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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:14 PM EDT

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Showing 49–72 of 172 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Adaptive Goals Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Studying the Effects of Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults

NCT06633978
View directory record Official record
Conditions
MCI, Aging
Interventions
MediTrain, wrist worn multi-sensor watches, Sleep monitor
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years to 85 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Improving Brief Alcohol Interventions With a Behavioral Economic Supplement

NCT02834949
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Brief Motivational Intervention (BMI), Substance-Free Activity Session (SFAS), Relaxation Session
Behavioral
Lead sponsor
University of Memphis
Other
Eligibility
18 Years to 27 Years
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Columbia, Missouri • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Reminder Focused Positive Psychiatry in Adolescents With ADHD and PTSD

NCT04336072
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Attention Deficit Hyperactivity Disorder
Interventions
RFPP, TFCBT
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
9 Years to 18 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Daily Goal Setting to Increase Everyday Physical Activity and Promote Cognitive Health in Midlife

NCT05826379
View directory record Official record
Conditions
Physical Inactivity, Walking, Cognitive Health, Self-regulation, Overweight and Obesity
Interventions
Adaptive Daily Goal Setting, Interim Goal Prompt
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
30 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Virtual Reality, Debriefing and Chronic Pain

NCT05254509
View directory record Official record
Conditions
Chronic Pain
Interventions
Occupational Therapy, Occupational Therapy +Virtual Reality
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Oct 21, 2026, 8:14 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

NCT05320822
View directory record Official record
Conditions
Concussion, Brain
Interventions
Active Rehab (Group 2), Progressive Return to Activity (Group 1)
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Fort Liberty, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Phase 4 Interventional Results available

Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue

NCT03621761
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Telephone-based Cognitive Behavioral Therapy, Modafinil
Behavioral · Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Ann Arbor, Michigan • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Medication Management Among Individuals With Neurodevelopmental Disabilities

NCT03121651
View directory record Official record
Conditions
Spina Bifida, Cerebral Palsy
Interventions
RL-adaptive application
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 2, 2019 · Synced Oct 21, 2026, 8:14 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Long COVID-19 Intervention Using Digital Health & Technology

NCT05616806
View directory record Official record
Conditions
Long COVID, Distress Tolerance
Interventions
iENDURE
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Oct 21, 2026, 8:14 PM EDT
Not listed Not applicable Interventional

Usability of the Adapted Rower for People With Spinal Cord Injury

NCT05959837
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Adaptive Rowing Exercise
Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 21, 2026, 8:14 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)

NCT06799702
View directory record Official record
Conditions
HIV Pre-exposure Prophylaxis, HEPATITIS C (HCV), Opioid Use Disorder
Interventions
Telehealth Behavioral Intervention for promoting HIV and HCV care and MOUD among Persons who inject drugs (PWID)
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Colbert, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

Healthy Hearts Healthy Minds

NCT03373110
View directory record Official record
Conditions
Cardiovascular Diseases, Depression
Interventions
Online Mindfulness Based Cognitive Therapy, Online Cognitive Behavioral Therapy, Fitbit Alone
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
506 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Phase 2 Interventional

Adaptive Goal-Directed Adherence Tracking and Enhancement

NCT01349985
View directory record Official record
Conditions
Alcohol Abuse
Interventions
AGATE, SASED
Other
Lead sponsor
Talaria, Inc
Industry
Eligibility
21 Years to 55 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 13, 2014 · Synced Oct 21, 2026, 8:14 PM EDT
Not yet recruiting Phase 2 Interventional

Utilizing Standard of Care Induction Chemotherapy Followed by MR-LINAC Radiotherapy and Surgical Exploration to Improve Resectability Rates in Potentially Resectable Locally Advanced Pancreatic Cancer

NCT07871461
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Induction Chemotherapy - FOLFIRINOX, Induction Chemotherapy - Gemcitabine and Nab-Paclitaxel, MR-LINAC Guided Radiotherapy, Surgical Exploration and Resection
Drug · Radiation · Procedure
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Recruiting Not applicable Interventional

Telehealth Cognitive Behavioral Therapy for Youth at Risk for Psychosis

NCT05968560
View directory record Official record
Conditions
Clinical High Risk for Psychosis (CHR)
Interventions
CBT Skills Group for CHR Youth, Individual CBT sessions, CBT Skills Group for Families
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
14 Years to 25 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Active, not recruiting Not applicable Interventional

Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery

NCT04031716
View directory record Official record
Conditions
Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
Interventions
Meditation
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

GODART Pilot and Feasibility

NCT05344859
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Weekly Automated Health Coaching, Weekly Human Health Coaching, Adapted Reward Level, Fixed Gamified Reward Level
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 21, 2026, 8:14 PM EDT
Not listed Not applicable Interventional

Improving Treatments for Bulimia Nervosa: Innovation in Psychological Interventions for Regulating Eating

NCT02716831
View directory record Official record
Conditions
Bulimia Nervosa, Bulimia, Binge Eating, Purging (Eating Disorders), Eating Disorder
Interventions
Nutritional Counseling & Acceptance-based Therapy, Cognitive Behavioral Therapy for Eating Disorders
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2018 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional Results available

An Adaptive Intervention for Adolescents at Risk for Suicide: A Pilot SMART

NCT03838198
View directory record Official record
Conditions
Suicide, Self Harm
Interventions
MI-Enhanced Safety Plan at Hospitalization (1st Component), MI-Enhanced Text Boosters (2nd Component), MI-Enhanced Booster Call (3rd Component)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

TODAY! A Mobile App Study

NCT03534167
View directory record Official record
Conditions
Depression, Anxiety
Interventions
TODAY! App and Coaching
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
14 Years to 24 Years · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2023 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

NCT05282225
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
Interventions
MI- Safety Plan, Texts messages, Monitoring, Portal follow-up, Booster call
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Not yet recruiting Not applicable Interventional

Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design

NCT07721064
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Digital Insomnia Program, Digital Mental Health Program, Psychoeducation
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older · Female only
Enrollment
747 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Enrolling by invitation Not applicable Interventional

Comparing Two Moral Injury Treatments

NCT07710521
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 8:14 PM EDT
Completed Not applicable Interventional

Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors

NCT05364450
View directory record Official record
Conditions
Breast Neoplasm, Breast Cancer, Breast Carcinoma, Malignant Neoplasm of Breast, Cancer of Breast, Mammary Neoplasms, Human, Human Mammary Carcinoma, Malignant Tumor of Breast, Mammary Cancer, Mammary Carcinoma, Human, Anxiety, Fear
Interventions
Enhanced Usual Care, Acceptance Commitment Therapy, Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced Oct 21, 2026, 8:14 PM EDT