- Conditions
- Acute Mountain Sickness and Fatigue
- Interventions
- Aminophylline 400 mg, Ambrisentan 5 mg, Placebo
- Drug · Other
- Lead sponsor
- Robert J Noveck, M.D.
- Other
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 92 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2014
- U.S. locations
- 2
- States / cities
- Durham, North Carolina
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- Conditions
- High Altitude Pulmonary Hypertension
- Interventions
- Aminophylline, Ambrisentan, Aminophylline plus ambrisentan
- Drug
- Lead sponsor
- Thies Schroeder
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Hypertension, Pulmonary
- Interventions
- Ambrisentan - low dose, Ambrisentan - high dose
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 8 Years to 18 Years
- Enrollment
- 41 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 4
- States / cities
- Aurora, Colorado • Boston, Massachusetts • Ann Arbor, Michigan + 1 more