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Showing 1–24 of 83 matching trials from the live ClinicalTrials.gov search.
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Conditions
PostTraumatic Stress Disorder
Interventions
Ropivacaine, Sham treatment
Drug
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Bragg, North Carolina
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

The PAIN (Pelvic Area Injection for Numbness) Study

NCT05972681
Conditions
Vaginal Laceration During Delivery
Interventions
Bupivacaine, Epinephrine, Sham normal saline arm
Drug · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
The Bronx, New York
Completed Not applicable Interventional Results available

Clinical Intervention in Alcohol Use Disorder

NCT02168400
Conditions
Alcohol Use Disorder, Eligible to go Into the MRI Scanner, Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Interventions
Transcranial Direct Current Stimulation (tDCS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Substance Use Disorders, Opioid Use Disorder, Alcohol Use Disorder, Cocaine Use Disorder, Methamphetamine-dependence
Interventions
EDITOR (CBOT with olfactory stimulants, OFC tasks & remote monitoring of treatment compliance), CBOT with olfactory stimulants & OFC tasks, CBOT Sham
Combination Product
Lead sponsor
Evon Medics LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Rockville, Maryland
Completed Not applicable Interventional Results available

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

NCT04223154
Conditions
Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
Interventions
Real iTBS to the dlPFC, Sham iTBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
Interventions
Real time fMRI neurofeedback
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
21 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alcohol Use Disorder
Interventions
active rTMS, Inpatient admission, sham rTMS
Device · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
22 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Alcohol Use Disorder
Interventions
Realtime fMRI Neurofeedback - Active, TMS - Active, Realtime fMRI Neurofeedback - Yoked Sham, TMS - Sham
Behavioral · Device
Lead sponsor
Auburn University
Other
Eligibility
19 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn, Alabama
Recruiting Phase 2 Interventional Accepts healthy volunteers

Role of Sympathetic Overactivity and Angiotensin II in PTSD and CV

NCT02560805
Conditions
Stress Disorders, Post-Traumatic
Interventions
Microneurography, Combat virtual reality video clip, Handgrip Exercise, Cold Pressor Test (CPT), Sodium Nitroprusside (SNP), Phenylephrine, Losartan, Atenolol, Transcutaneous Vagal Nerve Stimulation (tVNS), Sham Transcutaneous Vagal Nerve Stimulation (tVNS)
Procedure · Behavioral · Drug + 1 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Decatur, Georgia
Conditions
Cervical Spine Fusion
Interventions
Bupivacaine Hcl 0.25% Inj, Normal saline
Drug · Other
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years to 80 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Autonomic Failure, Orthostatic Hypotension
Interventions
Atomoxetine, Acarbose, Pyridostigmine Bromide, Yohimbine, Midodrine HCl, placebo, Modafinil, Octreotide, water intake, Diphenhydramine Hydrochloride, Ranitidine HCL, Tranylcypromine, Ergotamine/ Caffeine, Celecoxib, Pseudoephedrine, Methylphenidate, Indomethacin, Ibuprofen, Oxymetazoline 0.05% nasal solution, Bovril, Acetazolamide, Rivastigmine tartrate, Carbidopa/levodopa, Inflatable abdominal binder, inflatable abdominal binder (sham)
Drug · Other · Dietary Supplement + 1 more
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 85 Years
Enrollment
389 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Alcohol Use Disorder
Interventions
Contingency management
Behavioral
Lead sponsor
Mikhail N Koffarnus
Other
Eligibility
18 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Lexington, Kentucky • Roanoke, Virginia
Conditions
Alcohol Use Disorder, Depressive Disorder, Cigarette Smoking
Interventions
Intermittent theta burst transcranial magnetic stimulation
Device
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Palo Alto, California • Stanford, California
Completed Not applicable Interventional Results available

Theta Burst Stimulation for Alcohol Use Disorder

NCT06060496
Conditions
Alcohol Use Disorder
Interventions
Active cTBS, Sham cTBS
Device
Lead sponsor
Gopalkumar Rakesh
Other
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Alcohol Withdrawal
Interventions
Transcutaneous Auricular Neurostimulation (tAN)
Device
Lead sponsor
Erin Takemoto
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Wernersville, Pennsylvania
Conditions
Alcohol Use Disorder
Interventions
Approach Avoidance Training, Sham Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Conditions
Alcoholism
Interventions
Transcranial Magnetic Stimulation (rTMS), Sham (SS)
Device
Lead sponsor
Nassima Ait-Daoud Tiouririne
Other
Eligibility
22 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Alcohol Use Disorder, Mild-Moderate Traumatic Brain Injury
Interventions
Personalized VR Alcohol Approach Bias Modification (ApBM) Condition, Sham Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
San Francisco, California
Conditions
Pain Management
Interventions
Bupivacaine/Epinephrine, Saline
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Glaucoma, Open-Angle, Ocular Hypertension
Interventions
Bimatoprost SR, Sham: Applicator Without Needle, Active Comparator: Timolol 0.5%, Timolol Vehicle (placebo)
Drug · Other
Lead sponsor
Allergan
Industry
Eligibility
18 Years and older
Enrollment
528 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
51
States / cities
Dothan, Alabama • Chandler, Arizona • Fayetteville, Arkansas + 47 more
Conditions
Breast Cancer, Neuropathy
Interventions
Electro-acupuncture, Sham acupuncture
Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
New York, New York
Conditions
Gastroesophageal Reflux
Interventions
Cognitive Behavioral Therapy, Sham-SOC Lifestyle Coaching
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • St Louis, Missouri
Conditions
Alcoholism, Cocaine Addiction, Drug Addiction
Interventions
Real continuous Theta Burst Stimulation, Sham continuous Theta Burst Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
25 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Phase 3 Interventional Accepts healthy volunteers

Posterior Tibial Nerve Stimulation vs. Sham

NCT00534521
Conditions
Overactive Bladder
Interventions
Posterior Tibial Nerve Device, Sham
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Royal Oak, Michigan