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ClinicalTrials.gov public records Last synced Sep 12, 2026, 5:49 PM EDT

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Showing 1–24 of 376 matching trials from the live ClinicalTrials.gov search.
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Filters: Intervention: Atrial Ablation Clear all
Completed Phase 1 Interventional

RF Ablation of Atrial Fibrillation

NCT00265629
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
RF catheter ablation
Device
Lead sponsor
C. R. Bard
Industry
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2013 · Synced Sep 12, 2026, 5:49 PM EDT
Terminated Phase 2 Interventional Results available

Metformin as an Upstream Therapy in Atrial Fibrillation

NCT02931253
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Metformin
Drug
Lead sponsor
The Guthrie Clinic
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Sayre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Sep 12, 2026, 5:49 PM EDT
Recruiting Not applicable Interventional

A Study of VARIPULSE Catheter in Participants With Persistent Atrial Fibrillation Undergoing Pulmonary Vein and Superior Vena Cava Isolation

NCT07527299
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
VARIPULSE Catheter System, LAAO Device
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
1,070 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
3
States / cities
Tucson, Arizona • Jonesboro, Arkansas • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 12, 2026, 5:49 PM EDT
Not listed No phase listed Observational

Dielectric Tissue Imaging in Cavotricuspid Isthmus Ablation

NCT04438395
View directory record Official record
Conditions
Atrial Fibrillation and Flutter
Interventions
Cardiac ablation via catheter
Device
Lead sponsor
EPD Solutions, A Philips Company
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Sep 12, 2026, 5:49 PM EDT
Recruiting No phase listed Observational

The Long-term Safety and Effectiveness Evaluation of the QDOT MICRO System Use in Conjunction With VISITAG SURPOINT Module for the Treatment of Symptomatic Drug Refractory Paroxysmal Atrial Fibrillation.

NCT06324201
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
Ablation Procedure
Device
Lead sponsor
Heart Rhythm Clinical and Research Solutions, LLC
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
21
States / cities
Birmingham, Alabama • Mobile, Alabama • Ventura, California + 17 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Sep 12, 2026, 5:49 PM EDT
Completed No phase listed Observational

Vektor vMap™ Clinical Validation Study

NCT04559061
View directory record Official record
Conditions
Cardiac Arrhythmia, Atrial Fibrillation, Ventricular Arrythmia, Premature Ventricular Complexes Multiple, Ventricular Tachycardia, Ventricular Fibrillation, Premature Atrial Complex, Atrioventricular Reentrant Tachycardia
Interventions
Cardiac ablation procedure
Device
Lead sponsor
Vektor Medical
Industry
Eligibility
22 Years to 100 Years
Enrollment
225 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Charleston, California • La Jolla, California • San Diego, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional

Better Outcomes for Anticoagulation Treatment Through Observation of Atrial Rhythm

NCT03515083
View directory record Official record
Conditions
Non-valvular Atrial Fibrillation
Interventions
Alive Cor Kardia mobile electrocardiogram monitor
Device
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 11, 2023 · Synced Sep 12, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

NCT05462145
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
Interventions
Globe Pulsed Field System
Device
Lead sponsor
Kardium Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
549 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
12
States / cities
Birmingham, Alabama • Jonesboro, Arkansas • San Francisco, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Phase 3 Interventional Results available

HeartLight Ablation in Patients With Paroxysmal Atrial Fibrillation (PAF)

NCT01456000
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
EAS-AC (HeartLight), Control Arm Ablation
Device · Procedure
Lead sponsor
CardioFocus
Industry
Eligibility
18 Years to 75 Years
Enrollment
405 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
21
States / cities
Birminham, Alabama • Palo Alto, California • Sacramento, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Sep 12, 2026, 5:49 PM EDT
Completed No phase listed Observational

RHYTHMIA vs CARTO in Redo Ablation Procedures for Atrial Fibrillation

NCT04835844
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
CARTO, RHYTHMIA
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Esophageal Deviation in Atrial Fibrillation Ablation

NCT03261973
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
DV8
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Phase 3 Interventional Results available

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)

NCT00392054
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Comparison of Percutaneous Closure to Manual Compression for Hemostasis

NCT04180540
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Percutaneous Closure, Manual Compression
Device · Other
Lead sponsor
Michael S. Lloyd
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Sep 12, 2026, 5:49 PM EDT
Terminated No phase listed Observational

Radiofrequency Ablation of Ectopic Atrial Tachycardia

NCT00267982
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 21 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2008
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2011 · Synced Sep 12, 2026, 5:49 PM EDT
Active, not recruiting No phase listed Observational

ADVENT Post Approval Study

NCT06431815
View directory record Official record
Conditions
Paroxysmal Atrial Fibrillation
Interventions
FARAPULSE™ Pulsed Field Ablation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
25
States / cities
Mobile, Alabama • Scottsdale, Arizona • Oakland, California + 20 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 12, 2026, 5:49 PM EDT
Completed No phase listed Observational

The Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

NCT01148914
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Inflammatory biomarkers
Other
Lead sponsor
Texas Cardiac Arrhythmia Research Foundation
Other
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2012 · Synced Sep 12, 2026, 5:49 PM EDT
Terminated Not applicable Interventional Results available

Deviating the Esophagus in Atrial Fibrillation Ablation

NCT01546168
View directory record Official record
Conditions
Esophageal Deviation, Atrial Fibrillation, Ablation
Interventions
esophageal deviation with IDE device
Device
Lead sponsor
Vivek Reddy
Other
Eligibility
18 Years to 80 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Orlando, Florida • Boston, Massachusetts • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 12, 2026, 5:49 PM EDT
Completed No phase listed Observational

Screening for Sleep Apnea in Patients Undergoing Atrial Fibrillation Ablation

NCT02332096
View directory record Official record
Conditions
Atrial Fibrillation, Obstructive Sleep Apnea, Cardiac Arrhythmias
Interventions
Home Sleep Testing Device
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2020 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional

One More Magnetic Resonance Imaging

NCT02293070
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Delayed Enhanced Cardiac Magnetic Resonance Imaging, Cryoablation
Other · Procedure
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

Comparison of Propofol and Sevoflurane as a Primary Anesthetic for Cardiac Ablation of Atrial Fibrillation.

NCT02697448
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
propofol, sevoflurane
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Sep 12, 2026, 5:49 PM EDT
Withdrawn Not applicable Interventional

CONVERGE CAP Study-For The Treatment Of Symptomatic Persistent or Long-standing Persistent AF

NCT04239534
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Convergence Of Epicardial And Endocardial RF Ablation
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
8
States / cities
Birmingham, Alabama • Huntsville, Alabama • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Sep 12, 2026, 5:49 PM EDT
Active, not recruiting Not applicable Interventional

A Study of Assessment on Safety and Effectiveness of BWI Pulsed Field Ablation With OMNYPULSE Catheter for the Treatment of Paroxysmal Atrial Fibrillation (PAF)

NCT06455098
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
OMNYPULSE™ Catheter with the TRUPULSE Generator
Device
Lead sponsor
Biosense Webster, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
39
States / cities
Phoenix, Arizona • Burlingame, California • Larkspur, California + 30 more
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 12, 2026, 5:49 PM EDT
Completed No phase listed Observational

Novel Cardiac Signal Processing System

NCT04112433
View directory record Official record
Conditions
Cardiac Arrhythmia
Interventions
PURE EP 2
Device
Lead sponsor
BioSig Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Jacksonville, Florida • Boston, Massachusetts • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 10, 2022 · Synced Sep 12, 2026, 5:49 PM EDT
Completed Not applicable Interventional Results available

DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation

NCT03643224
View directory record Official record
Conditions
Persistent Atrial Fibrillation, Atrial Fibrillation
Interventions
Radiofrequency Ablation
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years and older
Enrollment
376 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Orlando, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 12, 2026, 5:49 PM EDT