), Actigraph; Device
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: New York, New York

Conditions: Acute Respiratory Distress Syndrome
Interventions: R2 Bundle; Other
Lead sponsor: University of Pennsylvania; Other
Eligibility: 6 Months to 17 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 2
States / cities: Baltimore, Maryland • Philadelphia, Pennsylvania

Conditions: Long COVID, Long COVID-19, Sleep Disturbance
Interventions: Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo; Drug · Device
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 469 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Diabetic Neuropathy, Painful
Interventions: Prolonged continuous theta burst stimulation (pcTBS); Procedure
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Concussion, Intermediate
Interventions: magnesium and riboflavin supplement; Drug
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 40 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Traumatic Brain Injury
Interventions: STEP, Control; Behavioral
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 14 Years to 22 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Sedentary Time, Frailty
Interventions: Continuous sedentary reduction intervention, Bouted sedentary reduction intervention; Behavioral
Lead sponsor: Johns Hopkins Bloomberg School of Public Health; Other
Eligibility: 65 Years and older
Enrollment: 61 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Surgery
Interventions: Functioning Aerus air filtration/sterilization, Deactivated Aerus air filtration/sterilization; Device
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years and older
Enrollment: 66,273 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: HIV Infections, Sexually Transmitted Diseases
Interventions: Abstinence-only HIV/STD risk-reduction intervention, Safer-sex-only HIV/STD risk-reduction intervention, Long comprehensive HIV/STD risk-reduction intervention, Short comprehensive HIV/STD risk-reduction intervention, Health promotion control intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: Not listed
Enrollment: 662 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2004
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sedentary Behavior, Exercise, Middle Age, Adult
Interventions: Decrease Sedentary Time + Increase MVPA group, Increase MVPA group; Behavioral
Lead sponsor: University of Illinois at Urbana-Champaign; Other
Eligibility: 45 Years to 65 Years
Enrollment: 88 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Urbana, Illinois

Conditions: Bipolar Disorder
Interventions: Metformin, healthy lifestyle intervention (LIFE); Drug · Behavioral
Lead sponsor: Melissa Delbello; Other
Eligibility: 8 Years to 19 Years
Enrollment: 1,565 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 29
States / cities: Covington, Kentucky • Neptune City, New Jersey • Amityville, New York + 13 more

Conditions: Refractory Myelodysplastic Syndrome
Interventions: Actinium Ac 225 Lintuzumab, Bone Marrow Aspiration, Buccal Swab, Computed Tomography, Single Photon Emission Computed Tomography; Radiation · Procedure
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: 18 Years and older
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

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A Trial of Integrating SBRT With Targeted Therapy in Stage IV Oncogene-driven NSCLC

Inspiratory Pulmonary Rehabilitation for Children With Obesity and Asthma

Increasing Mitochondrial Respiration as a Novel Mechanism for Cognitive Augmentation

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

Impact of Fitbit Plus Weight Management Program on Physical Activity and Metabolic Disease in Obese Adolescents

RECOVER-SLEEP: Platform Protocol

Revitalize Cognition: Near Infrared Stimulation in Parkinson Patients

Effects of Red Light LED Therapy on Body Contouring

Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control

Effects of Hourly Stair-Climbing Exercise Snacks on Metabolic and Vascular Health in Adults With Prediabetes

Sit Less, Interact and Move More (SLIMM) 2 Study

Low-Level Laser Therapy for Plantar Fasciitis

Lighting Intervention to Improve Sleep

Restore Resilience in Critically Ill Children

RECOVER-SLEEP: Platform Protocol, Appendix_B (CPSD)

Theta Burst Brain Stimulation in Diabetic Neuropathy Patients With Neuropathic Pain: Investigating Neural Mechanisms

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Subsymptom Threshold Exercise Protocol Following Mild TBI

The Sedentary to Active Rising to Thrive (START) Trial

Operating Room Air Filtration/Sterilization

Efficacy of an Abstinence-Only HIV Risk-Reduction Intervention for Young African-American Adolescents

One Step at a Time: An Intervention to Reduce Sedentary Behavior Among Working Adults

Metformin for Overweight & OBese ChILdren and Adolescents With BDS Treated With SGAs

Testing an Anti-cancer Radio-Active Immunotherapy Called Lintuzumab Ac225 in Patients With High-Risk Myelodysplastic Syndrome That Has Not Responded to Other Treatment