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ClinicalTrials.gov public records Last synced Sep 27, 2026, 4:47 AM EDT

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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Aortic valve repair Clear all
Recruiting No phase listed Observational

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

NCT04545502
View directory record Official record
Conditions
Aneurysm, Dissection, Aortic Root Aneurysm, Aortic Root Dissection, Carotid Artery Injuries, Aortic Arch, Bypass Extremity Graft, Occlusive Vascular Disease, Aortic Diseases
Interventions
Gelsoft Plus Vascular Graft, Vascular Bypass Graft, Cardiovascular Patch, Gelweave Vascular Graft, Gelweave Valsalva Vascular Graft
Device
Lead sponsor
Vascutek Ltd.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2037
U.S. locations
10
States / cities
Aurora, Colorado • Tampa, Florida • Indianapolis, Indiana + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 27, 2026, 4:47 AM EDT
Completed Phase 1 Interventional

FEIBA and Use of Blood Products in Cardiac Surgery

NCT02577614
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
FEIBA, Normal Saline
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 13, 2020 · Synced Sep 27, 2026, 4:47 AM EDT
Recruiting Not applicable Interventional

Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients

NCT02537769
View directory record Official record
Conditions
Tricuspid Regurgitation, Heart Failure NYHA Class III, Heart Failure NYHA Class IV
Interventions
Left ventricular assist device (LVAD), Tricuspid Valve Repair (TVR)
Device · Procedure
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced Sep 27, 2026, 4:47 AM EDT
Active, not recruiting No phase listed Observational

Post Market Clinical Follow-Up Study in Patients Treated With the On-X Ascending Aortic Prosthesis (AAP)

NCT05082454
View directory record Official record
Conditions
Aortic Valve Disease
Interventions
Open repair
Device
Lead sponsor
JOTEC GmbH
Industry
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
3
States / cities
Danville, Pennsylvania • Houston, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Sep 27, 2026, 4:47 AM EDT
Recruiting No phase listed Observational

Effect of Fetal Aortic Valvuloplasty on Outcomes

NCT05386173
View directory record Official record
Conditions
Congenital Heart Disease, Aortic Valve Stenosis, Fetal Cardiac Disorder, Hypoplastic Left Heart Syndrome
Interventions
Fetal aortic balloon dilatation
Procedure
Lead sponsor
Queen Silvia Children's Hospital, Gothenburg, Sweden
Other
Eligibility
23 Weeks to 31 Weeks
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2029
U.S. locations
2
States / cities
San Francisco, California • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

Prospective Balloon Aortic Valvuloplasty

NCT02122900
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Dallas, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2017 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

Post-Market Surveillance Registry to Monitor Performance and Safety of V8 Device

NCT02099942
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
V8 Balloon Aortic Valvuloplasty (BAV) Catheter
Device
Lead sponsor
InterValve, Inc.
Industry
Eligibility
Not listed
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
7
States / cities
Los Angeles, California • Minneapolis, Minnesota • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

Balloon Aortic Valvuloplasty During Surgical Aortic Valve Replacement

NCT00584116
View directory record Official record
Conditions
Aortic Stenosis
Interventions
Not listed
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 29, 2017 · Synced Sep 27, 2026, 4:47 AM EDT
Completed Not applicable Interventional Results available

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation

NCT01694563
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Interventions
Synergy Ablation System
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
49
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Los Angeles, California + 41 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Sep 27, 2026, 4:47 AM EDT
Terminated No phase listed Observational

Evaluation of ARi With OpSens SavvyWire

NCT06295068
View directory record Official record
Conditions
Aortic Valve Insufficiency
Interventions
Transcatheter Aortic Valve Replacement (TAVR), Balloon Aortic Valvuloplasty (BAV)
Device
Lead sponsor
Opsens, Inc.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Sep 27, 2026, 4:47 AM EDT
Withdrawn No phase listed Observational

Left Ventricular Volume and Ejection Fraction: Validation of Real Time 3 Dimensional Transesophageal Echocardiography

NCT01734174
View directory record Official record
Conditions
3D Transesophageal and Transthoracic Echocardiogram
Interventions
transesophageal echocardiography (TEE), thermodilution, transthoracic echocardiography (TTE)
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced Sep 27, 2026, 4:47 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome

NCT06342999
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome
Interventions
Fetal Aortic Valvuloplasty Procedure, Emerge Monorail and Over-The-Wire PTCA Dilatation Catheter, Trek RX and Mini Trek RX Coronary Dilatation Catheter
Procedure · Device
Lead sponsor
Mauro H. Schenone
Other
Eligibility
Up to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2036
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 27, 2026, 4:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fetal Intervention for Aortic Stenosis and Evolving Hypoplastic Left Heart Syndrome

NCT01736956
View directory record Official record
Conditions
Aortic Stenosis, Hypoplastic Left Heart Syndrome
Interventions
Fetal Aortic Valvuloplasty
Procedure
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years and older · Female only
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2023 · Synced Sep 27, 2026, 4:47 AM EDT
Completed Not applicable Interventional Results available

Comparing the Effectiveness of a Mitral Valve Repair Procedure in Combination With Coronary Artery Bypass Grafting (CABG) Versus CABG Alone in People With Moderate Ischemic Mitral Regurgitation

NCT00806988
View directory record Official record
Conditions
Mitral Valve Insufficiency, Coronary Artery Disease
Interventions
Mitral Valve Repair, CABG
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
19
States / cities
Los Angeles, California • Atlanta, Georgia • Marietta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2017 · Synced Sep 27, 2026, 4:47 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Radiation Following Percutaneous Balloon Aortic Valvuloplasty to Prevent Restenosis

NCT00538759
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
External beam radiation therapy, Sham Control
Device · Other
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
75 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Minneapolis, Minnesota • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

Quality of Life After Open Heart Surgery in Older Patients

NCT00248898
View directory record Official record
Conditions
Open Heart Surgery Patients
Interventions
Cardiac Surgery
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
90 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 27, 2026, 4:47 AM EDT
Recruiting No phase listed Observational

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

NCT05002543
View directory record Official record
Conditions
Cardiac Valve Disease
Interventions
Not listed
Lead sponsor
Corcym S.r.l
Industry
Eligibility
Not listed
Enrollment
2,150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
9
States / cities
Indianapolis, Indiana • New Orleans, Louisiana • Portland, Maine + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

SUrgical Versus PERcutaneous AXillary Artery International Registry

NCT04589962
View directory record Official record
Conditions
Surgical and the Percutaneous Approach to the Upper Extremity Access
Interventions
access axillary or brachial artery
Other
Lead sponsor
IRCCS San Raffaele
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Sep 27, 2026, 4:47 AM EDT
Terminated No phase listed Observational

HAART Annuloplasty Device Valve Repair Registry

NCT04035356
View directory record Official record
Conditions
Aortic Valve Insufficiency, Aortic Aneurysm
Interventions
Aortic valve repair
Device
Lead sponsor
Biostable Science & Engineering
Industry
Eligibility
Not listed
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
5
States / cities
Indianapolis, Indiana • Ann Arbor, Michigan • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational

Testing Automated Echocardiography

NCT04943965
View directory record Official record
Conditions
This Study is Being Conducted to Collect Echocardiographic Data to Test the Lumify Ultrasound With Hemodynamic Automation Device
Interventions
Ultrasound imaging
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Sep 27, 2026, 4:47 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biomarkers in Aortic Stenosis - B.A.S.S.

NCT01334801
View directory record Official record
Conditions
Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions
Blood Draw
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older
Enrollment
378 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2020
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 27, 2026, 4:47 AM EDT
Withdrawn No phase listed Observational

Structural Heart and Valve Network PROSPECTIVE Registry

NCT03928639
View directory record Official record
Conditions
Mitral Valve Regurgitation, Heart Failure, Heart Valve Disease, Tricuspid Valve Regurgitation, Aortic Valve Stenosis
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 27, 2026, 4:47 AM EDT
Completed Not applicable Interventional Results available

THE PARTNER TRIAL: Placement of AoRTic TraNscathetER Valve Trial

NCT00530894
View directory record Official record
Conditions
Critical Aortic Stenosis
Interventions
Edwards SAPIEN Transcatheter Heart Valve, Surgical Valve Replacement, medical management and/or balloon aortic valvuloplasty
Device · Other
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
Not listed
Enrollment
1,057 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2017
U.S. locations
22
States / cities
La Jolla, California • Los Angeles, California • Stanford, California + 17 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2017 · Synced Sep 27, 2026, 4:47 AM EDT
Not listed Phase 1Phase 2 Interventional

Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left Ventricle

NCT03079401
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome, Atrioventricular Canal
Interventions
MPC; rexlemestrocel-L
Biological
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 5 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced Sep 27, 2026, 4:47 AM EDT