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ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:47 PM EDT

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Showing 1–24 of 82 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Active neurofeedback Clear all
Terminated Not applicable Interventional Results available

Circuitry Assessment and Reinforcement Training Effects on Recovery

NCT04290988
View directory record Official record
Conditions
Aphasia, Primary Progressive Aphasia, Stroke
Interventions
EEG Neurofeedback, Sham Feedback
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Neurofeedback to Treat Depression - 2

NCT07159061
View directory record Official record
Conditions
Major Depressive Disorder (MDD)
Interventions
Active Closed Loop Real Time fMRI Neurofeedback, Sham Closed Loop Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Responsiveness to Acute Changes in Exercise and Relaxation (RACER) Trial

NCT03702712
View directory record Official record
Conditions
Breast Cancer
Interventions
Aerobic Exercise and Relaxation, Aerobic Exercise Only, Relaxation Only
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 120 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2019 · Synced Sep 2, 2026, 5:47 PM EDT
Active, not recruiting Not applicable Interventional

Neurofeedback to Improve Working Memory in Mild Cognitive Impairment

NCT04566900
View directory record Official record
Conditions
Mild Cognitive Impairment
Interventions
Neurofeedback, Placebo
Behavioral · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years to 85 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Emotion Study/Substudy: Flexible Brain Study

NCT03872414
View directory record Official record
Conditions
Aging, Emotions, Parkinson Disease
Interventions
Anterior cingulate cortex activation, Primary auditory cortex activation
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Neurofeedback During Eating for Bulimia Nervosa

NCT05614024
View directory record Official record
Conditions
Bulimia Nervosa
Interventions
Real fNIRS Neurofeedback, Sham-Control fNIRS Neurofeedback
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Neurofeedback During Naturalistic Stimuli to Reduce Craving in Heroin Addiction

NCT07344233
View directory record Official record
Conditions
Opioid Use Disorder, Substance Use Disorder, Heroin Use Disorder
Interventions
Real-time fMRI Neurofeedback, Sham Real-time fMRI Neurofeedback
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional

A Trial of Neurofeedback as an Adjunctive Treatment for Youth in Outpatient Mental Health Settings

NCT04871009
View directory record Official record
Conditions
Trauma
Interventions
Neurofeedback Intervention, standard of care
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
6 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Not yet recruiting Not applicable Interventional

Frontal Gamma Coherence Neurofeedback for Patients With Schizophrenia

NCT07659938
View directory record Official record
Conditions
Schizophrenia, Schizoaffective
Interventions
Frontal gamma coherence neurofeedback, Placebo Neurofeedback
Behavioral
Lead sponsor
BioSignal Solutions LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Neurofeedback Impact on Veterans With mTBI

NCT04195685
View directory record Official record
Conditions
Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache, Chronic Insomnia, Chronic Attention Disorder
Interventions
Neurofeedback (NFB)
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 2, 2026, 5:47 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

DecNef for AVH in Schizophrenia

NCT07779226
View directory record Official record
Conditions
Schizophrenia Disorder, Schizoaffecitve Disorder
Interventions
Decoded Neurofeedback
Device
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)

NCT07252011
View directory record Official record
Conditions
Adults With Variability in Their Mood
Interventions
Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall, Physiological stimulation
Device · Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Amygdala Neurofeedback for Depression - Large Scale Clinical Trial

NCT05703256
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Amygdala real-time fMRI neurofeedback, Sham feedback
Device
Lead sponsor
Kymberly Young
Other
Eligibility
18 Years to 55 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression

NCT05933148
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Siemens 7T MRI, Sham Neurofeedback
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional

Neurofeedback to Treat Depression

NCT05169346
View directory record Official record
Conditions
MDD
Interventions
Active Closed Loop Real Time fMRI Neurofeedback, Sham Closed Loop Real Time fMRI Neurofeedback
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Results available

Effect of Amygdala Neurofeedback on Depressive Symptoms and Processing Biases

NCT02079610
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
real-time fMRI neurofeedback: Amygdala, real-time fMRI neurofeedback: HIPS
Behavioral
Lead sponsor
Laureate Institute for Brain Research, Inc.
Other
Eligibility
18 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mindful Minds: Mindfulness-Based Neurofeedback for Underrepresented College Students

NCT06784934
View directory record Official record
Conditions
Academic Performance, Anxiety
Interventions
NeuroSky Mindfulness-Based Neurofeedback
Device
Lead sponsor
Florida International University
Other
Eligibility
18 Years to 30 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmenting Mindfulness Training Through Experience-driven Neurofeedback

NCT02413177
View directory record Official record
Conditions
Stress
Interventions
EEG-no RTNF, EEG-RTNF
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years to 60 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2018 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy

NCT07122739
View directory record Official record
Conditions
Healthy
Interventions
Active Real-time fMRI Neurofeedback, Sham Real-time fMRI neurofeedback
Behavioral
Lead sponsor
Trustees of Princeton University
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Princeton, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 22, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Stanford Center for Back Pain

NCT02503475
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Real-Time fMRI, CBT or MBSR, Acupuncture
Other · Behavioral · Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2024 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Neurofeedback From the Supplementary Motor Area for Tourette Syndrome

NCT05558566
View directory record Official record
Conditions
Tourette Syndrome in Adolescence
Interventions
Neurofeedback from the SMA, Neurofeedback from control region
Other
Lead sponsor
Yale University
Other
Eligibility
10 Years to 16 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Network Modulation and Alcohol Use

NCT04828577
View directory record Official record
Conditions
Alcohol Use Disorder (AUD)
Interventions
Real Time Neurofeedback
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
21 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 2, 2026, 5:47 PM EDT
Completed No phase listed Observational

Chronic Pain and Brain Activity in Spinal Cord Injury

NCT01012635
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Hypnosis, Meditation, Neurofeedback training, Two different levels of tDCS
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Sep 2, 2026, 5:47 PM EDT
Recruiting Not applicable Interventional

Modulating Neurocognitive Processes of Learning to Trust and Distrust in Aging

NCT05457725
View directory record Official record
Conditions
Aging, Cognitive Change, Neurocognitive Disorders, Mild
Interventions
Contingent rtfMRI neurofeedback training, Non-contingent/sham rtfMRI neurofeedback training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 2, 2026, 5:47 PM EDT