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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Intervention: Assist-Knee Clear all
Terminated Not applicable Interventional Results available

A 12-Week Home-Based Electrical Stimulation Program for Strength in Adults With Knee Osteoarthritis

NCT05765435
View directory record Official record
Conditions
Osteoarthritis, Osteoarthritis, Knee
Interventions
12-week exercise and walking program, NMES, FES
Other · Device
Lead sponsor
Cionic, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 25, 2026, 2:13 PM EDT
Not listed No phase listed Observational

Survivorship and Outcomes of Robotic-Arm Assisted Medial Unicompartmental Knee Arthroplasty

NCT03668717
View directory record Official record
Conditions
Osteoarthritis
Interventions
Robotic-arm assisted medical MCK implant
Device
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
St. Helena, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Sep 25, 2026, 2:13 PM EDT
Enrolling by invitation Not applicable Interventional

Patient Outcomes With Robotic-Assisted Total Knee Arthroplasty

NCT06203756
View directory record Official record
Conditions
Arthroplasties, Knee Replacement, Revision Arthroplasty
Interventions
Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex UC, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex PS, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex Revision
Device
Lead sponsor
Corin
Industry
Eligibility
Not listed
Enrollment
713 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2040
U.S. locations
6
States / cities
Flagstaff, Arizona • Middlebury, Connecticut • Rochester, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Sep 25, 2026, 2:13 PM EDT
Terminated No phase listed Observational Results available

Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty

NCT03023410
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
VERASENSE
Procedure
Lead sponsor
Orthosensor, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Phase 1 Interventional

Effect of Socket Wall Height With Vacuum Suspension for Above Knee Amputees

NCT01559909
View directory record Official record
Conditions
Amputation
Interventions
Vacuum assisted socket technology (Harmony System, Otto Bock Healthcare)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
21 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Stony Brook, New York • West Babylon, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2014 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobilizing Hispanics With Knee Osteoarthritis

NCT06522906
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Muscle Strengthening, General Physical Activity, Education
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 90 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Orthosensor vs Conventional Total Knee Arthroplasty

NCT03628378
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Verasense
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Bronxville, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty

NCT03653416
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Ipack, Bupivacaine, Peri Articular Infiltration
Device · Drug · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 75 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Phase 4 Interventional

Computer Assisted Total Knee Replacement

NCT00279838
View directory record Official record
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Computer Assisted Navigation Knee Replacement
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2011 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Autologous Alpha-2 Macroglobulin Rich Plasma, Safety and Efficacy in Symptomatic Moderate Knee Osteoarthritis

NCT06329492
View directory record Official record
Conditions
Osteoarthritis, OA, Knee Osteoarthritis
Interventions
Autologous Alpha-2 Macroglobulin Rich Plasma (A2MRP)
Biological
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

MOTION Clinical Trial

NCT06843980
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
MISHA Knee System, Non-Surgical Treatment
Device · Other
Lead sponsor
Moximed
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
9
States / cities
Davis, California • Oceanside, California • Sacramento, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Completed No phase listed Observational

Total Knee Arthroplasty Guidance Systems Study

NCT02830997
View directory record Official record
Conditions
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Interventions
Stereotactic guidance system
Device
Lead sponsor
Ormonde M. Mahoney, MD
Other
Eligibility
45 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Sep 25, 2026, 2:13 PM EDT
Completed No phase listed Observational

AlterG ACL Return to Running Case Series

NCT02335645
View directory record Official record
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Body Weight Supported Treadmill Use of Patients with ACL Reconstruction
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Westerville, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 25, 2026, 2:13 PM EDT
Not listed No phase listed Observational

Survivorship and Outcomes of Robotically Assisted Patellofemoral UKA

NCT01947686
View directory record Official record
Conditions
Patellofemoral Knee Arthroplasty
Interventions
Robotically guided patellofemoral UKA isolated patellofemoral implants
Device
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
2
States / cities
St. Helena, California • Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Sep 4, 2018 · Synced Sep 25, 2026, 2:13 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

CT Assessment of Minimally Invasive Surgery and Computer Assisted Navigation in Total Knee Arthroplasty

NCT00409266
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Computer assisted navigation
Device
Lead sponsor
Stryker Instruments
Industry
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Plymouth, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Sep 25, 2026, 2:13 PM EDT
Not yet recruiting Not applicable Interventional

Knee Replacement Rehabilitation Care Pathways

NCT07598539
View directory record Official record
Conditions
Knee Replacement, Total
Interventions
TKA Journey - patient education, Optimized Rehab Scheduling, Usual Rehab
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Not applicable Interventional

Dynamic Quadriceps Muscle Stimulation for Treatment of Patellofemoral Pain

NCT02243332
View directory record Official record
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
KneeStim mobile rehabilitation assistance device
Device
Lead sponsor
Articulate Labs
Industry
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 25, 2026, 2:13 PM EDT
Completed No phase listed Observational

An Open Label Data Collection Study of My Connect Post-Op, a Post-Operative Communication Tool

NCT07120191
View directory record Official record
Conditions
Total Hip Replacement, Total Knee Replacement
Interventions
post op communication software
Device
Lead sponsor
Concentra AI, inc
Industry
Eligibility
22 Years to 80 Years
Enrollment
652 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Phoenix, Arizona • Wichita, Kansas • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Active, not recruiting Not applicable Interventional

Improving Prosthetic Provision in Rural Communities: Limb Scanning With Caregiver Assistance

NCT05884203
View directory record Official record
Conditions
Lower Extremity Amputation
Interventions
Caregiver socket, Prosthetist socket
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Mobilization With Movement on Weight Bearing Ankle Dorsiflexion Range of Motion

NCT05844072
View directory record Official record
Conditions
Ankle Joint Contracture
Interventions
Mobilization with movement
Procedure
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Not applicable Interventional

The Impact of a Technology-enabled Decision Aid, for Patients With Hip and Knee Osteoarthritis on Decision Quality, Level of Shared Decision-making, Patient Satisfaction and Magnitude of Limitations

NCT03956004
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
OM1 Dell Shared Decision Making Tool, Education material from OM1 Dell Shared Decision Making Tool
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
45 Years to 89 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Sep 25, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

Multisite Transspinal Stimulation for Augmenting Recovery in Spinal Cord Injury

NCT07204184
View directory record Official record
Conditions
Spinal Cord Injuries (Complete and Incomplete)
Interventions
Multisite transspinal stimulation at rest, Multisite transspinal stimulation during robotic gait training
Device
Lead sponsor
Maria Knikou, PT, MBA, PhD
Other
Eligibility
18 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 25, 2026, 2:13 PM EDT
Completed Not applicable Interventional Results available

Wearable Lower Extremity Exoskeleton to Promote Walking in Persons With Multiple Sclerosis

NCT02519244
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Ekso® (Wearable lower limb exoskeleton)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 28, 2019 · Synced Sep 25, 2026, 2:13 PM EDT
Recruiting Not applicable Interventional

Nomad P-KAFO Study

NCT05644522
View directory record Official record
Conditions
Cerebrovascular Accident, Post-polio Syndrome, Spinal Cord Injuries, Multiple Sclerosis, Muscular Dystrophy, Paralysis
Interventions
Indego Nomad® Powered Knee-Ankle-Foot Orthosis (P-KAFO) (Parker Hannifin Corp., Cleveland, OH)
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 25, 2026, 2:13 PM EDT