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ClinicalTrials.gov public records Last synced Sep 13, 2026, 6:37 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Appliance Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

Training Early Social Language in Autism

NCT03427138
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Jasper, Parent Education
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Months to 59 Months
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Results available

Conservative Treatment of Patients With Temporomandibular Disorders

NCT01021306
View directory record Official record
Conditions
Temporomandibular Disorders
Interventions
Chiropractic w/Activator & Self Care, Dental Care & Self Care, Sham AMCT, Self-Care Only Group
Device · Other
Lead sponsor
Palmer College of Chiropractic
Other
Eligibility
21 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
3
States / cities
Coralville, Iowa • Davenport, Iowa • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2017 · Synced Sep 13, 2026, 6:37 PM EDT
Active, not recruiting Not applicable Interventional

PRISM Intervention Study

NCT03883139
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
JASPER, DTT (Discrete Trial Training)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
36 Months to 59 Months
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
3
States / cities
Los Angeles, California • Rochester, New York • Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a "Flash-free" Adhesive Resin for Orthodontic Bracket Bonding

NCT02030002
View directory record Official record
Conditions
Malocclusion
Interventions
APC Flash-Free Adhesive Coated Appliance System, APC II Adhesive Coated Appliance System
Device
Lead sponsor
University of Minnesota
Other
Eligibility
10 Years to 60 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional

Workflow Validation of an In-Home Feedback Controlled Mandibular Positioner

NCT03616327
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
MATRx in-lab, MATRx plus
Device
Lead sponsor
Zephyr Sleep Technologies
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

OA Therapy for Mouth-breathers Who Snore

NCT04876625
View directory record Official record
Conditions
Snoring, Mouth Breathing, Obstructive Sleep Apnea
Interventions
myTAP oral appliance plus mouth shield, myTAP oral appliance alone for first 4 weeks
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Results available

Dental Appliance for Parkinson's Disease

NCT04082663
View directory record Official record
Conditions
Parkinson Disease
Interventions
Dental Mouthpiece
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
30 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 23, 2021 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Results available

Efficacy of the OrthoApnea NOA® Mandibular Advancement Device in the Management of Obstructive Sleep Apnea.

NCT05139303
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Orthoapnea NOA®
Device
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years to 79 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study Will Test the Theory That Training With the Facial-Flex Exercise Device Will Improve Snoring in Patients

NCT01554904
View directory record Official record
Conditions
Primary Snoring, Sleep Apnea
Interventions
Facial-Flex
Device
Lead sponsor
Facial Concepts, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Use of Clear Aligners With Movement Enhancement Techniques

NCT02087163
View directory record Official record
Conditions
Malocclusion
Interventions
Movement Enhancement Technique, Clear Aligner
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
16 Years to 46 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional

Early Behavioral Intervention to Improve Social Communication Function in Infants With Tuberous Sclerosis Complex

NCT02687633
View directory record Official record
Conditions
Tuberous Sclerosis Complex
Interventions
JASPER
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Months to 36 Months
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Recruiting Not applicable Interventional

The Airports, Air Quality, and Asthma (AAA) Study

NCT07047430
View directory record Official record
Conditions
Pediatric Asthma
Interventions
Portable air cleaner with HEPA filter, Less effective portable air cleaner (no HEPA)
Device
Lead sponsor
University of Washington
Other
Eligibility
6 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intraoral Appliance (IOA) Model Evaluating the Efficacy of a Whitening Toothpaste

NCT07419685
View directory record Official record
Conditions
Dental Caries
Interventions
Negative Control Toothpaste, Active Comparator, Test Toothpaste
Drug
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Noblesville, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Results available

Combined Application of Electrical Stimulated Antagonist Contraction During Walking (Walking Study)

NCT02730598
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Hybrid Training System (HTS), Sensory TENS
Device
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
39 Years to 70 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2018 · Synced Sep 13, 2026, 6:37 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Prevalence of White Spot Lesions During Orthodontic Treatment With Fixed Appliances

NCT04186065
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Hiroko Nagaoka
Other
Eligibility
10 Years to 70 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 23, 2020 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize Enamel

NCT06242444
View directory record Official record
Conditions
Tooth Erosion
Interventions
Experimental Dentifrice, Placebo Control Dentifrice, Reference Dentifrice
Drug
Lead sponsor
HALEON
Industry
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Sep 13, 2026, 6:37 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Mandibular Advancement Device (MAD) in Pregnant Women With Obstructive Sleep Apnea (OSA)

NCT06256640
View directory record Official record
Conditions
Obstructive Sleep Apnea of Adult, Pregnancy Related
Interventions
Mandibular advancement Device
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Phase 2Phase 3 Interventional

Diabetes Technology Study of Real-Time Glucose Alerts in the Team Management of Diabetes

NCT00322478
View directory record Official record
Conditions
Diabetes Mellitus, Type 1
Interventions
Automated informatics driven education and social networking, Blood Glucose Notifications to Remote Caregivers, Frequency of Pattern Management
Behavioral
Lead sponsor
Diabetech
Industry
Eligibility
Not listed
Enrollment
432 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2015 · Synced Sep 13, 2026, 6:37 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Pilot Study for Feasibility of Using an Oral Appliance for Decreasing Snoring

NCT04900285
View directory record Official record
Conditions
Snoring
Interventions
Delta Dental Oral Device
Device
Lead sponsor
Norton Healthcare
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 13, 2026, 6:37 PM EDT
Completed Not applicable Interventional

Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea

NCT02489591
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Oral appliance, BluePro oral appliance
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 13, 2026, 6:37 PM EDT
Not yet recruiting Not applicable Interventional

Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2

NCT06783504
View directory record Official record
Conditions
Diabetes, Gastroparesis
Interventions
PERCUTANEOUS ELECTRICAL FIELD NERVE STIMULATION, Sham percutaneous electrical nerve field stimulation
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Not yet recruiting Not applicable Interventional

Fuzzle System for Appetite Control and Weight Management

NCT07527559
View directory record Official record
Conditions
Obesity & Overweight
Interventions
Fuzzle Intraoral Device, Lifestyle Management
Device · Behavioral
Lead sponsor
Fuzzle Operating Co.
Industry
Eligibility
18 Years to 65 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

IOA Preventing Occlusal Changes With MAD Use

NCT07103941
View directory record Official record
Conditions
Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite, Occlusal Changes, Tooth Migration, Posterior Open Bite
Interventions
AM Aligner, Exercise
Device · Behavioral
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 13, 2026, 6:37 PM EDT
Enrolling by invitation No phase listed Observational

Allied Cleft & Craniofacial Quality-Improvement and Research Network (ACCQUIREnet)

NCT02702869
View directory record Official record
Conditions
Cleft Lip, Cleft Palate, Cleft Lip and Palate
Interventions
cleft lip repair, cleft palate repair, oronasal fistula repair, pharyngoplasty, gingivoperiosteoplasty, LeFort-1 maxillary repositioning, rhinoplasty, myringotomy and tympanostomy tube placement, speech therapy, orthodontia, presurgical orthopedics, sound amplification for hearing
Procedure · Other · Device
Lead sponsor
Duke University
Other
Eligibility
1 Day to 22 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2031
U.S. locations
10
States / cities
Gainesville, Florida • Hollywood, Florida • Orlando, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 13, 2026, 6:37 PM EDT