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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Active tDCS + Language Therapy Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive Aphasia

NCT04486586
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Remotely-supervised Neuromodulation in PPA

NCT07260253
View directory record Official record
Conditions
Primary Progressive Aphasia(PPA), Progressive Aphasia, Progressive Aphasia in Alzheimer's Disease, Logopenic Progressive Aphasia (LPA), Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA)
Interventions
Lexical Retrieval Cascade Treatment, Remotely Supervised Transcranial Direct Current Stimulation- Active, Remotely Supervised Transcranial Direct Current Stimulation - Sham
Behavioral · Device
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Francisco, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Enhancing Language Function in Primary Progressive Aphasia

NCT04920318
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
tDCS + language therapy, sham TDCS + language therapy
Combination Product
Lead sponsor
University of Arizona
Other
Eligibility
45 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

NCT04142866
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

NCT05386394
View directory record Official record
Conditions
Primary Progressive Aphasia, Logopenic Progressive Aphasia, Non-Fluent Primary Progressive Aphasia
Interventions
Active tDCS + Language Therapy, Sham tDCS + Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Neurostimulation for the Treatment of Post-Stroke Aphasia

NCT05194566
View directory record Official record
Conditions
Post-stroke Aphasia
Interventions
tACS
Device
Lead sponsor
QVITI S.A.
Industry
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy

NCT03728582
View directory record Official record
Conditions
Primary Progressive Aphasia, PPA
Interventions
Active tDCS plus Speech-Language Therapy, Sham tDCS plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Clinical Feasibility of Transcranial Direct Current Stimulation [tDCS] With Standard Aphasia Therapy

NCT03272906
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-language therapy
Device · Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Primary Progressive Aphasia

NCT02928848
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
transcranial direct current stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

NCT04432883
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active Comparator: Experimental: Active cathodal tDCS + language training, Sham Comparator: Placebo cathodal tDCS + Speech and language
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
25 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Phase 2 Interventional

Treating Primary Progressive Aphasia (PPA) Using High-definition tDCS

NCT04046991
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
high-definition transcranial direct current stimulation, modified constraint-induced language therapy
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Improving Aphasia Using Electrical Brain Stimulation

NCT04963803
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active transcranial direct current stimulation (tDCS), Sham transcranial direct current stimulation (tDCS), Language Specific Attention Treatment
Device · Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Phase 1Phase 2 Interventional

Result of tDCS in ASD Children With Comorbidities Like PANDAS, Rare Genetic Diseases or Autoimmune Disorders

NCT06368726
View directory record Official record
Conditions
Attention, Visual Perceptual Weakness, Social Behavior, Fluency Disorder, EEG With Periodic Abnormalities
Interventions
tDCS or Transcranial Direct Current Stimulation, Risperidone, Sham tDCS
Device · Drug · Other
Lead sponsor
Spanish Foundation for Neurometrics Development
Other
Eligibility
6 Years to 11 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 9, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Effects of Transcranial Direct Current Stimulation (tDCS) on Language

NCT04166513
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Targeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy, Semantic-Focused Speech Therapy
Device · Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

tDCS Intervention in Primary Progressive Aphasia

NCT02606422
View directory record Official record
Conditions
Primary Progressive Aphasia, MCI, FTD
Interventions
Active HD-tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

NCT03887481
View directory record Official record
Conditions
Logopenic Progressive Aphasia, Primary Progressive Aphasia
Interventions
High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment, Sham + "Repeat After Me" (RAM) Treatment
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2018 · Synced Sep 12, 2026, 4:09 AM EDT
Active, not recruiting Not applicable Interventional

Treatment Outcomes With tDCS in Post-Stroke Aphasia

NCT03929432
View directory record Official record
Conditions
Aphasia
Interventions
Active Transcranial Direct Current Stimulation with SLT, Sham Transcranial Direct Current Stimulation with SLT
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2029
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

NCT06891638
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Schedule of tDCS administration
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Phase 2 Interventional Results available

Dextroamphetamine and tDCS to Improve the Fluency

NCT02514044
View directory record Official record
Conditions
Stroke
Interventions
Dexedrine, Active tDCS, Speech Therapy, Placebo, Sham tDCS
Drug · Device · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Sep 12, 2026, 4:09 AM EDT
Recruiting Not applicable Interventional

Brain Stimulation Effects on Post-Stroke Fatigue and Aphasia

NCT07151677
View directory record Official record
Conditions
Aphasia Following Cerebral Infarction, Stroke Ischemic, Fatigue Symptom
Interventions
tDCS (active), Attention-focused sentence comprehension treatment, Sentence comprehension treatment, tDCS (sham)
Device · Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Ann Arbor, Michigan • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Sep 12, 2026, 4:09 AM EDT
Completed Not applicable Interventional Results available

Stimulating Language in Subacute StrokE

NCT02674490
View directory record Official record
Conditions
Stroke
Interventions
A-tDCS (1 mA), SALT, Sham
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 12, 2026, 4:09 AM EDT