- Conditions
- Gum Disease
- Interventions
- Arginine Toothpaste, Fluoride Toothpaste
- Device
- Lead sponsor
- Sukirth M Ganesan, BDS, PhD
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–13
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Dental Caries
- Interventions
- 0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice, 8.0% Arginine Dentifrice
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 10 Years to 14 Years
- Enrollment
- 2,025 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 8
- States / cities
- Loma Linda, California • Gainesville, Florida • Indianapolis, Indiana + 4 more
- Conditions
- Dental Caries
- Interventions
- Caries Free, Caries Active, Caries Free - Placebo, Caries Active - Placebo
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Plaque, Dental
- Interventions
- Colgate Cavity Protection, TOM's Superior Sensitivity Relief Toothpaste
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Piscataway, New Jersey
- Conditions
- Enamel Erosion
- Interventions
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 172 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Dental Caries
- Interventions
- Caries Free 1.5% Arginine, Caries Free Placebo Sodium Fluoride, Caries Active 1.5% Arginine, Caries Active- Placebo Sodium Fluoride
- Other
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 170 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Gingivitis
- Interventions
- 0.76% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Whittier, California
- Conditions
- Dentine Hypersensitivity
- Interventions
- Stannous fluoride dentifrice, Positive control dentifrice, Negative control dentifrice
- Drug
- Lead sponsor
- Procter and Gamble
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1,036 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Sensitivity, Tooth
- Interventions
- TOMs of Maine Sensitive SLS Free Xtra Fresh, Colgate Cavity protection toothpaste
- Device · Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Costa Mesa, California
- Conditions
- Caries,Dental
- Interventions
- L Arginine, Sodium Fluoride
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023
- U.S. locations
- 1
- States / cities
- Fair Lawn, New Jersey
- Conditions
- Xerostomia
- Interventions
- 8% Arginine toothpaste, 1000 ppm F toothpaste
- Device · Drug
- Lead sponsor
- Tufts University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Hypersensitivity
- Interventions
- Arginine/Calcium Carbonate, Mint Prophy paste - Fluoride free
- Device
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 79 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Hypersensitivity
- Interventions
- Toothpaste containing 8% Arginine, Colgate Cavity Protection Toothpaste
- Drug
- Lead sponsor
- Colgate Palmolive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Loma Linda, California