Independent directory Public ClinicalTrials.gov records United States
Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 2, 2026, 12:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
Terminated No phase listed Observational Accepts healthy volunteers Results available

SCANREP: Reliability of 3D Lower Limb Scanning

NCT04032041
Conditions
Foot Injuries and Disorders
Interventions
Structure Sensor, Caliper
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Ataxia
Interventions
Home wearing schedule
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

NCT06127264
Conditions
Healthy, Ankle Foot Orthosis (AFO), Peripheral Neuropathy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Musculoskeletal Injury, Musculoskeletal Diseases, Peripheral Nervous System Diseases
Interventions
Tall Soft, Tall Firm, Short Soft, Short Firm
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Parkinson's Disease
Interventions
Ankle foot orthosis
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Results available

Ankle Foot Orthosis Comparative Effect

NCT03901053
Conditions
Foot Injuries and Disorders
Interventions
Reaktiv AFO, PhatBrace AFO
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Iowa City, Iowa • Bethesda, Maryland • Minneapolis, Minnesota
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress

NCT04562896
Conditions
Ankle Fractures, Post-traumatic Osteoarthritis, Osteoarthritis Ankle
Interventions
Custom Carbon Fiber Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Completed Not applicable Interventional Results available

Iterative Design of Custom Dynamic Orthoses

NCT04800510
Conditions
Adult ALL, Healthy
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 50 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis, Post-Cerebrovascular Accident (CVA) Hemiparesis
Interventions
Ness L300, Ankle-foot orthosis
Device
Lead sponsor
Bioness Inc
Industry
Eligibility
18 Years and older
Enrollment
197 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
11
States / cities
Downey, California • Long Beach, California • San Diego, California + 8 more
Conditions
Lower Extremity Injuries
Interventions
Visual Feedback
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Everett, Washington
Completed Not applicable Interventional Results available

Ankle-foot Orthoses for Peripheral Artery Disease

NCT02280200
Conditions
Peripheral Artery Disease
Interventions
AFO to improve outcomes
Device
Lead sponsor
University of Minnesota
Other
Eligibility
40 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Missoula, Montana
Conditions
Hemiplegia, Spastic
Interventions
Not listed
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
West Orange, New Jersey
Conditions
Arthropathy Due to Bleeding From Hemophilia
Interventions
Carbon fiber ankle foot orthosis versus cast boot
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
5 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Terminated Not applicable Interventional Results available

Effectiveness of Ankle Foot Orthoses on Gait in Multiple Sclerosis

NCT01796860
Conditions
Multiple Sclerosis
Interventions
AFO
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
21 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Dallas, Texas
Active, not recruiting Not applicable Interventional

C-Brace II Spinal Cord Injury

NCT03930056
Conditions
Spinal Cord Injury
Interventions
C-Brace II, Traditional Care KAFO intervention
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Charcot Marie Tooth Disease (CMT)
Interventions
Ankle-foot Orthoses
Device
Lead sponsor
Bopha Chrea
Other
Eligibility
25 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
North Liberty, Iowa
Conditions
Posterior Tibial Tendon Dysfunction
Interventions
Bracing, Strengthening exercises, Stretching exercises
Device · Other
Lead sponsor
Ithaca College
Other
Eligibility
40 Years to 80 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Rochester, New York
Conditions
Walking Aided by a Leg Brace in Stroke Subjects
Interventions
ADR™ brace resistance, Conventional brace resistance (using hard stops)
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
21 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Conditions
Traumatic Lower Limb Injury
Interventions
Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Foot Injury
Interventions
Modular Carbon Fiber Custom Dynamic Orthosis (CDO), Mono Carbon Fiber Custom Dynamic Orthosis (CDO)
Device
Lead sponsor
Jason Wilken
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
San Diego, California • Iowa City, Iowa • Minneapolis, Minnesota + 2 more
Completed Not applicable Interventional Results available

Bracing for Walking in Parkinson's Disease

NCT03192046
Conditions
Gait Disorders, Neurologic, Parkinson Disease
Interventions
Carbon Fiber Ankle Foot Orthosis (AFO), Standardized walking/exercise program
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
30 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Stroke
Interventions
Dynamic ankle-foot orthosis
Device
Lead sponsor
University of Delaware
Other
Eligibility
21 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Newark, Delaware
Completed Not applicable Interventional Results available

WalkAide Compared to Ankle-Foot Orthosis (AFO) in Stroke Patients

NCT01087957
Conditions
Stroke
Interventions
WalkAide, Ankle-Foot Orthosis (AFO)
Device · Other
Lead sponsor
Innovative Neurotronics
Industry
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
29
States / cities
Loma Linda, California • Los Angeles, California • Pomona, California + 25 more
Conditions
Plantar Fasciitis, Chronic
Interventions
minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
Device
Lead sponsor
University of South Florida
Other
Eligibility
50 Years to 70 Years
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Tampa, Florida