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Showing 1–24 of 462 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: American Diet Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Obesity Risk in African American Women is Determined by a Diet-by-phenotype Interaction

NCT03499509
View directory record Official record
Conditions
Diet Modification
Interventions
Low Glycemic Diet, High Glycemic Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 65 Years · Female only
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 17, 2025 · Synced Sep 6, 2026, 1:59 AM EDT
Completed No phase listed Observational

A Prospective Study of Diet and Cancer in Members of the American Association of Retired Persons

NCT00340015
View directory record Official record
Conditions
Death, Cancer
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
50 Years to 71 Years
Enrollment
566,401 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2022 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Effect of High Fat and High Glycemic Diets

NCT01494935
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High Glycemic Diet, Control diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional

A Church Based Intervention to Improve Diabetes Care

NCT00311324
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Special Intervention, Delayed Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
20 Years to 99 Years
Enrollment
201 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 19, 2023 · Synced Sep 6, 2026, 1:59 AM EDT
Terminated Not applicable Interventional

Reducing Insulin, Growth Hormones, and Tumors

NCT03785808
View directory record Official record
Conditions
Diet Modification, Lung Cancer
Interventions
Special Diet Therapy (low-carb), Special Diet Therapy (low-fat), Special Diet Therapy (USDA control)
Behavioral
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 11, 2019 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

The DINE Study-Diet Intervention to Negate Diabetes Study (Improving Weight Loss Outcomes for African Americans)

NCT00599040
View directory record Official record
Conditions
Diabetes, Hypertension, Insulin Resistance
Interventions
The DASH diet with weight loss, The DASH diet without weight loss, Dairy diet
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 6, 2026, 1:59 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Prostate Cancer Screening and Dietary Heterocyclic Amines in African American Men

NCT00354497
View directory record Official record
Conditions
Prostate Cancer
Interventions
physiologic testing, study of socioeconomic and demographic variables, evaluation of cancer risk factors, mutation carrier screening, study of high risk factors
Other · Procedure
Lead sponsor
Lawrence Livermore National Laboratory at University of California
Other
Eligibility
50 Years to 70 Years · Male only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2002
U.S. locations
2
States / cities
Livermore, California • Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2013 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

NCT04990817
View directory record Official record
Conditions
Elevated Triglycerides, Hypertriglyceridemia
Interventions
Average American Diet With SoFAS Replaced With Avocado, Average American Diet
Other
Lead sponsor
Midwest Center for Metabolic and Cardiovascular Research
Other
Eligibility
21 Years to 74 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chicago, Illinois • Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Loss and Cognitive Function in Adults

NCT03685305
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Hypocaloric diet with hunger reduction strategy, Hypocaloric diet without hunger reduction strategy
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
50 Years to 75 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Sep 6, 2026, 1:59 AM EDT
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Effects of a Supplement Derived From Palm Oil on Cholesterol Levels and Chinese Red Yeast Rice in the Blood

NCT02142569
View directory record Official record
Conditions
Cholesterol Lowering
Interventions
Sugar Pill, Chinese Red Yeast Rice (CRYR), CRYR + TRF, Tocotrienol-enriched Fraction of Palm Oil (TRF)
Drug · Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
35 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 10, 2019 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Liking, Acceptability and Health Benefits of Grain Products

NCT01403857
View directory record Official record
Conditions
Food Preferences
Interventions
Whole grain foods, Refined grains
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional

EMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression

NCT04266431
View directory record Official record
Conditions
Prostatic Neoplasm
Interventions
EMPOWER
Behavioral
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 11, 2025 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Mindfulness-Based Blood Pressure Reduction: Stage 2a RCT

NCT03256890
View directory record Official record
Conditions
Hypertension, Prehypertension
Interventions
MB-BP Intervention, Enhanced Usual Care Control
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Sep 6, 2026, 1:59 AM EDT
Recruiting Not applicable Interventional

Whole Foods for Teens: A Pilot Dietary Intervention to Reduce Body Adiposity in Adolescents With Obesity

NCT06464497
View directory record Official record
Conditions
Obesity, Childhood, Diet, Healthy, Body Weight Changes
Interventions
Whole Foods MyPlate Group
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
10 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Measuring Daily Grain Intake Study

NCT04104581
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Control Refined Grain Diet, Low Whole Grain Oat Diet, High Whole Grain Oat Diet, Low Whole Grain Wheat Diet, High Whole Grain Wheat Diet
Other
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
21 Years to 75 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated May 10, 2020 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The First Twenty (TF20) for Volunteer Firefighters in a Clinic Based Setting

NCT02760628
View directory record Official record
Conditions
Obesity
Interventions
The First Twenty (TF20), Life Simple 7 (LS7)
Behavioral
Lead sponsor
National Development and Research Institutes, Inc.
Other
Eligibility
18 Years and older
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Leawood, Kansas • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Sep 6, 2026, 1:59 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bad Genes or Genes Behaving Badly

NCT01041664
View directory record Official record
Conditions
Body Composition, Energy Balance, Metabolism
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
3 Years to 7 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 24, 2019 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Discovering Healthcare Innovations to Address Disparities in Stroke (DIADS)

NCT01892592
View directory record Official record
Conditions
Hypertension
Interventions
Diet and Lifestyle
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Early Phase 1 Interventional Results available

Investigating the Role of the Polyol Pathway in the Central Nervous System Production of Fructose

NCT03469492
View directory record Official record
Conditions
Hyperglycaemia (Diabetic)
Interventions
Insulin, exercise, Dietary counseling
Drug · Behavioral · Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 4, 2024 · Synced Sep 6, 2026, 1:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Dietary Guidelines 3 Diet Patterns Study (DG3D): Phase 2

NCT05254496
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Dietary Intervention Classes
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ADAPT-Altering Diet for African American Populations to Treat Hypertension

NCT00621569
View directory record Official record
Conditions
Hypertension
Interventions
Dietary Approaches to Stop Hypertension-The DASH diet, Intervention with no dietary component - information regarding useful life skills
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
25 Years and older
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 17, 2013 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Interactive Multirisk-Factor Intervention for Hypertension (HTN) Blacks

NCT00207194
View directory record Official record
Conditions
Hypertension
Interventions
Automated Telephone Program, Health Behavior Education
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
35 Years and older
Enrollment
337 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 15, 2016 · Synced Sep 6, 2026, 1:59 AM EDT
Completed Not applicable Interventional

Nutrition for Asthmatics with Obesity

NCT05222451
View directory record Official record
Conditions
Asthma, Obesity
Interventions
DGA Diet, MCT Diet, KETO Diet
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Sep 6, 2026, 1:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Team Lifestyle Immersion Hypertension Control Project

NCT07201948
View directory record Official record
Conditions
Hypertension
Interventions
Lifestyle Immersion Intervention that will address Nutrition, Physical Fitness, and BP Self-Monitoring3 Elements:
Behavioral
Lead sponsor
Meharry Medical College
Other
Eligibility
30 Years to 80 Years
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 6, 2026, 1:59 AM EDT