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ClinicalTrials.gov public records Last synced Oct 18, 2026, 12:34 PM EDT

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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Acute Stressors Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Neural Control of Kidney Blood Flow During Exercise in African American Adults

NCT03981640
View directory record Official record
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 35 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?

NCT02972554
View directory record Official record
Conditions
Stress, Psychological, Inflammation, Cortisol, Sympathetic Nervous System
Interventions
Propanolol hydrochloride, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 25 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 18, 2026, 12:34 PM EDT
Not listed Not applicable Interventional

Smart Technology for Anorexia Nervosa Recovery

NCT05190926
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Smart-Treatment for Anorexia Nervosa Recovery (STAR), Present-focused Anorexia Nervosa Coping Treatment (PACT)
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
13 Years to 21 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 18, 2026, 12:34 PM EDT
Enrolling by invitation Not applicable Interventional

Personalizing Treatment Delivery

NCT05821634
View directory record Official record
Conditions
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
Interventions
Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Stress and Anxiety Effects on Valuation

NCT07252947
View directory record Official record
Conditions
Reward Value Level
Interventions
Socially Evaluated Cold Pressor Task (SECPT), Non-Stressful Control Task
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stress Reactivity Study in Adolescents

NCT03997149
View directory record Official record
Conditions
Stress, Eating Behavior
Interventions
Acute Laboratory Stressor, Low affect video
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 19 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cerebrovascular Health and Resilience in Midlife

NCT06029348
View directory record Official record
Conditions
Psychological Stress, Cardiovascular Diseases, Cerebrovascular Disorders
Interventions
Paced Auditory Serial Addition Task
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
40 Years to 59 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Active, not recruiting Not applicable Interventional

Building Resiliency in Dyads of Patients With an ANI Admitted to the Neuro-ICU and Their Informal Caregivers

NCT05157880
View directory record Official record
Conditions
Acute Neurological Injury, Emotional Distress
Interventions
Recovering Together
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress

NCT05413512
View directory record Official record
Conditions
Acute Psychological Stress
Interventions
Acute psychological stress
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 30 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

Intensive Crisis Intervention

NCT06476886
View directory record Official record
Conditions
Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm, Suicide Threat
Interventions
Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
Behavioral
Lead sponsor
Jennifer Hughes
Other
Eligibility
12 Years to 17 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Recruiting Not applicable Interventional

Resilience Among Individuals With Opioid Use Disorder

NCT06954402
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Acute Stress Intervention (MAST-based), Non-Stress Intervention (NST-based)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Acceptability of Mindfulness-based Resilience Training for Rural Law Enforcement Officers

NCT05629637
View directory record Official record
Conditions
Problem Drinking, Aggression, Stress, Psychological
Interventions
Mindfulness-Based Resilience Training (MBRT)
Behavioral
Lead sponsor
Pacific University
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Forest Grove, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 18, 2026, 12:34 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Smoking, Stress & Allopregnanolone Response

NCT02087800
View directory record Official record
Conditions
Smoking Cessation
Interventions
F phase lab session, L phase lab session
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 30, 2015 · Synced Oct 18, 2026, 12:34 PM EDT
Terminated Phase 3 Interventional Results available

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge - 2

NCT05011396
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
PH94B Nasal Spray, Placebo Nasal Spray
Drug
Lead sponsor
VistaGen Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
15
States / cities
Phoenix, Arizona • Garden Grove, California • Oceanside, California + 12 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional

Using CBT to Probe Psychobiobehavioral Resilience to Post-trauma Psychopathology

NCT02279290
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Healthy Mind Intervention (HMI), Healthy Body Intervention (HBI)
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress and the Sympathetic Nervous System in Adults With Depression

NCT04838262
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Acute Stressors
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 30 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Kidney Blood Flow During Exercise in Older African American Adults

NCT07029165
View directory record Official record
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Phase 3 Interventional Results available

PH94B Nasal Spray for Anxiety Induced by a Public Speaking Challenge

NCT04754802
View directory record Official record
Conditions
Social Anxiety Disorder
Interventions
PH94B Nasal Spray, Placebo Nasal Spray
Drug
Lead sponsor
VistaGen Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
21
States / cities
Los Angeles, California • Orange, California • Riverside, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stress, Sex, and the Generalization of Fear

NCT03786952
View directory record Official record
Conditions
Psychological Stress
Interventions
Stress immediately before learning in males, Sham control immediately before learning in males, Stress 30 minutes before learning in males, Sham control 30 minutes before learning in males, Stress immediately before learning in females, Sham control immediately before learning in females, Stress 30 minutes before learning in females, Sham control 30 minutes before learning in females
Behavioral
Lead sponsor
Ohio Northern University
Other
Eligibility
18 Years and older
Enrollment
606 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ada, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Decision Making, Daily Experiences, and Brain Activity in Young Adult Women

NCT04125589
View directory record Official record
Conditions
Binge-Eating Disorder
Interventions
Speaking Activity, Talking Activity
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Stress-Induced Inflammation and Reward Processing

NCT03828604
View directory record Official record
Conditions
Stress, Psychological
Interventions
Stress; Trier Social Stress Task, Placebo Trier Social Stress Task
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 28 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 18, 2026, 12:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Transcutaneous Auricular Neurostimulation on Cognitive Performance in a Laboratory Model of Acute Stress Reaction

NCT06390267
View directory record Official record
Conditions
Acute Stress Reaction, Cognitive Performance
Interventions
Sparrow Hawk (Active), Sparrow Hawk (Sham)
Device
Lead sponsor
Spark Biomedical, Inc.
Industry
Eligibility
18 Years to 41 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 1, 2025 · Synced Oct 18, 2026, 12:34 PM EDT