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ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:53 AM EDT

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Showing 25–43 of 43 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Agent DCB Clear all
Completed Phase 4 Interventional Results available

Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging

NCT02807779
View directory record Official record
Conditions
Peripheral Artery Disease, Vascular Disease, Critical Limb Ischemia
Interventions
Dexamethasone infusion, Drug coated balloon, Plain balloon angioplasty
Drug · Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
35 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
2
States / cities
San Francisco, California • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Active, not recruiting No phase listed Observational

OPtilume™ BPH Catheter SystEm for Treatment of Men eXperiencing Symptomatic BPH

NCT06560476
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Data collection
Other
Lead sponsor
Urotronic Inc.
Industry
Eligibility
Male only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
8
States / cities
Tampa, Florida • Kearney, Nebraska • Omaha, Nebraska + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Terminated Not applicable Interventional

Prospective Study for the Treatment of Atherosclerotic Lesions in the Superficial Femoral And/or Popliteal Arteries Using the FLEX Scoring Catheter Plus DCB

NCT03676842
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
FLEX Dynamic Scoring Catheter with IN.PACT Admiral DCB
Combination Product
Lead sponsor
VentureMed Group Inc.
Industry
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Safety and Effectiveness of the Optilume® BPH Catheter System in a Post-Market Study

NCT06312722
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Optilume® BPH Catheter System
Device
Lead sponsor
Urotronic Inc.
Industry
Eligibility
50 Years and older · Male only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
7
States / cities
Little Rock, Arkansas • Tampa, Florida • Shreveport, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Active, not recruiting Phase 3 Interventional Results available

A Clinical Trial to Assess the Agent Paclitaxel Coated PTCA Balloon Catheter for the Treatment of Subjects With In-Stent Restenosis (ISR)

NCT04647253
View directory record Official record
Conditions
In-Stent Restenosis
Interventions
AGENT DCB, PTCA balloon catheter
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
40
States / cities
Birmingham, Alabama • Tucson, Arizona • La Jolla, California + 33 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Paclitaxel in Patients With CLI and Femoropopliteal Occlusive Disease Treated With DCB Angioplasty

NCT02758847
View directory record Official record
Conditions
Ischemia
Interventions
Angiogram, Medtronic DCB (paclitaxel)/stent, Angiogram, Bard DCB (paclitaxel)/stent
Device
Lead sponsor
Rabih A. Chaer
Other
Eligibility
40 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

NCT06182397
View directory record Official record
Conditions
Arterial Disease of Legs, Below-the-knee Obstruction, PAD - Peripheral Arterial Disease
Interventions
MagicTouch PTA Sirolimus drug coated balloon, Placebo balloon angioplasty
Device
Lead sponsor
Concept Medical Inc.
Industry
Eligibility
21 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
29
States / cities
Scottsdale, Arizona • Los Angeles, California • Clearwater, Florida + 22 more
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Active, not recruiting Not applicable Interventional Results available

Optilume™ BPH Catheter System in Men With Symptomatic BPH

NCT04131907
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Optilume BPH Catheter System, Optilume Sham Device
Device
Lead sponsor
Urotronic Inc.
Industry
Eligibility
50 Years to 80 Years · Male only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
19
States / cities
Little Rock, Arkansas • Golden, Colorado • Daytona Beach, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Suspended Not applicable Interventional

Stellarex DCB Versus Standard Balloon Angioplasty for Treatment of Below-The-Knee (BTK) Arteries

NCT03175744
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Stellarex DCB, PTA Catheter
Device
Lead sponsor
Spectranetics Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
9
States / cities
Orange, California • Bradenton, Florida • Houma, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2023 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional

Virtue® SAB in the Treatment of Coronary ISR Trial

NCT07045194
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Virtue Sirolimus AngioInfusion Balloon, AGENT™ Paclitaxel Drug-Coated Balloon
Device
Lead sponsor
Orchestra BioMed, Inc
Industry
Eligibility
18 Years and older
Enrollment
740 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
22
States / cities
Phoenix, Arizona • Gainesville, Florida • Hollywood, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting Phase 3 Interventional

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

NCT05561127
View directory record Official record
Conditions
Bowel; Stricture
Interventions
GIE Medical ProTractX3 TTS DCB, Control
Combination Product · Other
Lead sponsor
GIE Medical
Industry
Eligibility
22 Years and older
Enrollment
171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
32
States / cities
Scottsdale, Arizona • Irvine, California • Lancaster, California + 25 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 29, 2026, 4:53 AM EDT
Recruiting No phase listed Observational

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

NCT07559903
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
17
States / cities
Phoenix, Arizona • Fort Lauderdale, Florida • Atlanta, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Directional Versus Orbital Atherectomy Plaque Modification and Luminal Area Assessment of the Femoro-popliteal Artery Via Intravascular Ultrasound

NCT03495453
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Percutaneous Revascularization of the Femoropopliteal Arteries using a DAS, Percutaneous Revascularization of the Femoropopliteal Arteries using a OAS device
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

LEVANT 2 Safety Registry

NCT01790243
View directory record Official record
Conditions
Peripheral Artery Disease, Femoropopliteal Artery Occlusion, Femoropopliteal Stenosis
Interventions
Lutonix Drug Coated Balloon, Standard PTA Balloon
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
1,189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
8
States / cities
Fremont, California • Wyoming, Michigan • Jackson, Mississippi + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Real-World Registry Assessing the Clinical Use of the Lutonix 035 Drug Coated Balloon Catheter

NCT02424383
View directory record Official record
Conditions
Peripheral Arterial Disease, Peripheral Vascular Diseases, Arterial Occlusive Diseases
Interventions
PTA (Lutonix® 035 DCB Catheter)
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
21 Years and older
Enrollment
1,005 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
73
States / cities
Alexander City, Alabama • Chandler, Arizona • Phoenix, Arizona + 63 more
Source: ClinicalTrials.gov public record
Updated May 22, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Completed No phase listed Observational Results available

TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions

NCT03306199
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Laser Atherectomy
Device
Lead sponsor
Spectranetics Corporation
Industry
Eligibility
Not listed
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Houma, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 29, 2026, 4:53 AM EDT
Active, not recruiting Not applicable Interventional

SELUTION 4 De Novo Small Vessel IDE Trial

NCT05946629
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
PCI with SELUTION SLR DCB, PCI with FDA approved "-limus" DES
Device
Lead sponsor
M.A. Med Alliance S.A.
Industry
Eligibility
18 Years and older
Enrollment
960 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
65
States / cities
Jonesboro, Arkansas • Chula Vista, California • Los Angeles, California + 54 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

LEVANT 2 Continuation Registry of the Lutonix® Drug Coated Balloon (DCB)

NCT01628159
View directory record Official record
Conditions
Peripheral Artery Disease
Interventions
Lutonix Drug Coated Balloon
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years and older
Enrollment
657 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
39
States / cities
Los Angeles, California • Oceanside, California • Orange, California + 32 more
Source: ClinicalTrials.gov public record
Updated Apr 10, 2020 · Synced Oct 29, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)

NCT02923193
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Shockwave Lithoplasty® Peripheral Lithoplasty System, Medtronic IN.PACT (DCB)
Device · Drug
Lead sponsor
Shockwave Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
40
States / cities
Little Rock, Arkansas • Palo Alto, California • Aurora, Colorado + 33 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2023 · Synced Oct 29, 2026, 4:53 AM EDT