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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Arthroscopic Rotator Cuff Surgery Clear all
Completed Not applicable Interventional

Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears

NCT03295994
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Arthroscopic Rotator Cuff Surgery, Physical Therapy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
40 Years to 84 Years
Enrollment
187 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
19
States / cities
Phoenix, Arizona • San Francisco, California • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 23, 2026, 1:23 PM EDT
Completed Phase 4 Interventional Results available

Liposomal Bupivacaine Interscalene Blocks for Rotator Cuff Repair

NCT03587584
View directory record Official record
Conditions
Acute Pain
Interventions
liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Sep 23, 2026, 1:23 PM EDT
Terminated Phase 4 Interventional Results available

The Effect of EXPAREL® on Postsurgical Pain, and the Use of Narcotics

NCT03290196
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
EXPAREL 1.3 % in 20 ML Injection
Drug
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 72 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

NCT02588027
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy
Interventions
Ibuprofen, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 23, 2026, 1:23 PM EDT
Not yet recruiting Phase 1 Interventional

Impact of BPC-157 on Recovery Following Rotator Cuff Repair Surgery

NCT07803250
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
BPC-157, Sham (No Treatment)
Drug · Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 23, 2026, 1:23 PM EDT
Completed Phase 4 Interventional Results available

Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery

NCT01450007
View directory record Official record
Conditions
Shoulder Injury
Interventions
Ropivacaine, Dexamethasone, Normal saline
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 16, 2016 · Synced Sep 23, 2026, 1:23 PM EDT
Completed No phase listed Observational

Single Shot vs Continuous Interscalene Block for Rotator Cuff Repair

NCT01122745
View directory record Official record
Conditions
Pain, Rotator Cuff, Surgery
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 29, 2014 · Synced Sep 23, 2026, 1:23 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

BFR Therapy in Patients With Rotator Cuff Tears

NCT04384120
View directory record Official record
Conditions
Blood Flow Restriction
Interventions
Blood Flow Restriction Therapy, Traditional Therapy
Device · Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

BioBrace® Implant for Arthroscopic Repair of Full Thickness Rotator Cuff Tears

NCT05997381
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Arthroscopic rotator cuff repair with BioBrace® Implant augmentation., Arthroscopic rotator cuff repair
Device · Procedure
Lead sponsor
CONMED Corporation
Industry
Eligibility
40 Years to 70 Years
Enrollment
268 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 23, 2026, 1:23 PM EDT
Recruiting Not applicable Interventional

Cold and Compression After Rotator Cuff Repair (RCR)

NCT07516327
View directory record Official record
Conditions
High-grade Partial or Full Thickness Rotator Cuff Tears
Interventions
SOC (Standard of care), Cold and Compression
Other · Device
Lead sponsor
Ochsner Health System
Other
Eligibility
35 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Kenner, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 23, 2026, 1:23 PM EDT
Withdrawn Not applicable Interventional

Cryotherapy Following Rotator Cuff Repair Surgery

NCT04705376
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Breg Polarcare, Thermazone
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 23, 2026, 1:23 PM EDT
Not listed Not applicable Interventional

Study Comparing Patient Function and Satisfaction With Arthroscopic Subacromial Decompression Before and After Repair of Complete Rotator Cuff Tears

NCT01430598
View directory record Official record
Conditions
Rotator Cuff Tear, Acromial Spur
Interventions
Rotator Cuff Repair and Subacromial Decompression, Questionnaire
Procedure · Other
Lead sponsor
Ascension Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Grand Blanc, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 7, 2011 · Synced Sep 23, 2026, 1:23 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Can Testosterone Accelerate Injury Recovery After Arthroscopic Rotator Cuff Repair

NCT04345666
View directory record Official record
Conditions
Rotator Cuff Tears
Interventions
Testosterone cypionate, Placebos
Drug
Lead sponsor
Orthopedic Institute, Sioux Falls, SD
Other
Eligibility
45 Years to 75 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Sep 23, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Mesenchymal Stem Cell Augmentation in Patients Undergoing Arthroscopic Rotator Cuff Repair

NCT02484950
View directory record Official record
Conditions
Full Thickness Rotator Cuff Tear
Interventions
Mesenchymal stem cell augmentation in rotator cuff repair, Standard arthroscopic rotator cuff repair
Biological · Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Terminated Not applicable Interventional Results available

REGENETEN™ Bioinductive Implant System in Full-thickness Tears

NCT04450342
View directory record Official record
Conditions
Rotator Cuff Injuries
Interventions
Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery
Device · Procedure
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
40 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
8
States / cities
Rome, Georgia • Chicago, Illinois • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Recruiting Not applicable Interventional

Treatment of the Biceps With Concomitant Supraspinatus Tears

NCT05660031
View directory record Official record
Conditions
Supraspinatus Tear
Interventions
LHB Tenotomy, LHB Tenodesis
Procedure
Lead sponsor
La Tour Hospital
Other
Eligibility
50 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Ann Arbor, Michigan • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Withdrawn Phase 4 Interventional

The Effect of NSAIDs After a Rotator Cuff Repair Surgery.

NCT02153177
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
Rotator cuff repair, Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole, Hydrocodone/Acetaminophen
Procedure · Drug
Lead sponsor
University of Chicago
Other
Eligibility
45 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Sep 23, 2026, 1:23 PM EDT
Withdrawn Phase 3 Interventional Accepts healthy volunteers

Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block

NCT01538459
View directory record Official record
Conditions
Shoulder Pain, Injury of Shoulder Region, Disorder of Shoulder, Disorder of Rotator Cuff, Disorder of Tendon of Biceps
Interventions
Dexamethasone, Bupivacaine
Drug
Lead sponsor
Lifespan
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Newport, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 19, 2013 · Synced Sep 23, 2026, 1:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study

NCT03379324
View directory record Official record
Conditions
Rotator Cuff Tear, Fatty Atrophy
Interventions
Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
Biological
Lead sponsor
Applied Biologics, LLC
Industry
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 19, 2017 · Synced Sep 23, 2026, 1:23 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Exparel v Dexamethasone in RCR

NCT06575010
View directory record Official record
Conditions
Rotator Cuff Tears, Postoperative Pain
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Dexamethasone
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 23, 2026, 1:23 PM EDT
Completed Not applicable Interventional Results available

Bridge Device for Surgical Pain for Rotator Cuff Surgery

NCT06071884
View directory record Official record
Conditions
Pain, Rotator Cuff Injuries
Interventions
Bridge Percutaneous Nerve Field Stimulator
Device
Lead sponsor
Steven Orebaugh
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
West Mifflin, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 23, 2026, 1:23 PM EDT
Not listed Phase 4 Interventional

Evaluation of Post-Procedure Administration of Celecoxib Following Shoulder Surgery

NCT03305068
View directory record Official record
Conditions
Reverse or Primary Total Shoulder, Rotator Cuff- Full Thickness- Repair
Interventions
Celecoxib
Drug
Lead sponsor
St. Louis Joint Replacement Institute
Other
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Bridgeton, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 26, 2018 · Synced Sep 23, 2026, 1:23 PM EDT
Terminated Phase 4 Interventional Results available

LifeNet: Extracellular Matrix Graft in Rotator Cuff Repair

NCT03551509
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
ArthroFLEX ECM scaffold graft, Control, Alternative Treatment Group
Procedure · Biological
Lead sponsor
Gregory Gilot
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 23, 2026, 1:23 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery

NCT05009498
View directory record Official record
Conditions
Vitamin D Deficiency, Rotator Cuff Tears
Interventions
Vitamin D3 supplementation, Placebo
Dietary Supplement · Other
Lead sponsor
Community Memorial Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 16, 2021 · Synced Sep 23, 2026, 1:23 PM EDT