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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Conditions
Post-Traumatic Stress Disorder
Interventions
Treatment as Usual, Virtual Reality Exposure with Stimulus Control
Behavioral
Lead sponsor
Office of Naval Research (ONR)
Federal
Eligibility
18 Years to 65 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
2
States / cities
Camp Pendlton, California • San Diego, California
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
Psilocybin 25 mg, Maltodextrin (Placebo)
Drug
Lead sponsor
Nathan Brashares Sackett
Other
Eligibility
21 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Exercise, Cognition
Interventions
Aerobic Exercise Intervention, Trier Social Stress Test for Children, Seated Rest
Other
Lead sponsor
Northeastern University
Other
Eligibility
9 Years to 10 Years
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Neural Control of Kidney Blood Flow During Exercise in African American Adults

NCT03981640
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
18 Years to 35 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Does Propranolol Attenuate Inflammatory Responses to a Psychological Stressor?

NCT02972554
Conditions
Stress, Psychological, Inflammation, Cortisol, Sympathetic Nervous System
Interventions
Propanolol hydrochloride, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 25 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Trauma and Cardiometabolic Health in an American Indian Community

NCT06878885
Conditions
Psychological Stress, Cardiometabolic Conditions, Mental Health
Interventions
Acute psychological stress task (Paced Auditory Serial Addition Task)
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 40 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Browning, Montana
Conditions
Adolescent Development, Stress, Emotional Disturbances
Interventions
Trier Social Stress Test, Emotional go/no-go task
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
11 Years to 14 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Stress-induced Scratching in Healthy and AD

NCT04174651
Conditions
Healthy, Atopic Dermatitis
Interventions
Trier Social Stress Test (TSST), Landscape Video
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 59 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Miami, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Stress Reactivity Study in Adolescents

NCT03997149
Conditions
Stress, Eating Behavior
Interventions
Acute Laboratory Stressor, Low affect video
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 19 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Recruiting No phase listed Observational Accepts healthy volunteers

MicroRNA Correlates of Childhood Maltreatment and Suicidality

NCT04923685
Conditions
Major Depressive Disorder, Suicidal Ideation
Interventions
Trier Social Stress Test
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 60 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
2
States / cities
Birmingham, Alabama • Huntsville, Alabama
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)

NCT02115724
Conditions
Cardiovascular Disease
Interventions
Antioxidant cocktail, Biopsy, Placebo, NMD; 0.4mg sub-lingual nitroglycerin spray
Dietary Supplement · Other · Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 40 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Stress, Mental Stress
Interventions
Melatonin 3 MG Oral Tablet, Placebo Oral Tablet
Dietary Supplement
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 70 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Waco, Texas
Conditions
Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
Interventions
Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, Matching Oral Placebo, Matching Intramuscular Placebo, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform, Standardized Psychological Preparation, Integration and Recovery Support, Garmin-Enabled Longitudinal Wellness Monitoring
Drug · Device · Behavioral + 1 more
Lead sponsor
Clive Michelsen
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Basalt, Colorado
Completed Not applicable Interventional Accepts healthy volunteers Results available

Stressor-evoked Brain and Cardiovascular Responses to Acute Psychological Stress

NCT05413512
Conditions
Acute Psychological Stress
Interventions
Acute psychological stress
Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 30 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Waco, Texas
Conditions
Intensive Care Unit Survivors, Informal Caregivers (Family and Friends)
Interventions
coping skills training, education program
Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
4
States / cities
Chapel Hill, North Carolina • Durham, North Carolina • Pittsburgh, Pennsylvania + 1 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Kidney Blood Flow During Exercise in Older African American Adults

NCT07029165
Conditions
Healthy
Interventions
Acute exercise, Cold pressor test, Mental stress test
Other
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Acute Psychological and Physiological Effects of Cannabigerol

NCT06638996
Conditions
No Disease or Condition is Being Studied
Interventions
CBG Intervention, Placebo Intervention
Dietary Supplement · Other
Lead sponsor
Washington State University
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Pullman, Washington
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Acceptance and Commitment Therapy for the Inpatient Treatment of Psychosis

NCT01981356
Conditions
Psychotic Disorders
Interventions
Acceptance and Commitment Therapy, Treatment as Usual (TAU)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Type 1 Diabetes
Interventions
Not listed
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
20 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
PTSD, Cognitive Performance
Interventions
Cognitive Processing Therapy, Eye-Movement Desensitization and Reprocessing
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fayetteville, North Carolina
Completed Phase 1Phase 2 Interventional

Study Targeting Affect Regulation

NCT01237366
Conditions
HIV, AIDS, Substance Use Disorders
Interventions
Resilient Affective Processing Therapy (RAPT)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Francisco, California
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Disrupted Connections: The Impact of Acute Stress on Memory Integration

NCT07055555
Conditions
Stress, Control Condition
Interventions
Acute Stress, Non-Stress Control Task
Behavioral
Lead sponsor
Nevada State University
Other
Eligibility
18 Years to 35 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Henderson, Nevada
Conditions
PTSD, Trauma, Pediatric ALL
Interventions
Emotion Regulation, Exposure, Cognitive Processing, Bi-lateral Stimulation, Psychological Placebo
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
8 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, New York
Terminated No phase listed Observational Accepts healthy volunteers

Stress and Anxiety Effects on Overactive Bladder

NCT05087810
Conditions
Overactive Bladder, Stress, Psychological, Anxiety
Interventions
Psychological stress induction, Accelerated oral hydration
Behavioral · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Nashville, Tennessee