Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 3, 2026, 2:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 119 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Adductor canal block Clear all
Completed Not applicable Interventional Results available

Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

NCT03395990
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Active comparator: chloroprocaine, Sham comparator: saline
Procedure
Lead sponsor
Duke University
Other
Eligibility
56 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Oct 3, 2026, 2:10 PM EDT
Not listed Phase 4 Interventional

IPACK on Early Pain Scores After ACL Reconstruction

NCT05985629
View directory record Official record
Conditions
Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
Interventions
IPACK, PLACEBO
Drug
Lead sponsor
Loyola University
Other
Eligibility
16 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction

NCT02584452
View directory record Official record
Conditions
Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
Interventions
Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine, adductor canal nerve block, ropivacaine and dexamethasone, Propofol, Fentanyl
Drug · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
14 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Phase 4 Interventional

Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty

NCT06784882
View directory record Official record
Conditions
Acute Postoperative Pain, Surgery
Interventions
continuous peripheral nerve block with OnQ pump, single injection nerve block
Device · Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 17, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Withdrawn Not applicable Interventional

Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain

NCT06284109
View directory record Official record
Conditions
Postoperative Pain
Interventions
Cryoanalgesia, Sham Cryoanalgesia
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Withdrawn Phase 4 Interventional

Adductor Canal Catheter vs Local Infiltration of Analgesia for Total Knee Arthroplasty

NCT02603900
View directory record Official record
Conditions
Acute Pain, Regional Anesthesia Morbidity
Interventions
ropivacaine, bupivacaine, Sham Adductor Canal Catheter, Adductor Canal Catheter
Drug · Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
40 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Early Phase 1 Interventional

Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty

NCT02991404
View directory record Official record
Conditions
Total Knee Arthroplasty, Pain, Postoperative, Adductor Canal Block
Interventions
Multimodal Peripheral Nerve Block Injection, Single Shot Adductor Canal Block, Initial Bolus, Continuous infusion
Procedure · Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Analgesic Efficacy of Anterior Femoral, Genicular and Adductor Canal Nerve Block

NCT02548104
View directory record Official record
Conditions
Pain, Postoperative
Interventions
ACB, ACB + iPACK
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 90 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 19, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Results available

Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft:

NCT05286307
View directory record Official record
Conditions
Anterior Cruciate Ligament Rupture
Interventions
IPACK block
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Results available

Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty

NCT05139030
View directory record Official record
Conditions
Knee Osteoarthritis, Pain Management
Interventions
bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
6
States / cities
Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)

NCT02197273
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
Interventions
Liposomal bupivacaine, Standard of care analgesia
Drug
Lead sponsor
OhioHealth
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 3, 2026, 2:10 PM EDT
Withdrawn Not applicable Interventional

Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA

NCT04292392
View directory record Official record
Conditions
Knee Arthropathy
Interventions
preop ACB, followed by Intra-articular block during TKA surgery, preop ACB+IPACK block, preop ACB+IPACK block, followed by Intra-articular block during TKA surgery
Other
Lead sponsor
University of Louisville
Other
Eligibility
22 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Results available

Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

NCT03326999
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Rheumatism
Interventions
Obturator nerve regional block, Adductor canal regional block, Saline
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty

NCT03133481
View directory record Official record
Conditions
Arthropathy of Knee
Interventions
Adductor Canal Nerve Block, Femoral Nerve Block
Procedure · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 100 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service

NCT03747146
View directory record Official record
Conditions
Anesthesia
Interventions
Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 65 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Phase 2 Interventional

Yale Steroid Enhanced Versus Exparel Nerveblock TKA Part 2

NCT05736549
View directory record Official record
Conditions
Total Knee Replacement, Knee Arthroplasty
Interventions
Bupivacaine-Liposomal Bupivacaine, Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Perineural Steroids for Peripheral Nerve Blocks

NCT02462148
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Dexamethasone, Bupivacaine, Epinephrine, Saphenous Peripheral Nerve Block
Drug · Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Oct 3, 2026, 2:10 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees

NCT06590402
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction, Medial Patellofemoral Ligament Reconstruction
Interventions
Bupivacaine, Dexamethasone in Adductor Canal Block, Bupivacaine, Dexamethasone in Anterior Femoral Cutaneous Nerve Block
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
8 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl vs. Bupivacaine HCl Administered as Combined Sciatic and Saphenous Nerve Blocks for Postsurgical Analgesia in Subjects Undergoing Lower Extremity Surgeries

NCT04518462
View directory record Official record
Conditions
Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion, Midfoot Fusion, Hindfoot Fushion, Total Ankle Arthroplasty
Interventions
Exparel, Bupivacaine Hydrochloride
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
5
States / cities
Phoenix, Arizona • Pasadena, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement

NCT01805661
View directory record Official record
Conditions
Pain, Osteoarthritis
Interventions
Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Results available

Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction

NCT03704376
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine, High-frequency linear ultrasound transducer
Drug · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
16 Years to 30 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 21, 2021 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Adductor Canal Blocks With Bupivacaine and Magnesium After Same-day Discharge Total Knee Arthroplasty Improve Post-operative Pain Relief and Decrease Opioid Consumption: a Prospective Randomized Controlled Trial

NCT05004636
View directory record Official record
Conditions
Post-operative Pain, Acute
Interventions
Adding Magnesium as an adjuvant to the adductor canal Block (ACB) for same-day discharge total knee arthroplasty
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 100 Years
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pontiac, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 13, 2021 · Synced Oct 3, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA

NCT02218814
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Nerve Block
Interventions
Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
Procedure
Lead sponsor
George Macrinici
Other
Eligibility
40 Years to 80 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Oct 3, 2026, 2:10 PM EDT
Terminated Phase 4 Interventional Results available

Liposomal Bupivacaine Versus Standard Bupivacaine in the Adductor Canal for Total Knee Arthroplasty

NCT03182933
View directory record Official record
Conditions
Pain
Interventions
Peripheral Nerve Blockade, 10 meter walk test on post-operative day 1, In person and over the phone questionnaire, Force transduction of quadriceps strength
Drug · Behavioral · Other + 1 more
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 80 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 3, 2026, 2:10 PM EDT