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ClinicalTrials.gov public records Last synced Oct 18, 2026, 12:34 PM EDT

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Showing 1–24 of 42 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Active Neurofeedback Training Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Training Upper Limbs of Neurodiverse Children by Connecting Brain Activities to a Virtual Reality Based Game

NCT06818877
View directory record Official record
Conditions
Healthy Children, CP (Cerebral Palsy), CP, Cerebral Palsy
Interventions
Brain-Computer Interface (BCI)-HABIT-VR, Hand and Bimanual Intensive Therapy Virtual Reality (HABIT-VR)
Device
Lead sponsor
University of Nebraska
Other
Eligibility
6 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

Neurofeedback From the Supplementary Motor Area for Tourette Syndrome

NCT05558566
View directory record Official record
Conditions
Tourette Syndrome in Adolescence
Interventions
Neurofeedback from the SMA, Neurofeedback from control region
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Results available

Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD

NCT02251743
View directory record Official record
Conditions
Attention-Deficit/Hyperactivity Disorder
Interventions
Neurofeedback treatment
Device
Lead sponsor
Ohio State University
Other
Eligibility
7 Years to 10 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
2
States / cities
Asheville, North Carolina • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 29, 2020 · Synced Oct 18, 2026, 12:34 PM EDT
Terminated Not applicable Interventional Results available

Circuitry Assessment and Reinforcement Training Effects on Recovery

NCT04290988
View directory record Official record
Conditions
Aphasia, Primary Progressive Aphasia, Stroke
Interventions
EEG Neurofeedback, Sham Feedback
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans

NCT06217575
View directory record Official record
Conditions
Traumatic Brain Injury, Mild Traumatic Brain Injury, Aging, Cognitive Decline
Interventions
Alpha neurofeedback training, Visual Attention Training
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
50 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial

NCT03702712
View directory record Official record
Conditions
Breast Cancer
Interventions
Aerobic Exercise and Relaxation, Aerobic Exercise Only, Relaxation Only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Using EEG Operant Conditioning to Improve Trait Self-Control and Promote Healthy Behavior

NCT01801254
View directory record Official record
Conditions
Obesity, Type II Diabetes, Cardiovascular Disease, Health Behavior
Interventions
STRIDES, Sham Control
Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Oct 18, 2026, 12:34 PM EDT
Not yet recruiting Not applicable Interventional

Mindfulness-based Neurofeedback to Reduce Negative Thinking in CHARMS Adolescents

NCT06901232
View directory record Official record
Conditions
Repetitive Negative Thinking, Serious Mental Illness Symptoms
Interventions
Mindfulness Training, Active mindfulness-based neurofeedback (Active mbNF), Sham mindfulness-based neurofeedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 21 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

Neurofeedback to Treat Depression - 2

NCT07159061
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Active Closed Loop Real Time fMRI Neurofeedback, Sham Closed Loop Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Emotion Study -- A Neurofeedback Approach

NCT02194907
View directory record Official record
Conditions
Aging, Emotion
Interventions
Brain activity training - anterior insula, Brain activity training - medial prefrontal cortex
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

Targeting Large-scale Networks in Depression With Real-time Functional Magnetic Resonance Imaging (fMRI) Neurofeedback

NCT06050070
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
FMRI with sham controlled feedback, FMRI with real time feedback
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Rate Variability Biofeedback: It's Role in Asthma Therapeutics

NCT02766374
View directory record Official record
Conditions
Asthma
Interventions
Heart rate variability biofeedback, Placebo
Behavioral
Lead sponsor
Fred Wamboldt, MD
Other
Eligibility
18 Years to 75 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2018
U.S. locations
2
States / cities
Denver, Colorado • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Phase 2 Interventional

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

NCT07020312
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Hip Arthroscopy
Interventions
Visualization training with neurofeedback, Standard post-surgical rehabilitation therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Teen Brain Training (TBT)

NCT06183580
View directory record Official record
Conditions
Suicide, Attempted, Suicide, Ideation, Depression
Interventions
neurofeedback training involving dACC, neurofeedback training involving amygdala
Other
Lead sponsor
University of Minnesota
Other
Eligibility
11 Years to 18 Years
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

Neurofeedback During Eating for Bulimia Nervosa

NCT05614024
View directory record Official record
Conditions
Bulimia Nervosa
Interventions
Real fNIRS Neurofeedback, Sham-Control fNIRS Neurofeedback
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmenting Mindfulness Training Through Experience-driven Neurofeedback

NCT02413177
View directory record Official record
Conditions
Stress
Interventions
EEG-no RTNF, EEG-RTNF
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 30, 2018 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

Neurofeedback to Treat Depression

NCT05169346
View directory record Official record
Conditions
MDD
Interventions
Active Closed Loop Real Time fMRI Neurofeedback, Sham Closed Loop Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

HRV Biofeedback in Fibromyalgia

NCT00222274
View directory record Official record
Conditions
Fibromyalgia Syndrome
Interventions
RSA Biofeedback, EEG Biofeedback Condition
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

Mindfulness Surgical Pain Outcomes

NCT05838443
View directory record Official record
Conditions
Post Surgical Pain, Surgery
Interventions
Self-directed mindfulness utilizing a multi-sensor EEG-supported device with neurofeedback-assisted and technology-supported meditation, Provider-directed mindfulness, Conventional Care
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

Neurofeedback Training for High Risk Psychosis

NCT03447548
View directory record Official record
Conditions
Prodromal Schizophrenia
Interventions
Neurofeedback processing speed training, Active control
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
12 Years to 25 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking

NCT07055217
View directory record Official record
Conditions
Repetitive Negative Thinking, Neurofeedback
Interventions
Mindfulness Training, Mindfulness-based Neurofeedback (Real mbNF), Sham mindfulness-based neurofeedback (Sham mbNF)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
13 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Toward a Generalizable Closed-loop Neurofeedback-based BCI for Attention Training

NCT05908253
View directory record Official record
Conditions
Neurofeedback
Interventions
sham neurofeedback, nonadaptive neurofeedback, adaptive neurofeedback
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Kingston, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 2, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

A Study of a Novel EEG Neurofeedback System for PTSD Treatment

NCT06770998
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
EEG-neurofeedback training, Sham training
Device
Lead sponsor
Foundation for Atlanta Veterans Education and Research, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Decatur, Georgia • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Not yet recruiting Not applicable Interventional

Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa

NCT07581158
View directory record Official record
Conditions
Bulimia Nervosa, Feeding and Eating Disorders, Mental Disorders
Interventions
Real fNIRS Neurofeedback, Sham-Control fNIRS Neurofeedback, SmartPhone Intervention
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 18, 2026, 12:34 PM EDT