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ClinicalTrials.gov public records Last synced Nov 6, 2026, 12:41 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.

Filters: Intervention: Acuvue Oasys Clear all

Conditions: Myopia
Interventions: kalifilcon A, delefilcon A, senofilcon A; Device
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years to 40 Years
Enrollment: 805 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 35
States / cities: Birmingham, Alabama • Scottsdale, Arizona • Azusa, California + 31 more

Conditions: Visual Acuity
Interventions: Acuvue Oasys 1 Day for Astigmatism, TRA100/TRA200 series toric contact lens with HEVL-blocking chromophore; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 39 Years
Enrollment: 188 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023
U.S. locations: 10
States / cities: Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 7 more

Conditions: Visual Acuity
Interventions: ACUVUE Oasys 1-Day, Habitual Lens; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 59 Years
Enrollment: 95 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 9
States / cities: Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more

Conditions: Contact Lens
Interventions: Daily Disposable Contact Lens; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Lid Wiper Epitheliopathy
Interventions: Acuvue Oasys, Air Optix Night & Day Aqua; Device
Lead sponsor: University of Houston; Other
Eligibility: 18 Years to 46 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Photophobia, Visual Impairment, Low Vision
Interventions: Acuvue Oasys with Transitions; Device
Lead sponsor: Nova Southeastern University; Other
Eligibility: 18 Years to 64 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Davie, Florida

Conditions: Visual Acuity
Interventions: soft contact lens in senofilcon A (C3) with HEVL-blocking chromophore, ACUVUE OASYS 1-Day for Astigmatism; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 39 Years
Enrollment: 126 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 10
States / cities: Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more

Conditions: Contact Lens Complication
Interventions: Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A); Device
Lead sponsor: ORA, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014
U.S. locations: 1
States / cities: Andover, Massachusetts

Conditions: Refractive Ametropia
Interventions: Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 190 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 15
States / cities: Los Angeles, California • Oakland, California • San Francisco, California + 11 more

Conditions: Visual Performance
Interventions: TRP-200, ACUVUE Oasys 1-Day; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 82 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Athens, Georgia

Conditions: Refractive Errors
Interventions: Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 5
States / cities: Maitland, Florida • Medina, Minnesota • Granville, Ohio + 2 more

Conditions: Conjunctival Staining
Interventions: Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Contact Lens Comfort
Interventions: senofilcon A; Device
Lead sponsor: Ohio State University; Other
Eligibility: 8 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Visual Acuity
Interventions: B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 39 Years
Enrollment: 85 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 4
States / cities: Roswell, Georgia • New Bremen, Ohio • Salem, Virginia + 1 more

Conditions: Myopia
Interventions: PureVision Contact Lens, Acuvue Oasys Contact Lens, O2Optix Contact lens; Device
Lead sponsor: Bausch & Lomb Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 510 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Refractive Error
Interventions: Delefilcon A contact lenses, Senofilcon A contact lenses; Device
Lead sponsor: Alcon, a Novartis Company; Industry
Eligibility: 18 Years and older
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Refractive Errors, Myopia, Hypermetropia
Interventions: Lotrafilcon B contact lenses with added wetting agent, Samfilcon A contact lenses, POLYQUAD/ALDOX-preserved contact lens solution with added wetting agent, Hydrogen peroxide-based contact lens solution with added wetting agent, Senofilcon C contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Habitual Multi-Purpose Solution (HMPS); Device
Lead sponsor: Alcon, a Novartis Company; Industry
Eligibility: 18 Years and older
Enrollment: 323 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 5
States / cities: Birmingham, Alabama • Cleveland, Ohio • Columbus, Ohio + 2 more

Conditions: Ametropia
Interventions: senofilcon A toric, alphafilcon A toric; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008
U.S. locations: 7
States / cities: Jacksonville, Florida • Orlando, Florida • Morrow, Georgia + 4 more

Conditions: Refractive Errors, Ametropia
Interventions: Lehfilcon A contact lenses, Senofilcon A contact lenses, Comfilcon A contact lenses, Hydrogen peroxide-based cleaning and disinfecting solution; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 4
States / cities: Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more

Conditions: Contact Lens Comfort
Interventions: Precision 7 contact lenses; Device
Lead sponsor: Southern College of Optometry; Other
Eligibility: 18 Years to 40 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Visual Acuity
Interventions: TRP-200, JJVC Marketed Contact Lens; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 39 Years
Enrollment: 228 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 12
States / cities: Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 9 more

Conditions: Refractive Errors
Interventions: DT1 Toric contact lenses, AO1DfA contact lenses; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 2
States / cities: Maitland, Florida • Eden Prairie, Minnesota

Conditions: Visual Acuity
Interventions: Spectacles, ACUVUE OASYS®1-Day with HydraLuxe™ Technology; Device
Lead sponsor: Johnson & Johnson Vision Care, Inc.; Industry
Eligibility: 18 Years to 42 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 3
States / cities: Jacksonville, Florida • Longwood, Florida • New York, New York

Conditions: Contact Lens Wettability
Interventions: FID 114675A multi-purpose disinfecting solution (MPDS), Soft contact lens, Blister pack solution; Device
Lead sponsor: Alcon Research; Industry
Eligibility: 18 Years and older
Enrollment: 66 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Fort Worth, Texas

Search by objective public record fields.

Product Performance of a New Silicone Hydrogel Contact Lens

Design Validation of Toric Contact Lenses in Senofilcon A With a Blue-Blocking Chromophore

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

Evaluation of Wear Experience With a Daily Disposable Contact Lens

The Impact of Contact Lens Coefficient of Friction (CoF) on the Development of Lid Wiper Epitheliopathy (LWE)

Improving Glare and Visual Comfort for Patients With Visual Impairment

Evaluation of Toric Soft Contact Lenses Containing a Chromophore to Block High-Energy Visible Light

A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses

The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses

Visual Performance of Senofilcon A With and Without a New UV/HEV-filter

Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses

Evaluation of Contact Lenses and Conjunctival Staining in Normal Patients

Contact Lens Adaptation in Neophytes

Evaluation of Approved Contact Lenses

Comparative Performance of PureVision, Acuvue Oasys and O2Optix

ACUVUE® OASYS® 1-DAY vs DAILIES TOTAL1®

Clinical Assessment of a HYDRAGLYDE® Regimen

Comparison of Two Toric Contact Lenses on Current Toric Wearers

Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses

Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses

Evaluation of Prototype Lenses With Experimental UV/HEV Blocker

Clinical Performance Evaluation of Two Daily Disposable Silicone Hydrogel Toric Contact Lenses

Ocular Characteristics in Contact Lens and Spectacle Wear

Effect of FID 114675A on Lens Wettability