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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Advance Directives Clear all
Completed Not applicable Interventional

Reducing Disparities in the Quality of Advance Care Planning for Older Adults

NCT03516994
View directory record Official record
Conditions
Metastatic Cancer, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Parkinson Disease, Interstitial Lung Disease, Amyotrophic Lateral Sclerosis, End Stage Liver Disease, End Stage Renal Disease, Diabetes Complications
Interventions
Respecting Choices First Steps, Five Wishes Form
Behavioral
Lead sponsor
Duke University
Other
Eligibility
65 Years and older
Enrollment
790 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Birmingham, Alabama • Atlanta, Georgia • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 15, 2024 · Synced Sep 19, 2026, 8:08 PM EDT
Recruiting Not applicable Interventional

I CAN DO Surgical ACP

NCT06090552
View directory record Official record
Conditions
Surgical Advanced Care Planning
Interventions
Letter, AD, PREPARE website, reminders, healthcare navigator
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Irvine, California • San Francisco, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Results available

An Effectiveness-Implementation Trial of SPIRIT in ESRD

NCT03138564
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
SPIRIT, Comparison Condition
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
852 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
39
States / cities
Atlanta, Georgia • Decatur, Georgia • North Decatur, Georgia + 29 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Results available

SPIRIT for Persons With Dementia and Complex Multimorbidity

NCT04108000
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
SPIRIT-Dementia, Usual Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
4
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Intervention to Improve Expression of End of Life Preferences for Homeless Persons

NCT00546884
View directory record Official record
Conditions
Healthy
Interventions
MI condition, GI
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 12, 2017 · Synced Sep 19, 2026, 8:08 PM EDT
Active, not recruiting Not applicable Interventional

Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers

NCT05596760
View directory record Official record
Conditions
Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease, Huntington Disease, Lewy Body Disease, Creutzfeldt-Jakob Syndrome, Frontotemporal Lobar Degeneration, Cognitive Dysfunction, Cognitive Aging, Chronic Disease, Palliative Care, Patient Care, Health Care Quality, Access, and Evaluation, Patient Care, Health Communication, Patient Care Planning, Quality of Life
Interventions
Jumpstart Guide
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed No phase listed Observational

Cardiopulmonary Resuscitation (CPR) Video to Enhance Advance Care Planning in Advanced Upper Gastrointestinal Cancer Patients

NCT01105806
View directory record Official record
Conditions
Pancreas and Hepatobiliary Cancer Patients
Interventions
(CPR) video and questionnaires, cardiopulmonary resuscitation (CPR) narrative script and questionnaires
Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Results available

Aligning Patient Preferences: a Role Offering Alzheimer's Patients, Caregivers, and Healthcare Providers Education and Support

NCT03323502
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
APPROACHES ACP Specialist Program, Standard of care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
47,396 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
Warsaw, Indiana • Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Sep 19, 2026, 8:08 PM EDT
Recruiting Not applicable Interventional

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

NCT05297734
View directory record Official record
Conditions
End of Life, Cancer
Interventions
Receive technology-based supportive cancer care, Receive redesigned team-based supportive cancer care
Other · Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
2,996 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
17
States / cities
Birmingham, Alabama • Mobile, Alabama • Duarte, California + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Patient Perception of Video Advance Care Planning

NCT02692950
View directory record Official record
Conditions
Advanced Directive Planning
Interventions
Honor My Decisions Advance Care Planning Video, Post-video questionnaire
Other · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Results available

Evaluating Evidence-Based Quality Improvement of Comprehensive Women's Health Care Implementation in Low-Performing VAs

NCT03238417
View directory record Official record
Conditions
Comprehensive Care
Interventions
Evidence-Based Quality Improvement
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
25
States / cities
Montgomery, Alabama • Prescott, Arizona • Sacramento, California + 22 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Advance Care Planning for Older Latinos With Chronic Illness

NCT06081660
View directory record Official record
Conditions
Patient Engagement, End of Life, Chronic Disease, Communication
Interventions
ACP-I Plan
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
50 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Sep 19, 2026, 8:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Telephone-Based Coaching Sessions (TAC) to Improve Advance Care Planning Participation in Advanced Cancer Patients and Their Support Person

NCT07141407
View directory record Official record
Conditions
Advanced Malignant Solid Neoplasm, Hematopoietic and Lymphatic System Neoplasm
Interventions
Supportive Care, Telephone-Based Intervention, Survey Administration, Educational Intervention
Other · Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Everett, Washington • Mount Vernon, Washington • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Acceptability of Palliative Care in Parkinson Disease Care

NCT03697434
View directory record Official record
Conditions
Parkinson Disease
Interventions
Palliative Care referral
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 8, 2019 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Palliative Care Coaching for Families With Rare Advanced Lung Diseases

NCT03813667
View directory record Official record
Conditions
Lung Diseases, Rare Non-Neoplastic Disorder
Interventions
Intervention FamPALcare
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 20, 2019 · Synced Sep 19, 2026, 8:08 PM EDT
Enrolling by invitation Not applicable Interventional

Emergency Care Action Plans for Infants with Medical Complexity

NCT06444282
View directory record Official record
Conditions
Children with Medical Complexity, Child, Only, Infant Morbidity, Infant Conditions, Utilization, Health Care, Emergencies, Chronic Condition
Interventions
Emergency Care Action Plan
Other
Lead sponsor
University of Vermont
Other
Eligibility
Up to 6 Months
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Representational Intervention to Promote Preparation for End-of-life Decision Making

NCT01259011
View directory record Official record
Conditions
End Stage Renal Disease
Interventions
the SPIRIT intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Stanford Letter or Traditional Advance Directive in Advance Care Planning in Patients Undergoing Bone Marrow Transplant

NCT03028961
View directory record Official record
Conditions
Advance Directives, Bone Marrow Transplant
Interventions
Stanford Letter, Interview, Questionnaire Administration, CA Advance Health Care Directive Form
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 100 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 13, 2022 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of an Easy to Read Advance Directive Versus a Standard Advance Directive

NCT00328055
View directory record Official record
Conditions
Aging
Interventions
AD-Easy (Advance Directive-Easy), AD-Standard (Advance Directive-Standard)
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 24, 2011 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Comparison of a Web-based Advance Directive to a Standard Advance Directive

NCT03676426
View directory record Official record
Conditions
GI Cancer, Thoracic Cancer
Interventions
Web platform for advance care planning/advance directive, Standard advance directive
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 6, 2020 · Synced Sep 19, 2026, 8:08 PM EDT
Recruiting Not applicable Interventional

Resilience-Building for Advance Care Planning

NCT07428278
View directory record Official record
Conditions
Advanced Cancer, End of Life
Interventions
ROCKS, Usual Care
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 80 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers

NCT04994782
View directory record Official record
Conditions
Implantable Defibrillator User, Terminal Illness
Interventions
GAME-EOL
Behavioral
Lead sponsor
Debra Moser
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Sep 19, 2026, 8:08 PM EDT
Completed Not applicable Interventional

Advance Care Planning Coaching for Patients With Chronic Kidney Disease

NCT03506087
View directory record Official record
Conditions
Chronic Kidney Diseases
Interventions
Advance care planning coaching session., Printed advance care planning materials
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
55 Years and older
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Springfield, Massachusetts • Asheville, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2020 · Synced Sep 19, 2026, 8:08 PM EDT
Not yet recruiting Not applicable Interventional

A Multi-Site Hybrid Type I Effectiveness-Implementation Randomized Trial of an Emergency Care Action Plan for Infants With Medical Complexity

NCT06993129
View directory record Official record
Conditions
Chronic Disease Management, Infants Health, Emergency, Utilization, Health Care, Caregiver Stress
Interventions
Emergency Care Action Plan
Other
Lead sponsor
University of Vermont
Other
Eligibility
0 Months to 6 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
4
States / cities
Aurora, Colorado • Cincinnati, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Sep 19, 2026, 8:08 PM EDT