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ClinicalTrials.gov public records Last synced Sep 27, 2026, 10:43 AM EDT

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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Allograft/Xenograft Clear all
Enrolling by invitation Not applicable Interventional

The Effectiveness of Carbonate Apatite Bone Graft for Alveolar Ridge Preservation

NCT07020650
View directory record Official record
Conditions
Healing Wound
Interventions
Socket preservation
Device
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 80 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft

NCT05400213
View directory record Official record
Conditions
Dental Extraction, Wound Heal
Interventions
Vallos (DCP), Vallomix (DCF), Vallos-F (DPX), Vallomix-F (DFX)
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

An RCT Comparing Xenograft and Allograft for Ridge Preservation

NCT02330523
View directory record Official record
Conditions
Tooth Loss
Interventions
allograft + x-link collagen membrane, xenograft + non-x-link collagen
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

CopiOs® Pericardium Membrane for Localized Alveolar Ridge Augmentation

NCT00889265
View directory record Official record
Conditions
Alveolar Ridge Defect
Interventions
CopiOs Pericardium Membrane
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
4
States / cities
Aurora, Colorado • Indianapolis, Indiana • Houston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Sep 27, 2026, 10:43 AM EDT
Recruiting No phase listed Observational

AlloMend Acellular Dermal Matrix Allograft in Pre-Pectoral Breast Reconstruction

NCT06512259
View directory record Official record
Conditions
Pre-Pectoral Breast Reconstruction Following Single or Double Mastectomy
Interventions
AlloMend® Acellular Dermal Matrix allograft
Other
Lead sponsor
AlloSource
Industry
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 10:43 AM EDT
Not yet recruiting No phase listed Observational

Outcomes of Different Bone Graft Combinations for Maxillary Sinus Augmentation Procedure

NCT07512011
View directory record Official record
Conditions
Bone Grafting, Sinus Lifting
Interventions
Bone grafting on both sides
Device
Lead sponsor
Ohio State University
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 27, 2026, 10:43 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Root Coverage Comparing an Allograft to a Bovine Xenograft

NCT02810067
View directory record Official record
Conditions
Gingival Recession
Interventions
Tunnel + AlloDerm, Tunnel + Novomatrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years to 120 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation

NCT06173791
View directory record Official record
Conditions
Bone Loss in Jaw
Interventions
DFDBA fibers, DFDBA particles, DBBM
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 89 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Sep 27, 2026, 10:43 AM EDT
Completed No phase listed Observational

Outcomes of the Evans Calcaneal Lengthening Based on Bone Grafting Material

NCT02075853
View directory record Official record
Conditions
Cerebral Palsy, Pes Planus
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
4 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft

NCT01431131
View directory record Official record
Conditions
Clinical Efficacy
Interventions
Intrasocket graft, Intrasocket plus facial overlay graft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Volumetric Changes and Graft Stability in Lateral Window Sinus Augmentation: A Prospective Clinical Trial

NCT03639077
View directory record Official record
Conditions
Lateral Window Sinus Augmentation
Interventions
Allograft bone alone, Allograft and xenograft mixture
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 27, 2026, 10:43 AM EDT
Withdrawn Phase 1 Interventional

Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease

NCT05340426
View directory record Official record
Conditions
Kidney Failure, Chronic
Interventions
UKidney
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing a PTFE Nonresorbable Membrane to a Collagen Membrane

NCT01900964
View directory record Official record
Conditions
Clinical Efficacy
Interventions
PTFE membrane, Collagen membrane
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Louisvile, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 27, 2026, 10:43 AM EDT
Not listed Phase 2 Interventional

Safety and Efficacy Study of Autologous Engineered Skin Substitute to Treat Partial- and Full-Thickness Burn Wounds

NCT01655407
View directory record Official record
Conditions
Thermal Injury, Deep Partial-Thickness Burn, Full-Thickness Burn
Interventions
Autologous Engineered Skin Substitute, Split-Thickness Autograft (AG)
Drug
Lead sponsor
Amarantus BioScience Holdings, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Pheonix, Arizona • Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Sep 27, 2026, 10:43 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Release Kinetics in PRF Versus GEM21S With and Without Bone Substitutes: An In Vitro Analysis

NCT04964466
View directory record Official record
Conditions
Bone Loss
Interventions
Amount of PDGF-BB in PRF preparation vs. GEM21, Amount of PDGF-BB available in PRF + bone substitutes vs. rhPDGF-BB+ bone substitutes following preparation, Release kinetics of PDGF-BB in PRF + bone substitutes vs. rhPDGF-BB + bone substitutes, Release kinetics of PDGF-BB in rhPDGF-BB + PRF + bone substitutes
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft

NCT02139748
View directory record Official record
Conditions
Dental Implants
Interventions
Dental Implant & ADM, Dental Implant & ADM & bone xenograft
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 27, 2026, 10:43 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft

NCT04550689
View directory record Official record
Conditions
Tooth Loss
Interventions
Bone graft
Device
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing 2 Membranes

NCT01905280
View directory record Official record
Conditions
Alveolar Ridge Deficiency
Interventions
Non-resorbable membrane, Acellular dermal matrix
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Prospective Clinical Study

NCT06342973
View directory record Official record
Conditions
Alveolar Ridge Deficiency
Interventions
Xenograft and allograft
Device
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 10:43 AM EDT
Active, not recruiting No phase listed Observational

Retrospective Study of AlloMend Acellular Dermal Matrix (ADM) Allograft and Pre-Pectoral Breast Reconstruction

NCT06853964
View directory record Official record
Conditions
Pre-Pectoral Breast Reconstruction Following Mastectomy
Interventions
AlloMend® Acellular Dermal Matrix allograft
Other
Lead sponsor
AlloSource
Industry
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Reno, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Sep 27, 2026, 10:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix

NCT07613047
View directory record Official record
Conditions
Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
Interventions
Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 27, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant

NCT06722482
View directory record Official record
Conditions
Ridge Preservation, Allografts, Extraction, Tooth, Xenograft
Interventions
FDBA, CEBX
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ridge Preservation Comparing the Healing With or Without a Barrier Membrane

NCT02798887
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Ridge preservation
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 27, 2026, 10:43 AM EDT
Completed Phase 4 Interventional

Ridge Preservation Comparing a Polylactic Acid Membrane vs. an Acellular Dermal Matrix Membrane

NCT02152215
View directory record Official record
Conditions
Ridge Preservation
Interventions
Acellular dermal matrix membrane, Polylactic acid membrane
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 7, 2016 · Synced Sep 27, 2026, 10:43 AM EDT