- Conditions
- Brain Tumors
- Interventions
- 5-aminolevulinic acid
- Drug
- Lead sponsor
- David W. Roberts
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 540 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2028
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
Search Results
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Showing 1–24
of 131
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Oral Leukoplakia
- Interventions
- aminolevulinic acid hydrochloride, photodynamic therapy, laboratory biomarker analysis
- Drug · Other
- Lead sponsor
- National Cancer Institute (NCI)
- NIH
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • Milwaukee, Wisconsin
- Conditions
- Actinic Keratosis
- Interventions
- Broad Area ALA 1-hour incubation, Broad Area ALA 2 hour incubation, broad area ALA 3-hour incubation, Spot ALA 2 hour incubation, Vehicle PDT, Blue Light Treatment
- Drug · Device
- Lead sponsor
- DUSA Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 235 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 13
- States / cities
- La Jolla, California • Los Angeles, California • San Diego, California + 10 more
- Conditions
- Keratosis, Actinic
- Interventions
- Aminolevulinic Acid (ALA), BLU-U
- Drug · Device
- Lead sponsor
- DUSA Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- San Diego, California • Carmel, Indiana • Austin, Texas
- Conditions
- Actinic Keratosis, Keratosis, Actinic, Keratosis
- Interventions
- BF-200 ALA and red light LED lamp
- Combination Product
- Lead sponsor
- Biofrontera Bioscience GmbH
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 112 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 9
- States / cities
- Phoenix, Arizona • Greenwood Village, Colorado • Indianapolis, Indiana + 5 more
- Conditions
- Actinic Keratosis
- Interventions
- Microneedle, Aminolevulinic Acid, Blue light
- Device · Drug · Radiation
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 51 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Facial Cutaneous Squamous Cell Carcinoma in Situ
- Interventions
- Aminolevulinic Acid 20% Topical Solution with Blue Light
- Combination Product
- Lead sponsor
- The Center for Clinical and Cosmetic Research
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Aventura, Florida
- Conditions
- Brain Cancer
- Interventions
- Fluorescein, Fluorescein + ALA
- Drug
- Lead sponsor
- David W. Roberts
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2028
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Brain Neoplasms
- Interventions
- Tumor fluorescence
- Drug
- Lead sponsor
- Southern Illinois University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2021
- U.S. locations
- 1
- States / cities
- Springfield, Illinois
- Conditions
- Lung Cancer in Normal and Malignant Tumors
- Interventions
- ALA-induced Fluorescence
- Drug
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2014
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Recurrent Glioblastoma, Glioblastoma Multiforme, GBM
- Interventions
- 5-ALA and Low-Intensity Focused Ultrasound (SDT)
- Combination Product
- Lead sponsor
- Shayan Moosa, MD
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma, Adult Giant Cell Glioblastoma, Adult Glioblastoma, Adult Gliosarcoma, Adult Mixed Glioma, Recurrent Adult Brain Tumor
- Interventions
- aminolevulinic acid, laboratory biomarker analysis, therapeutic conventional surgery
- Drug · Other · Procedure
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2010
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Actinic Keratoses
- Interventions
- BF-200 ALA and red light LED lamp, Vehicle and red light LED lamp
- Combination Product
- Lead sponsor
- Biofrontera Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 172 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 14
- States / cities
- Phoenix, Arizona • Greenwood Village, Colorado • Delray Beach, Florida + 10 more
- Conditions
- Bladder Cancer
- Interventions
- hexaminolevulinate, biopsy, cystoscopy
- Drug · Procedure
- Lead sponsor
- Photocure
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2001
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Actinic Keratosis
- Interventions
- 5-ALA plus Blu-Light, 5-FU, Imiquimod or treatment with cryotherapy
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 95 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Keratosis, Actinic
- Interventions
- MAL Cream, Vehicle cream
- Drug
- Lead sponsor
- Galderma R&D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 52
- States / cities
- Fort Smith, Arkansas • Encinitas, California • Fountain Valley, California + 43 more
- Conditions
- Glioma
- Interventions
- 5-ala
- Drug
- Lead sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Erythropoietic Protoporphyria (EPP), X Linked Erythropoietic Protoporphyria
- Interventions
- Isoniazid
- Drug
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Actinic Keratosis
- Interventions
- Photodynamic therapy (PDT), Vitamin D3
- Drug
- Lead sponsor
- Case Comprehensive Cancer Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Primary Glioblastoma
- Interventions
- 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 200 J/cm^2, 5-ALA HCl intraoperative Photodynamic Therapy (PDT) at 400 J/cm^2
- Combination Product
- Lead sponsor
- Hemerion Therapeutics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Actinic Keratosis
- Interventions
- Aminolevulinic Acid (ALA), Topical Solution Vehicle, Blue Light Photodynamic Therapy Illuminator (BLU-U)
- Drug · Device
- Lead sponsor
- DUSA Pharmaceuticals, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 269 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 13
- States / cities
- Fremont, California • San Diego, California • Aventura, Florida + 10 more
- Conditions
- Brain Neoplasms
- Interventions
- HIVEN Medical Device
- Device
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Superficial Basal Cell Carcinoma
- Interventions
- Photodynamic therapy (PDT) (ALA-PDT, Ameluz®-PDT), Placebo Photodynamic therapy (PDT) (vehicle to BF-200 ALA containing no active ingredient)
- Combination Product
- Lead sponsor
- Biofrontera Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 187 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2029
- U.S. locations
- 18
- States / cities
- Phoenix, Arizona • Fountain Valley, California • San Diego, California + 14 more
- Conditions
- Acne Vulgaris
- Interventions
- 5-ALA with Blu-U Light, 5-ALA with Candela V-beam Pulse Dye Laser
- Drug
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years to 79 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 1
- States / cities
- Chicago, Illinois