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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
Conditions
Cardiovascular Diseases, Blood Pressure, Glycated Hemoglobin (HbA1c), Cholesterol, Cholesterol, HDL, Cholesterol, LDL, Indoor Air Quality, Particulate Matter, Health Behavior
Interventions
Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control
Behavioral · Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years to 79 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Missoula, Montana
Recruiting Not applicable Interventional Accepts healthy volunteers

HEPA, PM2.5, and Cardiometabolic Health

NCT05718245
Conditions
Air Pollution, Cardiometabolic Health
Interventions
HEPA filter, Sham filter
Device
Lead sponsor
University of Southern California
Other
Eligibility
65 Years to 84 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Conditions
COPD, Chronic Obstructive Pulmonary Disease
Interventions
Active HEPA Air Cleaner, Motivational interviewing, Sham Air Cleaner
Device · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
40 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Traffic Pollution Exposure Improves Blood Pressure

NCT04029129
Conditions
Air Pollution
Interventions
Air filtration and building envelop modifications
Other
Lead sponsor
UConn Health
Other
Eligibility
40 Years to 75 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
HEPA portable air filter, Sham Control/Active Comparator
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
40 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Fasting
Interventions
a breath analysis using the Aeonose, Aeonose
Other · Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Coronary Heart Disease, Cardiovascular Diseases, Environmental Exposure
Interventions
AIRWISE
Other
Lead sponsor
University of Montana
Other
Eligibility
55 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Missoula, Montana
Completed Not applicable Interventional Accepts healthy volunteers Results available

School Inner-City Asthma Intervention Study (SICAS-2)

NCT02291302
Conditions
Asthma
Interventions
integrated pest management, air purifier, No intervention (control)
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
4 Years to 15 Years
Enrollment
236 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Asthma
Interventions
NO2 Scrubber, HEPA filter, Control
Other
Lead sponsor
Yale University
Other
Eligibility
5 Years to 11 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Not listed Not applicable Interventional Accepts healthy volunteers

ASPIRE Health Tulare County

NCT05944770
Conditions
Respiratory Tract Diseases, Cardiovascular Diseases
Interventions
DIY portable air cleaner with a highly effective filter, DIY portable air cleaner with sham filtration
Other
Lead sponsor
Environmental Protection Agency (EPA)
Federal
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fresno, California
Conditions
COPD, Eosinophilia
Interventions
Air purifier, Sham air purifier
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
40 Years and older
Enrollment
178 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Asthma
Interventions
Active Air Purifier, Placebo Air Purifier
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
8 Years to 17 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Patient Satisfaction, Pulmonary Rehabilitation
Interventions
TrachPhone Heat Moisture Exchange, Trach Collar
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Tampa, Florida
Recruiting Not applicable Interventional

Project 4: ACHIEVE PATHFINDER

NCT06070428
Conditions
Heart Failure
Interventions
PAC provision at hospital discharge, Control non-intervention; PAC without filter
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Conditions
Cardiovascular Risk Factor, Blood Pressure
Interventions
HEPA Air Filtration, Sham HEPA Air Filtration
Other
Lead sponsor
UConn Health
Other
Eligibility
30 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Air Pollution, Indoor
Interventions
Air purifier
Device
Lead sponsor
Alaska Native Tribal Health Consortium
Other
Eligibility
Up to 5 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethel, Alaska
Conditions
Asthma
Interventions
woodstove, inactive air filter, Active air filter
Other
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
10 Years to 17 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Missoula, Montana
Completed Not applicable Interventional Results available

Cleaner Air for Better Cardiac Biomarkers

NCT05379400
Conditions
Cardiovascular Diseases
Interventions
Portable air cleaner (PAC), Sham Portable air cleaner (PAC)
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Commute Traffic on Vascular Function

NCT05454930
Conditions
Cardiovascular Diseases
Interventions
Filtered Air
Other
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 49 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Pediatric Asthma
Interventions
Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA)
Device
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Results available

Residential Cleaning of Indoor Air to Protect COPD Patients

NCT03750292
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
HEPAirX air filter, control air filter
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wood Stove Interventions and Child Respiratory Health

NCT02240134
Conditions
Lower Tract Respiratory Infection
Interventions
Education Intervention (Tx1), Air Filtration Unit Treatment (Tx2), Placebo Intervention (Tx3)
Behavioral · Device
Lead sponsor
University of Montana
Other
Eligibility
Up to 5 Years
Enrollment
523 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Missoula, Montana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reducing Particulate Matter-associated Cardiovascular Health Effects for Seniors

NCT04103346
Conditions
Cardiometabolic Health
Interventions
air filtration with air purifier with hepa filter, sham
Other
Lead sponsor
University of Michigan
Other
Eligibility
60 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Terminated Not applicable Interventional Results available

Pediatric Helmet CPAP Pilot Study

NCT04764929
Conditions
Bronchiolitis, Viral, Pneumonia, Viral, Pneumonia, Bacterial
Interventions
Helmet CPAP
Device
Lead sponsor
Columbia University
Other
Eligibility
1 Month to 5 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York