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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Application of dehydrated human amniotic membrane Clear all
Recruiting Not applicable Interventional

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Venous Leg Ulcers

NCT07061613
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
NeoThelium FT (HCT/P 361)
Other
Lead sponsor
NuScience Medical Biologics, LLC
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Metairie, Louisiana • Slidell, Louisiana
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Postmarket Study to Evaluate Biovance® in Diabetic Foot Ulcers

NCT02506452
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Biovance®, Standard of Care, Diabetic Foot Ulcers
Other
Lead sponsor
Alliqua BioMedical, Inc
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
10
States / cities
Montgomery, Alabama • Phoenix, Arizona • Fresno, California + 7 more
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Open Wounds

NCT07041177
View directory record Official record
Conditions
Open Wound
Interventions
NeoThelium FT
Other
Lead sponsor
NuScience Medical Biologics, LLC
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Hammond, Louisiana
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

DHACM in Robotic Assisted Laparoscopic Prostatectomy (RALP)

NCT02526173
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
RALP using full nerve sparing technique, dHACM Application
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
40 Years to 70 Years · Male only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Celebration, Florida
Source: ClinicalTrials.gov public record
Updated Sep 27, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Withdrawn Not applicable Interventional

Dehydrated Human Amnion/Chorion Membrane (dHACM) for Recovery After Fractionated Ablative CO2 Laser Resurfacing of the Face

NCT01995604
View directory record Official record
Conditions
Scarring
Interventions
Application of Sterile 0.9% Saline Solution, Application of dHACM
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 12, 2014 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

A Single Center, Prospective, Case Series of the Treatment of Pressure Ulcers and Decubitus Ulcers.

NCT03529578
View directory record Official record
Conditions
Pressure Ulcer
Interventions
dHACM
Procedure
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Case Series of Weekly Applications of dHACM in Treatment of Pressure Ulcers

NCT02861560
View directory record Official record
Conditions
Pressure Ulcer
Interventions
dHACM
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
16 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers

NCT01693133
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Standard of Care: Moist Wound Therapy and Offloading, EpiFix plus Standard of Care
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
20
States / cities
Birmingham, Alabama • Bakersfield, California • Castro Valley, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Randomized Clinical Trial Using Amniotic Membrane in Robotic Assisted Laparoscopic Prostatectomy

NCT01832168
View directory record Official record
Conditions
Pudendal Nerve
Interventions
Robotic Assisted Laparoscopic Prostatectomy, Application of Absorbable Hemostat, Application of dehydrated human amniotic membrane
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
45 Years to 70 Years · Male only
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Use of dHACM in the Treatment of Venous Leg Ulcers

NCT02011503
View directory record Official record
Conditions
Leg Ulcer
Interventions
Multi-layer compression therapy, Application of dHACM
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
15
States / cities
Phoenix, Arizona • Carlsbad, California • Castro Valley, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Phase 4 Interventional

Pilot Study to Evaluate Clinical Outcomes With the Use of Biovance Following Keloid Scar Revision Surgery

NCT02521402
View directory record Official record
Conditions
Keloid Scar
Interventions
Biovance
Biological
Lead sponsor
Golla Center for Plastic Surgery
Other
Eligibility
21 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 12, 2015 · Synced Sep 24, 2026, 5:48 PM EDT
Enrolling by invitation Not applicable Interventional

A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers

NCT06453187
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
Urinary Bladder Matrix (UBM) sheet device for Venous Leg Ulcers, Urinary Bladder Matrix (UBM) sheet device for Diabetic Foot Ulcers, AmnioExcel Plus for Venous Leg Ulcers, AmnioExcel Plus for Diabetic Foot Ulcers, Standard of Care
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Vista, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Human Amniotic Membrane Grafting and Standard of Care Versus Standard of Care Alone in the Treatment of Venous Leg Ulcers

NCT01552447
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
EpiFix, Compression Therapy
Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
5
States / cities
Boca Raton, Florida • Framingham, Massachusetts • Tulsa, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2016 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

A Prospective, Double-Blinded, Randomized Controlled Trial of dHACM for Incisional Hernia Prophylaxis

NCT04417140
View directory record Official record
Conditions
Incisional Hernia
Interventions
dHACM (AmnioWrap)
Biological
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years and older
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Sep 24, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

NCT06681428
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers
Interventions
Allograft
Other
Lead sponsor
Tides Medical
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
9
States / cities
Fresno, California • Los Angeles, California • Vista, California + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2025 · Synced Sep 24, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Chronic Pressure Ulcers

NCT07158658
View directory record Official record
Conditions
Pressure Injury
Interventions
NeoThelium FT (HCT/P 361)
Other
Lead sponsor
NuScience Medical Biologics, LLC
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Bossier City, Louisiana • Rayville, Louisiana
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

dHACM in Lumbar Decompression and Microdiscectomy Surgery

NCT02300909
View directory record Official record
Conditions
Scarring, Spinal Stenosis, Herniated Disc
Interventions
Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 22, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Completed Not applicable Interventional

Amniotic Membrane in Total Knee Replacements to Reduce Scarring

NCT02088567
View directory record Official record
Conditions
Scarring
Interventions
Total Knee Arthroplasty, Application of dHACM
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 22, 2015 · Synced Sep 24, 2026, 5:48 PM EDT
Recruiting Not applicable Interventional

Dehydrated Human Amnion Membrane and Standard of Care Versus Standard of Care Alone in Nonhealing Diabetic Foot Ulcers

NCT06550596
View directory record Official record
Conditions
Diabetic Foot, Ulcer Foot, Foot Ulcer, Diabetic Foot Ulcer
Interventions
Standard of Care, Axolotl DualGraft + SOC
Other
Lead sponsor
Axolotl Biologix
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Thousand Oaks, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Limb Salvage Through Tissue Engineering: A Novel Treatment Modality Using Dehydrated Human Amnion/Chorion Membrane

NCT03521258
View directory record Official record
Conditions
Wounds, Trauma, Injury, Limb Salvage, Soft Tissue Injuries
Interventions
Dehydrated Human Amnion/Chorion Membrane, Flap-Based Reconstructive Surgery
Device · Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional

Amnioband and Standard of Care vs. Standard of Care Alone in the Treatment of Venous Leg Ulcers

NCT02609594
View directory record Official record
Conditions
Venous Leg Ulcers
Interventions
Weekly application of Amnioband, Biweekly application of Amnioband, Standard of Care
Other
Lead sponsor
SerenaGroup, Inc.
Network
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
8
States / cities
Boston, Massachusetts • Brick, New Jersey • Elmer, New Jersey + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Sep 24, 2026, 5:48 PM EDT
Terminated Phase 4 Interventional Results available

Amniotic Membrane Allograft Application in the Management of Venous Leg Ulcerations

NCT02929056
View directory record Official record
Conditions
Varicose Ulcer, Venous Insufficiency
Interventions
AmnioExCel dressing and compression therapy, SOC alginate dressing and compression therapy
Biological · Procedure
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Sep 24, 2026, 5:48 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers

NCT02838784
View directory record Official record
Conditions
Venous Ulcer, Foot Ulcer, Diabetic
Interventions
Artacent Human Amniotic Membrane, Standard of Care
Other · Procedure
Lead sponsor
Tides Medical
Industry
Eligibility
18 Years and older
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
7
States / cities
Arcadia, California • New Iberia, Louisiana • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2017 · Synced Sep 24, 2026, 5:48 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Role of Amnion Membrane Allografts in Nipple Preservation

NCT06073808
View directory record Official record
Conditions
Mastectomy, Gender Affirmation Surgery, Nipple Sparing Mastectomy, Prophylactic Mastectomy, Benign Breast Condition
Interventions
AmnioFix dehydrated Human Amnion/Chorion Membrane Allograft, Control Device
Device
Lead sponsor
Stanford University
Other
Eligibility
15 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 24, 2026, 5:48 PM EDT