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ClinicalTrials.gov public records Last synced Oct 23, 2026, 8:49 AM EDT

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Showing 145–168 of 258 matching trials from the live ClinicalTrials.gov search.
Filters: Intervention: Apple Extract Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes

NCT04038515
View directory record Official record
Conditions
Nicotine, E-liquid Flavors
Interventions
Nicotine 0 mg/mL, Nicotine 6 mg/mL, Nicotine 12 mg/mL, Nicotine 24 mg/mL, 'Menthol' flavor, 'Menthol/Mint' flavor, 'Green Apple' flavor, 'Watermelon' flavor, 'Unflavored'
Drug · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 30 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Studying Glucose and Appetite Response With Alternatives to Soda Pop

NCT06427915
View directory record Official record
Conditions
Healthy Nutrition
Interventions
OLIPOP prebiotic soda, Traditional sugar-sweetened cola
Other
Lead sponsor
Olipop, PBC
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Oct 23, 2026, 8:49 AM EDT
Completed No phase listed Observational Results available

Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Language Training Program for Children With ASD

NCT02708290
View directory record Official record
Conditions
Autistic Disorder, Autism, ASD
Interventions
MITA Prefrontal Synthesis exercises - each activity adapts to deliver the exercise that is at the exact level of difficulty appropriate for a child at any given point in time
Other
Lead sponsor
ImagiRation, LLC
Industry
Eligibility
2 Years to 12 Years
Enrollment
6,454 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 27, 2020 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Technological Approach to Improved Breastfeeding Rates and Self-Efficacy

NCT05673317
View directory record Official record
Conditions
Breastfeeding
Interventions
"Breastfeeding at AU" Smartphone Application
Other
Lead sponsor
Augusta University
Other
Eligibility
Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Community Building Through Virtual, Team-Based Exercise on Burnout

NCT05194410
View directory record Official record
Conditions
Burnout, Professional, Burnout, Student, Community Building, Mentorship, Exercise
Interventions
First 3 months of virtual, team-based exercise, Second 3 months of virtual, team-based exercise
Behavioral
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years and older
Enrollment
422 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional

Patient and Caregiver Participation Through an Educational Health Information Technology System ("BMT Roadmap") in the Context of Hematopoietic Cell Transplantation

NCT03161665
View directory record Official record
Conditions
Patients Undergoing Bone Marrow Transplant (BMT)
Interventions
BMT Roadmap
Other
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2017 · Synced Oct 23, 2026, 8:49 AM EDT
Active, not recruiting Not applicable Interventional

A Study of Wearable Devices to Predict Migraines

NCT05755945
View directory record Official record
Conditions
Migraine
Interventions
eHealth Application
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Terminated No phase listed Observational

Electronic Patient Reported Outcomes in Measuring Health-Related Quality of Life in Patients With Stage I-IV Prostate Cancer Undergoing Treatment

NCT03197948
View directory record Official record
Conditions
Prostate
Interventions
Internet-Based Intervention
Other
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Other
Eligibility
18 Years and older · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 23, 2026, 8:49 AM EDT
Terminated Not applicable Interventional

Impact of a Biofeedback Intervention on Microbiome, Metabolome, and Clinical Outcomes in Pediatric IBD (Study 2)

NCT04296110
View directory record Official record
Conditions
IBD
Interventions
Biofeedback, Music Relaxation Therapy
Behavioral · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
8 Years to 17 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2024 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Asthma Mobile Health Application 2.0

NCT03248869
View directory record Official record
Conditions
Asthma
Interventions
Current Daily Survey, Mobile Health App
Other
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
7,752 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2017 · Synced Oct 23, 2026, 8:49 AM EDT
Not yet recruiting No phase listed Observational

Wearable Technology in Heart Failure Patients

NCT07650669
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2040
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Apple Watch Evaluation of Endodontics Occupational Stress

NCT07498348
View directory record Official record
Conditions
Occupational Stress
Interventions
Not listed
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the Use of Apple Watch Features for Identification of Cardiac Arrhythmias

NCT03769207
View directory record Official record
Conditions
Atrial Fibrillation, Arrhythmias, Cardiac, Atrial Flutter
Interventions
Ambulatory ECG
Device
Lead sponsor
Apple Inc.
Industry
Eligibility
22 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 20, 2020 · Synced Oct 23, 2026, 8:49 AM EDT
Recruiting Not applicable Interventional

The Apollo Device in Systemic Sclerosis for the Management of fatiguE, Raynaud Phenomenon and qualiTy of Life

NCT06675344
View directory record Official record
Conditions
Systemic Sclerosis (SSc)
Interventions
Apollo Neuro Device, Sham device
Device
Lead sponsor
Robyn T. Domsic, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
New Orleans, Louisiana • Ann Arbor, Michigan • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of an Eye Serum on Improving the Appearance of the Periorbital Area

NCT06143033
View directory record Official record
Conditions
Periorbital Area
Interventions
DIME Beauty Luminosity Eye Serum
Other
Lead sponsor
Dime Beauty Co.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 23, 2026, 8:49 AM EDT
Recruiting Phase 2 Interventional

Neurovascular Transduction During Exercise in Chronic Kidney Disease

NCT02947750
View directory record Official record
Conditions
Renal Insufficiency, Chronic
Interventions
6R-BH4, 6R-BH4 placebo, Folic acid, Exercise training, Stretching, Histidine and beta-alanine supplementation, Histidine and beta-alanine placebo
Drug · Other · Dietary Supplement
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
3
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human

NCT03911050
View directory record Official record
Conditions
Human Health, Polyphenols, Pharmacokinetics
Interventions
Apple consumption, Control group
Dietary Supplement
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

NightWare and Cardiovascular Health in Adults With PTSD

NCT05365607
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness, Nightmare, Endothelial Dysfunction
Interventions
NightWare, Sham NightWare
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
22 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Results available

Utility of At-home Monitoring of Exercise Capacity by App-based 6-minute Walk Test

NCT03893500
View directory record Official record
Conditions
Pulmonary Arterial Hypertension
Interventions
Home-based 6 minute walk test
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional

Patient-Centered Tablets: Applications for Inpatient Admissions

NCT02109601
View directory record Official record
Conditions
Mobile Health
Interventions
Extensive bedside training for accessing patient portal, Limited bedside training on patient portal use.
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional

An Interactive Mobile Health (mHealth) App as Intervention for High Anxiety and Depression in College Students

NCT07017569
View directory record Official record
Conditions
Anxiety, Depression - Major Depressive Disorder, Stress
Interventions
Mobile health application
Behavioral
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 23, 2026, 8:49 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Apple Health Study

NCT06958523
View directory record Official record
Conditions
Mental Health, Sleep, Exercise, Hormones, Metabolic Health, Hearing, Aging, Lifestyle Factors, Functional Capacity, Neurological Conditions, General Health, Wellbeing, Women's Health
Interventions
Not listed
Lead sponsor
Apple Inc.
Industry
Eligibility
18 Years and older
Enrollment
500,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Oct 23, 2026, 8:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Beverages Containing Orange or Apple Pomace on Digestive Health in Adults

NCT03749031
View directory record Official record
Conditions
Digestive Health
Interventions
Orange juice + Orange Pomace, Orange Juice, Apple Juice and Apple Pomace, Apple Juice
Other
Lead sponsor
PepsiCo Global R&D
Industry
Eligibility
18 Years to 60 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 20, 2019 · Synced Oct 23, 2026, 8:49 AM EDT
Recruiting Not applicable Interventional

The PROACTIVE Study for Black Elders

NCT06512727
View directory record Official record
Conditions
Musculoskeletal Pain, Chronic Pain, Osteoarthritis, Pain, Chronic, Movement Evoked Pain
Interventions
PROACTIVE Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 92 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 23, 2026, 8:49 AM EDT