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ClinicalTrials.gov public records Last synced Sep 27, 2026, 7:39 AM EDT

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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers

NCT06333613
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
13 Years to 39 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
5
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 2 more
Conditions
Astigmatism
Interventions
Test Lens, Control Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
12
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 9 more
Completed Not applicable Interventional Accepts healthy volunteers

PAVES Benchmarking Pilot Study of Daily Disposable Contact Lenses

NCT04032457
Conditions
Refractive Errors
Interventions
Phase A - olifilcon B with Tangible Coatings, Phase B - etafilcon A with Tangible Coatings
Device
Lead sponsor
Vision Service Plan
Industry
Eligibility
18 Years to 42 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
6
States / cities
Atlanta, Georgia • Niles, Illinois • Carmel, Indiana + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of ACUVUE OASYS® 1-Day for Astigmatism Lenses Produced on a New Manufacturing Line

NCT04794270
Conditions
Visual Acuity
Interventions
ACUVUE OASYS® 1-Day for Astigmatism - TAM 24, ACUVUE OASYS® 1-Day for Astigmatism
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
5
States / cities
Longwood, Florida • Bloomington, Illinois • Pittsburg, Kansas + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Dryness in a Silicone Hydrogel Daily Disposable Contact Lens

NCT04849780
Conditions
Visual Acuity
Interventions
ACUVUE Oasys 1-Day, Habitual Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 59 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
9
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 6 more
Conditions
Presbyopia
Interventions
Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
8
States / cities
Los Angeles, California • Oakland, California • Maitland, Florida + 5 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Contact Lens Insertion and Removal in a Senior Subject Demographic

NCT03597178
Conditions
Visual Acuity
Interventions
senofilcon A
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
60 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Prototype Lenses With Experimental UV/HEV Blocker

NCT04885296
Conditions
Visual Acuity
Interventions
TRP-200, JJVC Marketed Contact Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
12
States / cities
Jacksonville, Florida • Orange Park, Florida • Tallahassee, Florida + 9 more
Conditions
Refractive Errors
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
5
States / cities
Maitland, Florida • Medina, Minnesota • Granville, Ohio + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of a Daily Wear Reusable Multifocal Optical Design in a Presbyopic Population

NCT04534517
Conditions
Visual Acuity
Interventions
JJV Investigational Multifocal Contact Lens, ACUVUE OASYS® with HYDRACLEAR® PLUS
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
40 Years to 70 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
11
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 8 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design Validation of Senofilcon A With New UV-blocking Additive

NCT03707821
Conditions
Visual Acuity
Interventions
senofilcon A TEST Lens, senofilcon A CONTROL Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
10
States / cities
Cupertino, California • Maitland, Florida • Tallahassee, Florida + 7 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effects of Contact Lenses With UV/HEV-Filter on Visual Function

NCT05601544
Conditions
Visual Acuity
Interventions
ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal, ACUVUE OASYS MAX 1-Day Multifocal, ACUVUE OASYS 1-Day for Astigmatism, senofilcon A based contact lens (toric) with new UV/HEV filter
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Athens, Georgia
Completed Not applicable Interventional Results available

Two Daily Disposable Contact Lenses in Symptomatic Patients

NCT03628599
Conditions
Myopia
Interventions
Delefilcon A contact lenses, Senofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Bloomington, Illinois • Pittsburg, Kansas • Powell, Ohio + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Design Validation of Toric Contact Lenses in Senofilcon A With a Blue-Blocking Chromophore

NCT05778786
Conditions
Visual Acuity
Interventions
Acuvue Oasys 1 Day for Astigmatism, TRA100/TRA200 series toric contact lens with HEVL-blocking chromophore
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 39 Years
Enrollment
188 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
10
States / cities
Jacksonville, Florida • Longwood, Florida • Maitland, Florida + 7 more
Completed Not applicable Interventional Results available

Feasibility of a New Silicone Hydrogel Lens

NCT01131130
Conditions
Myopia
Interventions
Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Rochester, New York
Conditions
Contact Lens Complication
Interventions
Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
Device
Lead sponsor
ORA, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Andover, Massachusetts
Conditions
Myopia
Interventions
Biweekly replacement contact lenses, One week replacement contact lenses
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Ametropia, Myopia, Hyperopia, Astigmatism
Interventions
Serafilcon A toric contact lenses, Senofilcon A toric contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
7
States / cities
Oakland, California • San Francisco, California • Maitland, Florida + 4 more
Withdrawn Not applicable Interventional Accepts healthy volunteers

Healing of Persistent Epithelial Defects

NCT02395952
Conditions
Cornea
Interventions
carboxymethylcellulose sodium, Acuvue Oasys Bandage Contact Lens, Ambiodisk, Prokera
Drug · Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Initial Evaluation of Investigational Lenses Manufactured on a New Production Line

NCT03679741
Conditions
Visual Acuity
Interventions
CONTROL Lens, TEST Lens
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 49 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
6
States / cities
San Francisco, California • Jacksonville, Florida • Vestal, New York + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Visual Performance of Senofilcon A With and Without a New UV/HEV-filter

NCT05021081
Conditions
Visual Performance
Interventions
TRP-200, ACUVUE Oasys 1-Day
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Conjunctival Staining
Interventions
Complete Easy Rub, ReNu MultiPlus, Clear Care, Contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Corneal Epithelial Wound
Interventions
Acuvue Oasys, Ocular Bandage Gel
Device
Lead sponsor
Eyegate Pharmaceuticals, Inc.
Industry
Eligibility
22 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

Clinical Comparison of 4 Daily Disposable Soft Contact Lenses

NCT03349632
Conditions
Refractive Error
Interventions
verofilcon A contact lenses, senofilcon A contact lenses, stenfilcon A contact lenses, etafilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
3
States / cities
Maitland, Florida • Pensacola, Florida • Johns Creek, Georgia