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ClinicalTrials.gov public records Last synced Sep 6, 2026, 5:35 AM EDT

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Showing 1–19 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Anatomic Total Shoulder Replacement Clear all
Enrolling by invitation No phase listed Observational

Tornier HRS (Humeral Reconstruction System) Study (REVIVE)

NCT05500066
View directory record Official record
Conditions
Rheumatoid Arthritis, Osteoarthritis Shoulder, Fractures Humerus, Avascular Necrosis, Correction of Functional Deformity, Traumatic Arthritis, Revision of Other Devices if Sufficient Bone Stock Remains, Rotator Cuff Tears
Interventions
Tornier HRS (HUMERAL RECONSTRUCTION SYSTEM) shoulder system
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2036
U.S. locations
4
States / cities
Denver, Colorado • Bradenton, Florida • Tampa, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 6, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Zimmer Biomet Shoulder Arthroplasty PMCF

NCT04984291
View directory record Official record
Conditions
Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Interventions
Alliance Glenoid, Identity Stem
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
20 Years and older
Enrollment
584 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2033
U.S. locations
12
States / cities
Irvine, California • Golden, Colorado • Chicago, Illinois + 9 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Comparing the Outcome of Cemented All-Polyethylene Pegged vs. Keeled Components Through a Subscapularis Tenotomy or a Subscapularis Peel

NCT03735173
View directory record Official record
Conditions
Arthropathy Shoulder, Shoulder Pain, Shoulder Osteoarthritis, Shoulder Arthritis, Shoulder Arthropathy Associated With Other Conditions, Necrosis of Bone, Arthritis, Inflammatory Arthritis
Interventions
ReUnion TSA, pegged design, ReUnion TSA, keeled design
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional Results available

Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty

NCT01905241
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
Anatomic TSA using RTI, Anatomic Total Shoulder Arthroplasty
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty

NCT06831422
View directory record Official record
Conditions
Shoulder Arthroplasty, Positive C. Acnes Culture
Interventions
Povidone-Iodine, Hydrogen Peroxide, Xperience Antimicrobial Wash, Bacterial Cultures, Shoulder Arthroplasty
Device · Diagnostic Test · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Sep 6, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Increased Home-based Physical Therapy Adherence Using BAND Connect's VirtuaCare™ Platform

NCT05876208
View directory record Official record
Conditions
Shoulder Injuries
Interventions
BAND Connect's VirtuaCare™ platform, Standard of Care Physical Therapy
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 6, 2026, 5:35 AM EDT
Enrolling by invitation Not applicable Interventional

Pyrocarbon Hemiarthroplasty Versus Total Shoulder Arthroplasty for the Treatment of Glenohumeral Osteoarthritis

NCT07226388
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Hemiarthroplasty with pyrocarbon, Anatomic total shoulder arthroplasty
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 6, 2026, 5:35 AM EDT
Not listed Not applicable Interventional

Fixed Inclination Humeral Cut

NCT03922763
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Anatomical cut, Cutting guide
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Sep 6, 2026, 5:35 AM EDT
Enrolling by invitation No phase listed Observational

MDR - Comprehensive Primary/Micro Stem & Versa-Dial Ti Humeral Head

NCT04003311
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Disease, Shoulder Arthritis
Interventions
Comprehensive Primary Micro Stem, Comprehensive Anatomic Versa-Dial Titanium Humeral Head
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
4
States / cities
Boise, Idaho • Royal Oak, Michigan • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional Results available

Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments

NCT01801241
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
Anatomic TSA using IRI Instrumentation, Anatomic Total Shoulder Arthroplasty
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

A Study Comparing Shoulder Replacement Techniques For Patients With Shoulder Arthritis And An Intact Rotator Cuff

NCT07584356
View directory record Official record
Conditions
Shoulder Arthritis
Interventions
aTSA, rTSA
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years to 85 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 6, 2026, 5:35 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

TSA Versus RSA in Patients >75

NCT04827277
View directory record Official record
Conditions
Total Shoulder Arthoplasty
Interventions
Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
75 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Investigation of Intravenous Tranexamic Acid With Anatomic and Reverse Total Shoulder Arthroplasty

NCT02569658
View directory record Official record
Conditions
Blood Loss, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty, Transfusion, Tranexamic Acid
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
Not listed
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional Results available

Comparison of Glenoid Position Using SmartBones

NCT03035318
View directory record Official record
Conditions
Anatomic Total Shoulder Arthroplasty
Interventions
DePuy Global® Anchor Peg Glenoid Instrumentation, DePuy Global® Anchor Peg Instrumentation with SmartBone™, IRI with SmartBone™, RTI with SmartBone™, IRI with SmartBase
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 17, 2021 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

NCT04415931
View directory record Official record
Conditions
Shoulder Osteoarthritis, Cuff Tear Arthropathy, Massive Rotator Cuff Tear
Interventions
Local infiltration analgesia, Interscalene block
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 13, 2023 · Synced Sep 6, 2026, 5:35 AM EDT
Withdrawn Not applicable Interventional

Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

NCT06513559
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Anatomic total shoulder replacement, Reverse total shoulder replacement
Device
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 6, 2026, 5:35 AM EDT
Terminated No phase listed Observational Results available

A Post-Market Clinical Evaluation of the ReUnion TSA System

NCT03858517
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
ReUnion TSA System
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Peoria, Illinois • Nashville, Michigan • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2025 · Synced Sep 6, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Subscapularis Strength After Total Shoulder Arthroplasty

NCT03854357
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Subscapularis Rehabilitation, Standard Rehabilitation
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Sep 6, 2026, 5:35 AM EDT
Enrolling by invitation No phase listed Observational

Subscapularis-Sparing Total Shoulder Arthroplasty

NCT07410650
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
Subscapularis-Sparing Total Shoulder Arthroplasty
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 6, 2026, 5:35 AM EDT