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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:44 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 258 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Apple Extract Clear all
Terminated Not applicable Interventional Results available

Dual Antiplatelet Therapy Adherence With Reminder App Usage

NCT05071027
View directory record Official record
Conditions
Aneurysm Cerebral (Unruptured)
Interventions
Endovascular Neurosurgery
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Phase 1 Interventional Results available

Purple Grape Juice in Improving Vascular Health in Childhood Cancer Survivors

NCT01043939
View directory record Official record
Conditions
Cardiovascular Disease
Interventions
Purple Grape Juice, Apple Juice
Other
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 30 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 31, 2014 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Nitrate-rich Fruit and Vegetable Supplement on Blood Pressure

NCT03486145
View directory record Official record
Conditions
High Blood Pressure, Flow Mediated Dilation
Interventions
fruit and vegetable juice supplement, Placebo
Dietary Supplement
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 40 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 3, 2018 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Early Phase 1 Interventional Results available

Effects of Flavors on Nicotine Reinforcement in Smokers

NCT03243630
View directory record Official record
Conditions
Nicotine Dependence
Interventions
IV nicotine, Menthol flavor, green apple, green apple and menthol
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 3, 2020 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional

Destiffening and Hypotensive Effects of Whole Milk and Full-fat Dairy Products

NCT02397902
View directory record Official record
Conditions
Hypertension, Prehypertension
Interventions
High fat dairy, Plant-based
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
20 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 1, 2018 · Synced Oct 23, 2026, 4:44 AM EDT
Recruiting Not applicable Interventional

Smartphone Services for Stimulant Use Disorder

NCT07092059
View directory record Official record
Conditions
Stimulant Use Disorder
Interventions
Smartphone digital therapeutic system
Device
Lead sponsor
DynamiCare Health
Industry
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Impact of Fruit Juice, Fruit Juice With Pomace, or Whole Fruit on Glycemic Response

NCT04369716
View directory record Official record
Conditions
Glycemic Response
Interventions
Whole oranges, Whole Apples, Orange juice + orange pomace, Apple juice + apple pomace, Orange juice, Apple juice
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Accuracy of Commercially Available Heart Rate Monitors in Athletes

NCT03612063
View directory record Official record
Conditions
Heart Rate Monitors, Athletes Heart
Interventions
Fitbit Iconic HR and Garmin Vivosmart HR, Fitbit Iconic HR and TomTom Spark 3, Garmin Vivosmart HR and TomTom Spark 3, Fitbit Iconic HR and Apple Watch III, Apple Watch III and Garmin Vivosmart HR, Apple Watch III and TomTom Spark 3
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2019 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional

Accuracy of the Apple Watch Series 4 for Detection of Heart Rhythm: A Pilot Study

NCT03798613
View directory record Official record
Conditions
Heart Rate Fast, Heart Rate Low
Interventions
Apple Watch 4 Series Device, Continuous Telemetry Monitor
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 23, 2026, 4:44 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

AI-Enabled Wearable Monitoring for Detection of Postpartum Depression and Anxiety

NCT07866053
View directory record Official record
Conditions
Postpartum Depression (PPD), Postpartum Anxiety
Interventions
Not listed
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Vitamin C on Iron Absorption

NCT00570895
View directory record Official record
Conditions
Iron Deficiency
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Years to 8 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2020 · Synced Oct 23, 2026, 4:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measuring Volume Using a 3D Scanner and iPad to Grade the Swelling of Legs

NCT06944041
View directory record Official record
Conditions
Limb Volume, Measuring Edema
Interventions
STO3 sensor (Structure Inc., Boulder, CO)
Other
Lead sponsor
The RANE Center for Venous and Lymphatic Diseases at St. Dominic's Hospital
Other
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated May 18, 2025 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Results available

Tetrahydrobiopterin Treatment in Children With Idiopathic Cognitive Developmental Disorders

NCT01141595
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
sapropterin dihydrochloride
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
2 Years to 6 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2014 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional

Apple Watch Heart Failure Study

NCT04510779
View directory record Official record
Conditions
Heart Failure
Interventions
Apple Watch
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging

NCT06125912
View directory record Official record
Conditions
Skin Aging
Interventions
Dime Beauty TBT Cream, Positive Control
Other
Lead sponsor
Dime Beauty Co.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Results available

Impact of a Corrie Cardiac Rehabilitation Program

NCT05238103
View directory record Official record
Conditions
Coronary Artery Disease, Myocardial Infarction, Myocardial Ischemia, Coronary Artery Occlusion, Coronary Artery Stenosis Stent, Bypass Graft Occlusion, Valve Heart Disease
Interventions
Corrie Hybrid Cardiac Rehabilitation Program
Combination Product
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
259 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 23, 2026, 4:44 AM EDT
Not yet recruiting No phase listed Observational

Wearable Technology in Heart Failure Patients

NCT07650669
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2040
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 4:44 AM EDT
Terminated Phase 2 Interventional Results available

Study of Ataluren (PTC124) in Nonambulatory Participants With Nonsense-Mutation-Mediated Duchenne/Becker Muscular Dystrophy (nmDMD/BMD)

NCT01009294
View directory record Official record
Conditions
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Interventions
Ataluren, Chronic Corticosteroid Therapy
Drug
Lead sponsor
PTC Therapeutics
Industry
Eligibility
7 Years and older · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Davis, California • Boston, Massachusetts • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Results available

Myocardial Infarction, COmbined-device, Recovery Enhancement Study

NCT03760796
View directory record Official record
Conditions
Acute Myocardial Infarction, Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction
Interventions
Corrie Health Digital Platform
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
4
States / cities
Baltimore, Maryland • Boston, Massachusetts • Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 29, 2021 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional

Restoring Energy With Sub-symptom Threshold Optimized Rehabilitation Exercise for Long COVID

NCT06172803
View directory record Official record
Conditions
Long Covid19, Exercise Intolerance, Riboflavin-Responsive
Interventions
Restoring Energy with Sub-symptom Threshold Aerobic Rehabilitation Exercise, Light Stretching/Breathing Exercises
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 70 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 6, 2024 · Synced Oct 23, 2026, 4:44 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Apple Health Study

NCT06958523
View directory record Official record
Conditions
Mental Health, Sleep, Exercise, Hormones, Metabolic Health, Hearing, Aging, Lifestyle Factors, Functional Capacity, Neurological Conditions, General Health, Wellbeing, Women's Health
Interventions
Not listed
Lead sponsor
Apple Inc.
Industry
Eligibility
18 Years and older
Enrollment
500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 23, 2026, 4:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Atopic Dermatitis With Accelerometry and Polysomnography (ADAP)

NCT05583019
View directory record Official record
Conditions
Atopic Dermatitis, Eczema, Healthy
Interventions
GENEActiv Accelerometry Device, Centrepoint Insights Watch (CPIW) Accelerometry Device, Apple Watch Accelerometry Device, Polysomnography, Videography
Device
Lead sponsor
SymmetryScience Group, Inc.
Industry
Eligibility
12 Years to 75 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Oct 23, 2026, 4:44 AM EDT
Enrolling by invitation No phase listed Observational

CHAMP For the Feeder: Tube Feeding Study

NCT06052891
View directory record Official record
Conditions
Feeding Disorders
Interventions
CHAMP Application
Device
Lead sponsor
Lori Erickson
Other
Eligibility
1 Month to 6 Years
Enrollment
245 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 23, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Wearables

NCT05159557
View directory record Official record
Conditions
Dementia, Mild Cognitive Impairment, Alzheimer Disease
Interventions
In-Home Technology System, Limited In-Home Technology
Device
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 23, 2026, 4:44 AM EDT