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ClinicalTrials.gov public records Last synced Nov 13, 2026, 10:12 AM EST

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Showing 25–48 of 414 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Active Transcranial Direct Current Stimulation Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Investigating Memory Retrieval Improvement in Healthy Subjects

NCT03312920
View directory record Official record
Conditions
Healthy Adults
Interventions
active anodal tDCS, sham tDCS, active cathodal tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Jan 10, 2025 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Cognitive Enhancement in Depression (The COG-D Study)

NCT05400512
View directory record Official record
Conditions
Aging, Depression, Cognitive Symptom
Interventions
Cognitive Training, tDCS (active stimulation), tDCS (sham stimulation)
Behavioral · Device
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Nov 13, 2026, 10:12 AM EST
Active, not recruiting No phase listed Interventional Results available

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02723929
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
active low-intensity transcranial electrical stimulation/active transcranial ultrasound, Sham low-intensity transcranial electrical stimulation/sham transcranial ultrasound
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Nov 13, 2026, 10:12 AM EST
Recruiting Not applicable Interventional

Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury

NCT06848140
View directory record Official record
Conditions
Traumatic Brain Injury, Word Finding Difficulty, Cognitive Symptom, Cognitive Change, Acquired Brain Injury
Interventions
Active Transcranial direct current stimulation, Sham Transcranial direct current stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2026 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

tDCS for Impulsivity and Compulsivity in Obesity

NCT04405089
View directory record Official record
Conditions
Impulsivity, Compulsive Overeating, Obesity
Interventions
Device: Active Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training, Device: Sham Transcranial Direct Current Stimulation (tDCS) coupled with cognitive training
Device
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 7, 2023 · Synced Nov 13, 2026, 10:12 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Investigating Accelerated Learning in Healthy Subjects: Trigeminal Nerve Stimulation

NCT03138590
View directory record Official record
Conditions
Healthy Adults
Interventions
Transcranial Direct Current Stimulation- Neuroconn DC Stimulator PLUS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional

Effects of tDCS and tUS on Pain Perception in OA of the Knee

NCT02330315
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis
Interventions
transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Nov 13, 2026, 10:12 AM EST
Recruiting Not applicable Interventional

tDCS: Sleep to Mood in Depression (S2M-D)

NCT07572526
View directory record Official record
Conditions
Major Depressive Disorder, MDD, Depression, Major Depressive Episode
Interventions
transcranial direct current stimulation (tDCS)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Nov 13, 2026, 10:12 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

A Neurosensory Account of Anxiety and Stress (Study 1)

NCT05895006
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Intrinsic and Novelty-related Sensory Cortical (SC) Disinhibition
Interventions
Alternating Current Stimulation (tACS), Sham for Transcranial Alternating Current Stimulation (tACS), Transcranial Random Noise stimulation (tRNS)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 50 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Improving Hallucinations by Targeting the rSTS With tES

NCT05165654
View directory record Official record
Conditions
Hallucinations, Auditory, Psychosis
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Nov 13, 2026, 10:12 AM EST
Terminated Not applicable Interventional

Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Severe Post-stroke Hemiparesis

NCT04574973
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
transcranial direct current stimulation, intensive upper extremity motor training
Device · Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Nov 13, 2026, 10:12 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers

Cortical Plasticity Assessment in Athletes With a History of Concussion

NCT01112761
View directory record Official record
Conditions
Concussion
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuromodulation of Lidocaine and Capsaicin Cream Effects on Pain Experience

NCT03102710
View directory record Official record
Conditions
Pain
Interventions
transcranial direct current stimulation (tDCS), Lidocaine cream, Capsaicin cream, Control cream
Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 50 Years
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Nov 13, 2026, 10:12 AM EST
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation Therapy for Central Hypersomnia Without Cataplexy

NCT03198156
View directory record Official record
Conditions
Hypersomnia
Interventions
Transcranial Direct Current Stimulation, Sham stimulation
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 70 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional

tDCS for the Management of Multiple Sclerosis Related Fatigue

NCT03838770
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Active tDCS, sham tDCS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Nov 13, 2026, 10:12 AM EST
Completed Early Phase 1 Interventional

MRI Study of Noninvasive Transcranial Electrical Stimulation in Tinnitus

NCT03544359
View directory record Official record
Conditions
Tinnitus, Subjective
Interventions
Transcranial electrical stimulation (tES)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS) for Post COVID-19 Fatigue

NCT04876417
View directory record Official record
Conditions
Post Covid-19 Patients
Interventions
Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 1, 2024 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

NCT01539109
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Rehabilitation, Noninvasive brain stimulation: tDCS, Sham tDCS: placebo noninvasive brain stimulation
Behavioral · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Repeated Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior

NCT02674516
View directory record Official record
Conditions
Antisocial Behavior, Aggression
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Mindful Breathing and tDCS for Depression

NCT03897699
View directory record Official record
Conditions
Depression, Depressive Disorder
Interventions
Transcranial Direct Current Stimulation, Mindful Breathing, Sham
Device · Behavioral · Other
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years to 24 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 13, 2023 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient

NCT01143649
View directory record Official record
Conditions
Stroke, Healthy
Interventions
transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
Device · Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 90 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Nov 13, 2026, 10:12 AM EST
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation Treatment for Warriors Experiencing Chronic Pain

NCT05254379
View directory record Official record
Conditions
Chronic Pain, Post Traumatic Stress Disorder (PTSD), Depression
Interventions
tDCS
Device
Lead sponsor
Emory University
Other
Eligibility
18 Years to 89 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Nov 13, 2026, 10:12 AM EST
Recruiting Not applicable Interventional

tDCS to Decrease Opioid Relapse (UH3)

NCT06432465
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
active tDCS, sham tDCS
Device
Lead sponsor
Butler Hospital
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Nov 13, 2026, 10:12 AM EST
Recruiting Phase 2 Interventional

tDCS for Post-Stroke Cognitive Impairment

NCT06516588
View directory record Official record
Conditions
Stroke, Mild Cognitive Impairment
Interventions
Transcranial Dirrect Current Stimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Nov 13, 2026, 10:12 AM EST