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Showing 1–24 of 385 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Active Transcranial Direct Stimulation Clear all
Completed Not applicable Interventional

Safety and Feasibility of Tele-supervised Home-based Transcranial Direct Current Stimulation in Parkinson's Disease

NCT06804668
View directory record Official record
Conditions
Parkinson Disease
Interventions
tDCS
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Transcranial Direct Stimulation in Chronic Pelvic Pain

NCT01143636
View directory record Official record
Conditions
Pelvic Pain, Healthy
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Culturally Adapted Mobile Treatment of Chronic Pain in Adolescent Survivors of Pediatric Cancer

NCT05746429
View directory record Official record
Conditions
Bone Sarcoma, Childhood Cancer
Interventions
Cognitive Behavior Therapy, Transcranial Direct Current Stimulation, Placebo Administration, Questionnaire Administration, Interview
Behavioral · Device · Drug + 1 more
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
10 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Results available

Improving Hallucinations by Targeting the rSTS With tES

NCT05165654
View directory record Official record
Conditions
Hallucinations, Auditory, Psychosis
Interventions
Transcranial Electrical Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Before and After Thrombectomy

NCT04061577
View directory record Official record
Conditions
Acute Ischemic Stroke
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Sep 12, 2026, 8:16 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Causal Role of the Aperiodic Signal for Working Memory

NCT06126809
View directory record Official record
Conditions
Executive Dysfunction
Interventions
Steep-tRAS, Flat-tRAS, Sham-tRAS
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 35 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)

NCT02964741
View directory record Official record
Conditions
Migraine
Interventions
Active Comparator, Sham Comparator
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Sep 12, 2026, 8:16 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Brain Stimulation on Stepping Performance in Stroke Survivors and Healthy Adults

NCT04437251
View directory record Official record
Conditions
Vascular Accident, Brain, CVA (Cerebrovascular Accident), Gait, Hemiplegic, Spastic Lower Extremity Weakness
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Texas Woman's University
Other
Eligibility
21 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Results available

Combining Neuro-Imaging and Non-Invasive Brain Stimulation for Clinical Intervention in Opioid Use Disorder

NCT04495673
View directory record Official record
Conditions
Opioid-Related Disorders, Heroin Dependence, Morphine Dependence
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS), Cognitive Training
Device · Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 60 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2025 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Results available

The Use of Transcranial Electrical Stimulation for Hallucinations

NCT02715765
View directory record Official record
Conditions
Schizophrenia
Interventions
Transcranial Direct Current Stimulation, Transcranial Random Noise Stimulation, Transcranial Sham Stimulation
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 64 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Saint Louis Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 25, 2020 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

INSIGHT, A Comprehensive, Multidisciplinary Brain Training System

NCT02780739
View directory record Official record
Conditions
Cognitive Ability, General
Interventions
Cognitive Training - 48 sessions, Fitness, Active Control, active tDCS, sham tDCS, Cognitive Training - 20 sessions
Behavioral · Device
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 44 Years
Enrollment
521 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 22, 2016 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

CONTROL Walking Study

NCT03790657
View directory record Official record
Conditions
Aging
Interventions
practice of a complex walking task, Active transcranial direct current stimulation (Active tDCS), Sham transcranial direct current stimulation (Sham tDCS)
Behavioral · Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Transcranial Direct Current Stimulation (tDCS) and Visual Illusion on Chronic Pain Due to Spinal Cord Injury

NCT01404065
View directory record Official record
Conditions
Chronic Pain, Spinal Cord Injury
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

tDCS-Augmented Exposure Therapy for Pathological Fear

NCT03095482
View directory record Official record
Conditions
Specific Phobias
Interventions
Transcranial Direct Current Stimulation (tDCS), In vivo exposure therapy
Device · Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2020 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study

NCT02512393
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
45 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Sep 12, 2026, 8:16 PM EDT
Withdrawn Not applicable Interventional

Investigating HD-tDCS in Improving Word Finding and Memory Retrieval in Individuals With MCI

NCT03446508
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Active frontal, Active parietal, Sham
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
40 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Sep 12, 2026, 8:16 PM EDT
Terminated Not applicable Interventional

Modulating Neuropathic Pain With Transcranial Direct Current Stimulation

NCT04581525
View directory record Official record
Conditions
Pain, Neuropathic, Complex Regional Pain Syndromes, Phantom Limb Pain, Spinal Cord Injuries
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Susan McDowell
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 13, 2021 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional

A Study of Cerebral Perfusion With tDCS in Chronic Hypoperfusion

NCT06477107
View directory record Official record
Conditions
Moyamoya Syndrome, Moyamoya Disease, Atheroscleroses, Cerebral
Interventions
Soterix® 4x1HD-TDCS, Soterix® 1x1 tDCS, Cognitive training program
Device · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Recruiting Not applicable Interventional

Non-invasive Brain Stimulation Using Tdcs of the Third (of Many) Visual Pathways

NCT07469384
View directory record Official record
Conditions
SCHIZOPHRENIA 1 (Disorder), Schizo Affective Disorder
Interventions
transcranial direct current stimulation, Sham stimulation
Device
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Recruiting Not applicable Interventional

Home-Based tDCS Treatment Of Major Depressive Disorder

NCT06976697
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Transcranial direct current stimulation, Sham transcranial direct current stimulation
Device
Lead sponsor
Sooma Medical Inc
Industry
Eligibility
22 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional

TDCS for Cocaine Addiction Craving

NCT03833583
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence
Interventions
Soterix Medical mini-CT tDCS stimulator
Device
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2024 · Synced Sep 12, 2026, 8:16 PM EDT
Withdrawn Not applicable Interventional

Non-invasive Brain Stimulation in Children With Autism

NCT05105126
View directory record Official record
Conditions
Autism Spectrum Disorder, Executive Dysfunction, Child Autism
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham tDCS
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
5 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 12, 2026, 8:16 PM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation (tDCS)

NCT05524233
View directory record Official record
Conditions
Brain Fog
Interventions
Active Transcranial Direct Stimulation
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2025 · Synced Sep 12, 2026, 8:16 PM EDT
Active, not recruiting No phase listed Interventional Results available

Effects of tDCS and TUS on the Perception of Pain and Functional Limitations Due to Non-Specific Chronic Low Back Pain

NCT02954432
View directory record Official record
Conditions
Chronic Pain, Chronic Low Back Pain
Interventions
transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Sep 12, 2026, 8:16 PM EDT