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Showing 1–24 of 84 matching trials from the live ClinicalTrials.gov search.
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study

NCT03617302
Conditions
Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension, Cognitive Decline
Interventions
Experimental: Nitrate-containing, Placebo: Nitrate-depleted
Drug
Lead sponsor
Gary L. Pierce, PhD
Other
Eligibility
50 Years to 79 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Terminated Not applicable Interventional Accepts healthy volunteers

Effect of Selenium Intervention on Inflammation in Older Adults

NCT01289925
Conditions
Inflammation
Interventions
Selenium, Sugar Pill Placebo
Dietary Supplement · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
70 Years to 110 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Asthma
Interventions
Lifestyle Factors, Customized use of Dietary Supplements, Currently Accepted Asthma Care Guidelines
Behavioral · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
19 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Acquiring and Targeting Heat Exposures Necessary for Action

NCT05678738
Conditions
Heat Intolerance, Heat Stress, Fatigue; Heat
Interventions
Antioxidant Berry Supplementation, Acute and Chronic Exercise-Heat Stress, Placebo (non-juice) Supplementation
Dietary Supplement · Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Storrs, Connecticut
Completed Not applicable Interventional Accepts healthy volunteers

Effect of 6-week Strawberry Supplementation on Insulin Action (STR2)

NCT01457612
Conditions
Insulin Resistance, Nutritional Disease, Metabolic Disease
Interventions
Strawberry, Placebo1, Placebo2
Dietary Supplement
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Resvida, a Comparison With Calorie Restriction Regimen

NCT00823381
Conditions
Obesity, Metabolic Syndrome, Diabetes, Aging
Interventions
resveratrol, placebo, Calorie Restriction
Dietary Supplement · Other · Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 70 Years · Female only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
St Louis, Missouri
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Adult Eating Habits

NCT05550818
Conditions
Eating Behavior, Eating Habit
Interventions
High Ultra Processed Food Diet, No Ultra Processed Food Diet
Other
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
18 Years to 25 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Blacksburg, Virginia • Roanoke, Virginia
Completed No phase listed Observational Accepts healthy volunteers

Lifestyle and Fertility Study on Antioxidant Status, Diet and Early Pregnancy

NCT00642590
Conditions
Infertility, Pregnancy, Fertility, Nutrition, Life Style
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 39 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2020
U.S. locations
2
States / cities
Concord, New Hampshire • University Park, Pennsylvania
Conditions
Insulin Resistance, Mild Cognitive Impairment, Cognitive Decline, Neurodegenerative Disorders
Interventions
Sabroxy®, Placebo
Dietary Supplement · Other
Lead sponsor
SF Research Institute, Inc.
Network
Eligibility
40 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Conditions
Diet, Healthy
Interventions
Standard Process Hemp Oil Complex
Dietary Supplement
Lead sponsor
Standard Process Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Kannapolis, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Antioxidants on Human Macular Pigments

NCT00718653
Conditions
Eye Health
Interventions
Lutein, Lutein plus green tea extract
Dietary Supplement
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
50 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

The Effects of an Antioxidant Formulation on Ocular Blood Flow

NCT01930487
Conditions
Primary Open Angle Glaucoma
Interventions
dietary supplement with antioxidants, Placebo
Dietary Supplement
Lead sponsor
ScienceBased Health
Industry
Eligibility
30 Years to 70 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Indianapolis, Indiana
Enrolling by invitation Not applicable Interventional

PET-MRI in Chronic Traumatic Brain Injury (CTBI)

NCT03241732
Conditions
Chronic Traumatic Brain Injury
Interventions
Anti-inflammatory Diet, N-acetyl Cysteine, Neuro Emotive Technique
Other · Dietary Supplement · Behavioral
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Villanova, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Absorption, Metabolism, and Excretion of (-)-[2-14C]Epicatechin in Humans

NCT01969994
Conditions
ADME
Interventions
Controlled dietary background, (-)-[2-14C]epicatechin intake
Other
Lead sponsor
The Institutes for Pharmaceutical Discovery, LLC
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Madison, Wisconsin
Conditions
Cancer Survivor With History of Anthracycline Chemotherapy
Interventions
Beetroot juice, Black currant juice
Dietary Supplement
Lead sponsor
Kansas State University
Other
Eligibility
21 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Manhattan, Kansas
Conditions
Obesity, Blood Glucose, High
Interventions
Micronutrient-dense plant-rich Intervention
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Flagstaff, Arizona
Conditions
Autism Spectrum Disorders
Interventions
Whey Protein, Rice Protein (Placebo)
Dietary Supplement
Lead sponsor
Nova Southeastern University
Other
Eligibility
3 Years to 5 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Fort Lauderdale, Florida
Conditions
Cardiovascular Disease, Hyperlipidemia
Interventions
Avocado Diet, Lower-Fat Diet, Moderate Fat Diet
Other
Lead sponsor
Penn State University
Other
Eligibility
21 Years to 70 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
University Park, Pennsylvania
Completed Phase 2 Interventional Accepts healthy volunteers

Benefits of Walnuts for Male Reproductive Health

NCT01505140
Conditions
Infertility, Nutrition Disorders
Interventions
Whole walnuts
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 35 Years · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Healthy Elder People
Interventions
Feru-guard, Placebo
Dietary Supplement · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
65 Years to 89 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Schizophrenia
Interventions
Olanzapine, Omega 3, Vitamin E+C
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2005
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Diabetes Mellitus, Type 1
Interventions
Antioxidant supplement, Diabetes treatment, Regular Insulin
Dietary Supplement · Other · Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
12 Years to 21 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Terminated Not applicable Interventional

BREATHE-Easy Trial

NCT03200522
Conditions
Asthma
Interventions
Prudent diet, Western diet
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Milk Intervention Study for Brain Aging

NCT02957422
Conditions
Brain Aging
Interventions
1% Milk, Control
Dietary Supplement
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
60 Years to 89 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas