Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 2, 2026, 8:00 PM EDT

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Showing 1–24 of 98 matching trials from the live ClinicalTrials.gov search.
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Conditions
Multiple Sclerosis
Interventions
The Kessler Foundation modified Story Memory Technique® (KF-mSMT®), Aerobic Exercise Training (AET) plus Virtual Reality (IDEAL), Stretching and Toning (S/T)
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
East Hanover, New Jersey
Conditions
Avascular Necrosis of the Talus, Talar Osteochondral Defect of Ankle, Talar Dysfunction
Interventions
Total Talus Replacement (TTR)
Device
Lead sponsor
Restor3D
Industry
Eligibility
22 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2031
U.S. locations
1
States / cities
Charlotte, North Carolina
Conditions
Ankle Foot Orthosis (AFO), Stroke Patients, Post-Stroke Hemiparesis
Interventions
Pre-fabricated (PF) ankle-foot orthosis (AFO), Carbon-strut (CS) ankle-foot orthosis (AFO), Multifunctional articulating (MA) ankle-foot orthosis (AFO)
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Downey, California • Jacksonville, Florida • Charleston, South Carolina + 1 more
Conditions
Gait
Interventions
None- Observational Study
Other
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years to 60 Years
Enrollment
244 participants
Timeline
2019 – 2024
U.S. locations
10
States / cities
Lexington, Kentucky • Baltimore, Maryland • Bethesda, Maryland + 7 more
Conditions
Muscle Tightness
Interventions
Instrument Assisted Soft Tissue Mobilization, Rearfoot joint mobilization, Static stretching/ROM exercises
Procedure · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Lateral Ankle Sprain
Interventions
Sham ("laying of hands") intervention, Grade IV AP joint mobilizations
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Conditions
Parkinson Disease
Interventions
Osteopathic Manipulative Treatment (OMT), Light Touch
Procedure · Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
La Jolla, California
Conditions
Ankle Sprain
Interventions
High velocity, low amplitude stretch, Slow, mobilization stretch, Passive Positioning
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Amputation
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
1,572 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Miami, Florida • Seattle, Washington
Conditions
Stroke
Interventions
Smart AFO
Device
Lead sponsor
Orthocare Innovations, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
3
States / cities
Troy, Michigan • Salt Lake City, Utah • Edmonds, Washington
Not listed Not applicable Interventional Accepts healthy volunteers

The Acute Impact of Yoga-based Stretching on Inflammation and Its Resolution

NCT04444102
Conditions
Inflammation, Fascia; Inflammation, Musculoskeletal Pain, Lower Back Pain, Neck Pain
Interventions
Yoga-based stretching
Procedure
Lead sponsor
Harvard University Faculty of Medicine
Other
Eligibility
40 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Walking Function in Diabetic Peripheral Neuropathy

NCT05965336
Conditions
Diabetic Peripheral Neuropathy
Interventions
Clinical Evaluation, Evaluation of Passive Ankle Stiffness, Gait Biomechanics, Gait Biofeedback, Plantar Pressure Biofeedback Gait Training, Propulsion Biofeedback Gait Training
Other
Lead sponsor
Florida Institute for Human and Machine Cognition
Other
Eligibility
45 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pensacola, Florida
Conditions
Cerebral Palsy
Interventions
Smart Ankle-Foot Orthosis, 5-Azacitidine, Placebo
Device · Drug
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
8 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Traumatic Brain Injury
Interventions
Motor relearning training with wearable ankle robot, Passive stretching with wearable ankle robot, Gamed-based active movement training with wearable ankle robot, Passive movement with limited wearable ankle robot, Active movement training with limited wearable ankle robot, Ankle/Wrist torque and motion measurement with limited wearable ankle/wrist robot
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
30 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Mobility Exercises for Gait (MEG Neuroplasticity Project)

NCT03555708
Conditions
Cerebral Palsy
Interventions
Physical Therapy
Other
Lead sponsor
University of Nebraska
Other
Eligibility
9 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Ankle Fractures
Interventions
Ankle Muscle Power (AMP) program, Standard of Care
Other · Behavioral
Lead sponsor
Brian W. Noehren
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Spastic Hemiplegia
Interventions
Ankle Dorsiflexion Dynasplint, Standard of care
Device · Other
Lead sponsor
Dynasplint Systems, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Different Types of Cupping Therapy and Ankle Range of Motion

NCT06513078
Conditions
Healthy
Interventions
Static cupping, Static sham cupping, Dynamic cupping, Dynamic sham cupping
Other
Lead sponsor
Northern Michigan University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Marquette, Michigan
Conditions
Bone Sarcoma, Osteosarcoma, Chondrosarcoma, Ewing's Sarcoma, Osseous Sarcoma, Bone Neoplasm
Interventions
Toronto Extremity Salvage Score, Musculoskeletal Tumor Society Score, Timed Get Up and Go Test, Orthogonal Radiographs, Weight Bearing for lower extremities only, Range of Motion
Behavioral · Diagnostic Test
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
4 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
5
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Harrison, New York + 2 more
Completed Not applicable Interventional Results available

Functional Movement Retraining After Hip Replacement

NCT01878175
Conditions
Arthroplasty, Replacement, Hip
Interventions
Functional Movement Retraining
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Durham, North Carolina
Conditions
Transtibial Amputation - Unilateral
Interventions
MIT Variable Stiffness Prosthesis v1, MIT Variable Equilibrium Angle Prosthesis v1, MIT Sliding Beam Passive Prosthesis, Ossur Pro-Flex XC, Blatchford Elan Variable-Dampening Prosthesis, Ossur Proprio Variable Angle Prosthesis, MIT Variable Stiffness Prosthesis v2, MIT Variable Equilibrium Angle Prosthesis v2
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Burlington, Massachusetts • Cambridge, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults

NCT05822466
Conditions
Accidental Fall
Interventions
Virtual tai ji quan: moving for better balance intervention (V-TJQMBB), Virtual multimodal exercise intervention (V-Multimodal)
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
65 Years to 90 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Springfield, Oregon
Completed Not applicable Interventional Results available

Vestibular Rehabilitation and Dizziness

NCT01729039
Conditions
Dizziness
Interventions
standard balance rehabilitation, gaze stability, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Decatur, Georgia • Mountain Home, Tennessee
Active, not recruiting Not applicable Interventional

Ankle Instability Using Foot Intensive Rehabilitation

NCT04493645
Conditions
Ankle Injuries, Ankle Sprains
Interventions
Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
Behavioral
Lead sponsor
Matthew Hoch
Other
Eligibility
18 Years to 44 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky